CAS 479-18-5
:diprofilina
Descripción:
diprofilina es un derivado de xantina que exhibe propiedades broncodilatadoras, lo que lo hace útil en el tratamiento de condiciones respiratorias como el asma y la enfermedad pulmonar obstructiva crónica (EPOC). Se caracteriza por su capacidad para relajar el músculo liso bronquial, mejorando así el flujo de aire y aliviando los síntomas del broncoespasmo. Químicamente, diprofilina es conocido por su toxicidad relativamente baja y buena tolerabilidad en los pacientes. Tiene una solubilidad moderada en agua y a menudo se administra en forma oral. La sustancia actúa inhibiendo la fosfodiesterasa, lo que lleva a niveles aumentados de AMP cíclico, que contribuyen a sus efectos broncodilatadores. Además, diprofilina puede tener propiedades diuréticas leves y puede influir en la función cardíaca. Su farmacocinética implica absorción, distribución, metabolismo y excreción, que son importantes para determinar los regímenes de dosificación. En general, diprofilina es un agente terapéutico valioso en la medicina respiratoria, con un perfil que apoya su uso en el manejo de la obstrucción de las vías respiratorias.
Fórmula:C10H14N4O4
InChI:InChI=1/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3/t6-/m1/s1
Clave InChI:InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N
SMILES:C(C(CO)O)N1C2=C(N(C)C(=O)N(C)C2=O)N=C1
Sinónimos:- (Rac)-diprophylline
- 1H-Purine-2,6-dione, 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-
- 7-(2,3-Dihydroxypropyl)-1,3-dimethylxanthine
- 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 7-(2,3-Dihydroxypropyl)theophylline
- 7-(β,γ-Dihydroxypropyl)theophylline
- 7-[(2R)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- 7-[(2S)-2,3-dihydroxypropyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- AFI-phyllin
- Airet
- Aristophyllin
- Asthmolysin
- Astmamasit
- Astmophysine
- Astrophyllin
- Athmolysin
- Chlordehydromethyl Testosterone Acetate
- Circain
- Circair
- Cor-Theophyllin
- Cor-Theophylline
- Coronal
- Coronarin
- Corphyllin
- Dilor
- Diphyllin
- Diphylline
- Diphylline (pharmaceutical)
- Diprofilina
- Diprofillin
- Diprophyllin
- Dyphylline
- Emfaseem
- Glyfyllin
- Glyphyllin
- Glyphylline
- Hidroxiteofillina
- Hiphyllin
- Hyphylline
- Isophyllen
- Lufyllin
- Lufyllin-EPG
- Neo-Vasophylline
- Neophyl
- Neophyllin
- Neophyllin M
- Neophylline
- Neostenovasan
- Neothyllin
- Neothylline
- Neotilina
- Neufil
- Neutrafil
- Neutrafillina
- Neutraphyllin
- Neutraphylline
- Neutroxantina
- Nsc 14305
- Nsc 40844
- Prophyllen
- Propyphyllin
- Protheophylline
- Purifilin
- Silbephyllin
- Silbephylline
- Solufilin
- Solufyllin
- Soluphyllin
- Synthophylline
- Tefilan
- Teofen
- Theal
- Theal ampules
- Thefulan
- Thefylan
- Theophylline, 7-(2,3-dihydroxypropyl)-
- 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
- 7-(BETA,GAMMA-DIHYDROXYPROPYL)-THEOPHYLLINE
- TIMTEC-BB SBB003125
- 1,3-Dimethyl-7-(2,3-dihydroxypropyl)xanthine
- (1,2-Dihydroxy-3-propyl)thiophyllin
- 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
- DIPROPYHYLLIN
- 7-(2,3-dihydroxypropyl)-1,3-dimethyl-purine-2,6-dione
- DIPROPHYLLINE
- 7(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1h-purine-6-dione
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7-(2,3-Dihydroxypropyl)theophylline
CAS:Fórmula:C10H14N4O4Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:254.25Dyphylline
CAS:An adenosine receptor antagonist, phosphodiesterase inhibitor and vasodilatorFórmula:C10H14N4O4Forma y color:White, Powder or crystalline powderPeso molecular:254.25DIPROPHYLLINE CRS
CAS:DIPROPHYLLINE CRSFórmula:C10H14N4O4Forma y color:Crystalline Powder. White. Whitish. Powder.Peso molecular:254.2426Dyphylline
CAS:Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or includedFórmula:C10H14N4O4Forma y color:White PowderPeso molecular:254.1015Diphylline
CAS:Diphylline is a bronchodilator with mild vasodilator and diuretic properties, used for asthma, bronchitis, and emphysema.Fórmula:C10H14N4O4Pureza:98.54%Forma y color:SolidPeso molecular:254.24267-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS:Fórmula:C10H14N4O4Pureza:98%Forma y color:SolidPeso molecular:254.2426Dyphylline
CAS:Producto controladoApplications Bronchodilator.
References Reitz, C., et al.: Eur. J. Pharm. Sci., 35, 335 (2008), Fliri, A., et al.: J. Med. Chem., 52, 8038 (2009), Dresen, S., et al.: Anal. Bioanal. Chem., 396, 2425 (2010),Fórmula:C10H14N4O4Forma y color:NeatPeso molecular:254.247-(2,3-Dihydroxypropyl)theophylline
CAS:7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dioneFórmula:C10H14N4O4Pureza:98%Peso molecular:254.24Dyphylline
CAS:Producto controladoDyphylline is a pharmaceutical drug that is used to treat asthma and chronic pulmonary obstructive disease. It is also used as a bronchodilator to relieve the symptoms of asthma and other respiratory disorders by relaxing the air passages. Dyphylline works by increasing the availability of oxygen to the lungs, which helps to relax the muscles around the airways. This leads to an increase in airflow into and out of the lungs. The drug inhibits bacterial growth by inhibiting chemotactic activity and hydroxyl group-dependent reactions, including protein synthesis. It also has potent antimicrobial activity against a wide range of microorganisms, including some strains of bacteria that are resistant to erythromycin and metoprolol succinate, which are two common antibiotics for treating respiratory infections. Dyphylline has been shown to have no effect on human serum albumin levels or on renal function (e.g., glomerular filtration rate).
Fórmula:C10H14N4O4Pureza:Min. 95%Forma y color:PowderPeso molecular:254.24 g/mol7-(2,3-Dihydroxypropyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
CAS:Fórmula:C10H14N4O4Pureza:95.0%Forma y color:SolidPeso molecular:254.246
