CAS 47931-85-1

Calcitonina (salmón)

Descripción:

Calcitonina (salmón) es una hormona peptídica que juega un papel crucial en la homeostasis del calcio y el metabolismo óseo. Se deriva de la especie de salmón, que tiene una forma más potente en comparación con la calcitonina humana. Esta sustancia está compuesta por 32 aminoácidos y es conocida por su capacidad para reducir los niveles de calcio en sangre al inhibir la actividad de los osteoclastos, lo que reduce la resorción ósea. La calcitonina también promueve la excreción renal de calcio y fosfato, contribuyendo aún más a sus efectos hipocalcémicos. Se utiliza comúnmente en entornos clínicos para el tratamiento de condiciones como la osteoporosis y la enfermedad de Paget. El número CAS 47931-85-1 identifica de manera única esta formulación específica de calcitonina. En términos de propiedades físicas, Calcitonina (salmón) se administra típicamente por inyección debido a su naturaleza peptídica, que limita su biodisponibilidad cuando se toma por vía oral. Sus efectos terapéuticos son generalmente rápidos, lo que lo convierte en una opción valiosa en el manejo de la hipercalcemia y trastornos relacionados.

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

InChI: InChI=1/C145H240N44O48S2/c1-65(2)45-86(175-139(232)110(70(11)12)183-136(229)99-63-239-238-62-79(148)117(210)178-96(59-191)134(227)174-92(52-104(151)202)131(224)172-90(49-69(9)10)129(222)180-98(61-193)135(228)187-114(74(16)197)142(235)181-99)118(211)158-55-106(204)162-80(25-18-20-40-146)120(213)169-89(48-68(7)8)128(221)179-97(60-192)133(226)167-83(34-37-102(149)200)122(215)165-85(36-39-109(207)208)123(216)171-88(47-67(5)6)127(220)173-91(51-77-54-156-64-161-77)130(223)164-81(26-19-21-41-147)121(214)170-87(46-66(3)4)126(219)166-84(35-38-103(150)201)125(218)186-113(73(15)196)141(234)177-94(50-76-30-32-78(199)33-31-76)143(236)189-44-24-29-101(189)137(230)168-82(27-22-42-157-145(154)155)124(217)185-112(72(14)195)140(233)176-93(53-105(152)203)132(225)184-111(71(13)194)138(231)160-56-107(205)163-95(58-190)119(212)159-57-108(206)182-115(75(17)198)144(237)188-43-23-28-100(188)116(153)209/h30-33,54,64-75,79-101,110-115,190-199H,18-29,34-53,55-63,146-148H2,1-17H3,(H2,149,200)(H2,150,201)(H2,151,202)(H2,152,203)(H2,153,209)(H,156,161)(H,158,211)(H,159,212)(H,160,231)(H,162,204)(H,163,205)(H,164,223)(H,165,215)(H,166,219)(H,167,226)(H,168,230)(H,169,213)(H,170,214)(H,171,216)(H,172,224)(H,173,220)(H,174,227)(H,175,232)(H,176,233)(H,177,234)(H,178,210)(H,179,221)(H,180,222)(H,181,235)(H,182,206)(H,183,229)(H,184,225)(H,185,217)(H,186,218)(H,187,228)(H,207,208)(H4,154,155,157)

SMILES: CC(C)CC(C(=NCC(=NC(CCCCN)C(=NC(CC(C)C)C(=NC(CO)C(=NC(CCC(=N)O)C(=NC(CCC(=O)O)C(=NC(CC(C)C)C(=NC(Cc1cnc[nH]1)C(=NC(CCCCN)C(=NC(CC(C)C)C(=NC(CCC(=N)O)C(=NC(C(C)O)C(=NC(Cc1ccc(cc1)O)C(=O)N1CCCC1C(=NC(CCCNC(=N)N)C(=NC(C(C)O)C(=NC(CC(=N)O)C(=NC(C(C)O)C(=NCC(=NC(CO)C(=NCC(=NC(C(C)O)C(=O)N1CCCC1C(=N)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(C(C)C)N=C(C1CSSCC(C(=NC(CO)C(=NC(CC(=N)O)C(=NC(CC(C)C)C(=NC(CO)C(=NC(C(C)O)C(=N1)O)O)O)O)O)O)N)O)O

Sinónimos:

• Calcitonin (salmon I)
• Thyrocalcitonin Salmon
• H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2 (Disulfide bond)
• Thyrocalcitonin
• Salmon calcitonin
• Salcitonin
• Salmon Calcitonin acetate
• Salmon
• Calcitonin salmon Acetate
• Calciben
• Calcimar
• Calcitonin (Lachs)
• Calcitonin (salmon reduced) cyclic (1→7)-disulfide
• Calcitonina (Salmon)
• Calcitonine (Saumon)
• Calsyn
• Calsynar
• Catonin
• Karil
• L-Prolinamide, L-cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucylglycyl-L-lysyl-L-leucyl-L-seryl-L-glutaminyl-L-α-glutamyl-L-leucyl-L-histidyl-L-lysyl-L-leucyl-L-glutaminyl-L-threonyl-L-tyrosyl-L-prolyl-L-arginyl-L-threonyl-L-asparaginyl-L-threonylglycyl-L-serylglycyl-L-threonyl-, cyclic (1→7)-disulfide
• Miacalcic
• Miacalcin
• Miadenil
• Prontocalcin
• Rulicalcin
• Salcatonin
• Salmon calcitonin I
• Salmon calcitonin-(1-32)
• Salmon Thyrocalcitonin
• Salmotonin
• Stalcin
• Tonocalcin
• Calcitonin(Salmone) Acetate

Calcitonin (salmon I)

CAS: 47931-85-1

Calcitonin inhibits osteoclast activity, lowers the blood calcium level, and positively influences bone mass density. Salmon calcitonin (sCT) is more potent than the human analog. sCT may act as an amylin agonist (Wielinga et al.). In animal studies, administration of sCT was shown to reduce food intake.

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Pureza: 99.3%

Forma y color: White Lyophilisate

Peso molecular: 3431.9

Ref: 01-4033011

CALCITONIN-GLY CRS

CAS: 115472-96-3, 47931-85-1

CALCITONIN-GLY CRS

Ref: 41-Y0000632

CALCITONIN (SALMON) CRS

CAS: 47931-85-1

CALCITONIN (SALMON) CRS

Fórmula: C₈H₆BrN

Peso molecular: 196.0439

Ref: 41-C0200000

Calcitonin Salmon

CAS: 47931-85-1

Polypeptide, protein and glycoprotein hormones, their derivatives and structural analogues, nesoi

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Forma y color: White Off-White Powder

Peso molecular: 3429.71331

Ref: 45-1086200

Calcitonin (Salmon)

CAS: 47931-85-1

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Peso molecular: 3431.90

Ref: 4Z-PC-322001

Calcitonin Salmon

CAS: 47931-85-1

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Pureza: >95.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 3,431.90

Ref: 3B-C3597

Calcitonin (salmon)

CAS: 47931-85-1

Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Pureza: 99.41% - 99.80%

Forma y color: Powder

Peso molecular: 3431.85

Ref: TM-TP1040

Calcitonin Acetate(Salmon)

CAS: 47931-85-1

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Pureza: 95%~99%

Forma y color: White to Off-white Powder

Peso molecular: 3431.85

Ref: BP-BPPG013

Calcitonin Salmon RS

CAS: 47931-85-1, 5989-81-1

Forma y color: White Solid

Ref: 2K-1039500021

Calcitonin, Salmon

CAS: 47931-85-1

Applications Calcitonin, Salmon is a calcium regulating hormone which exhibits hypocalcaemic and hypophosphatemic properties.

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Forma y color: Neat

Peso molecular: 3431.85

Ref: TR-C144558

N-Acetyl-cys(1)-calcitonin Salmon Trifluoroacetic Acid Salt

Producto controlado

CAS: 47931-85-1

Applications N-Acetyl-cys(1)-calcitonin Salmon is a derivative of Calcitonin (salmon), is a 32-amino acid linear polypeptide hormone that is produced in thyroid in humans. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).
References Boron, WF., et al.: Med. Physi., A Cellular and Molecular Approach (2004); Andreotti, G. et al.: J. Bio. Chem., 281, 24193 (2006);

Fórmula: C₁₄₇H₂₄₃N₄₄O₄₉S₂·x(C₂HF₃O₂)

Forma y color: Neat

Peso molecular: 3475.5911402

Ref: TR-A168465

Calcitonin (salmon) xAcetate

Producto controlado

CAS: 47931-85-1

Applications Calcitonin (salmon), is a 32-amino acid linear polypeptide hormone that is produced in thyroid in humans. It acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH).
References Boron, WF. et al.: Med. Phys., A Cellular and Molecular Approach (2004); Andreotti, G. et al.: J. Bio. Chem., 281, 24193 (2006);

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂·x(CH₃CO₂H)

Forma y color: Neat

Peso molecular: 3431.856005

Ref: TR-C144555

Calcitonin

CAS: 47931-85-1

Calcitonin is a peptide hormone that inhibits the release of calcium from bone, and decreases the blood level of calcium. Calcitonin is not active in the absence of parathyroid hormone (PTH) or vitamin D. It has been shown to inhibit the development of experimental myocardial infarcts in rats by inhibiting the release of calcium from bone, and has also been shown to have a protective effect on brain function. The calcitonin receptor is activated by binding with calcitonin, which then activates adenylyl cyclase and increases intracellular cAMP levels. This leads to increased activity at ATP-sensitive potassium channels, which causes hyperpolarisation of neurons. Caudate putamen neurons are particularly sensitive to calcitonin activity because they are rich in voltage-gated K+ channels that are sensitive to ATP-sensitive potassium channel activation. Calcitonin also plays a role in regulating serum Ca2+ concentration by inhib

Fórmula: C₁₄₅H₂₄₀N₄₄O₄₈S₂

Pureza: Min. 95%

Peso molecular: 3,431.86 g/mol

Ref: 3D-FC36651

Calcitonin (salmon)

CAS: 47931-85-1

Calcitonin (salmon)

Forma y color: White Powder

Ref: 47-355