CAS 444911-05-1

Fórmula: C20H29NO5S

InChI: InChI=1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17-,20-/m1/s1

Clave InChI: NSHPHXHGRHSMIK-WAXGXQFOSA-N

SMILES: C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O2)([C@H]3CSC(=O)N3)O)OC(=O)/C=C(\CC/C=C1)/C

16-epi-Latrunculin B

CAS: 444911-05-1

Fórmula: C₂₀H₂₉NO₅S

Peso molecular: 395.5

Ref: 7W-GL0386

16-epi Latrunculin B

CAS: 444911-05-1

16-epiLatrunculin B, a stereoisomer of the actin polymerization inhibitor latrunculin B, was initially isolated from the Red Sea sponge N. magnifica. At concentrations of 5-10 µg/ml, it disrupts microfilament activity in actin disruption assays and exhibits cytotoxic effects on mouse KA31T and NIH3T3 tumor cells, with GI50 values of 1 and 4 µg/ml, respectively. Furthermore, it shows antiviral activity against herpes simplex type 1 virus, with an ED50 of 1 µg/ml.

Fórmula: C₂₀H₂₉NO₅S

Forma y color: Solid

Peso molecular: 395.5

Ref: TM-TN7265