CAS 39562-70-4
:Nitrendipina
Descripción:
Nitrendipina es un bloqueador de canales de calcio utilizado principalmente en el tratamiento de la hipertensión y la angina de pecho. Pertenece a la clase de compuestos dihidropiridínicos, que se caracterizan por su capacidad para inhibir selectivamente la entrada de calcio a través de los canales de calcio tipo L en el músculo liso vascular y el tejido cardíaco. Esta acción conduce a la vasodilatación y a una disminución subsiguiente de la presión arterial. Nitrendipina es conocido por su alta lipofilia, lo que mejora su absorción y distribución en el cuerpo. El compuesto generalmente presenta una larga vida media, lo que permite una dosificación una vez al día en entornos clínicos. Su estructura química incluye un grupo nitro, que contribuye a sus propiedades farmacológicas. Nitrendipina es generalmente bien tolerado, pero al igual que otros bloqueadores de canales de calcio, puede causar efectos secundarios como dolor de cabeza, rubor o edema periférico. Al igual que con cualquier medicamento, es importante considerar las contraindicaciones y las posibles interacciones con otros fármacos. En general, Nitrendipina es un agente eficaz en el manejo de condiciones cardiovasculares, contribuyendo a mejorar los resultados en los pacientes.
Fórmula:C18H20N2O6
InChI:InChI=1/C18H20N2O6/c1-5-26-18(22)15-11(3)19-10(2)14(17(21)25-4)16(15)12-7-6-8-13(9-12)20(23)24/h6-9,15-16H,5H2,1-4H3/t15?,16-/m1/s1
Clave InChI:InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=CC(N(=O)=O)=CC=C2
Sinónimos:- (.+-.)-Bay E 5009
- (.+-.)-Nitrendipine
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
- Baylotensin
- Bayotensin
- Baypress
- Bylotensin
- Cardif
- Deiten
- Nidrel
- Nitrendipin
- Nitrendipino
- Nitrepin
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester
- 3-ethyl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
- 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
- 3-ethyl 5-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydropyridine-3,5-dicarboxylate
- ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate
- NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE
- ylmethylester
- NITRENDIPINE EPN(CRM STANDARD)
- (NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI)
- NITRENDIPINE >95% CA2+ CHANNEL BLOCKER,
- ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy
- 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy
- NITRENDIPINE MM(CRM STANDARD)
- baye5009
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Nitrendipine
CAS:Fórmula:C18H20N2O6Pureza:>98.0%(HPLC)(N)Forma y color:White to Yellow powder to crystalPeso molecular:360.37Nitrendipine
CAS:L-type calcium channel blockerFórmula:C18H20N2O6Forma y color:PowderPeso molecular:360.37NITRENDIPINE FOR PEAK IDENTIFICATION CRS
CAS:NITRENDIPINE FOR PEAK IDENTIFICATION CRSFórmula:C18H20N2O6Peso molecular:360.3612Nitrendipine
CAS:Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.Fórmula:C18H20N2O6Pureza:99% - 99.55%Forma y color:SolidPeso molecular:360.3612Ref: TM-T0119
10mg35,00€25mg52,00€1mL*10mM (DMSO)52,00€50mg67,00€100mg113,00€200mg172,00€500mg268,00€1g414,00€3-Ethyl 5-Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CAS:Fórmula:C18H20N2O6Pureza:95%Forma y color:SolidPeso molecular:360.3612Nitrendipine
CAS:Fórmula:C18H20N2O6Pureza:≥ 97.0%Forma y color:Pale yellow to yellow or green powderPeso molecular:360.36Nitrendipine 100 µg/mL in Acetonitrile
CAS:Fórmula:C18H20N2O6Forma y color:Single SolutionPeso molecular:360.36Nitrendipine (Standard)
CAS:Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Fórmula:C18H20N2O6Peso molecular:360.3612Nitrendipine
CAS:Producto controladoApplications Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
References Ventura, H.O., et al.: Am. J. Cardiol., 51, 783 (1983); Kann, J. et al.: Brit. J. Clin. Pharmacol., 33, 51 (1992);Fórmula:C18H20N2O6Forma y color:NeatPeso molecular:360.36Nitrendipine
CAS:3-Ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateFórmula:C18H20N2O6Pureza:98%Peso molecular:360.36(RS)-Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
CAS:Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate is a propranolol hydrochloride derivative that has vasodilatory effects. It is used as a nitrovasodilator to treat angina pectoris and high blood pressure. Methyl ethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate binds to the alpha1 adrenergic receptors in the heart and causes vasodilation by inhibiting the release of norepinephrine from sympathetic nerves. This drug also inhibits the binding of norepinephrine to cardiac beta receptors which decreases the heart rate and contractility of cardiac muscle. Methyl ethyl 1,4-dihydro-2,6Fórmula:C18H20N2O6Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:360.36 g/molNitrendipine in Acetonitrile
CAS:AcetonitrileFórmula:C18H20N2O6Forma y color:SolidPeso molecular:360.4
