CAS 480-36-4
:Linarina
Descripción:
Linarina, con el número CAS 480-36-4, es un glucósido flavonoide que se encuentra principalmente en varias plantas, particularmente en el género Lonicera, como la madreselva. Se caracteriza por su estructura química, que consiste en un esqueleto de flavona unido a una porción de azúcar, típicamente ramnosa o glucosa. Linarina exhibe varias actividades biológicas, incluyendo efectos antioxidantes, antiinflamatorios y potenciales efectos neuroprotectores, lo que lo convierte en un tema de interés en la investigación farmacológica. Sus propiedades de solubilidad están influenciadas por el enlace glucosídico, que puede afectar su biodisponibilidad e interacción con sistemas biológicos. Además, se ha estudiado Linarina por sus posibles aplicaciones terapéuticas, incluyendo su papel en la medicina tradicional. El compuesto es generalmente reconocido por su perfil de seguridad, aunque se necesitan más estudios para comprender completamente sus mecanismos de acción y eficacia en varios contextos de salud. En general, Linarina representa un compuesto significativo en el campo de los productos naturales y la fitoquímica, contribuyendo a la comprensión de las sustancias derivadas de plantas y sus beneficios para la salud.
Fórmula:C28H32O14
InChI:InChI=1S/C28H32O14/c1-11-21(31)23(33)25(35)27(39-11)38-10-19-22(32)24(34)26(36)28(42-19)40-14-7-15(29)20-16(30)9-17(41-18(20)8-14)12-3-5-13(37-2)6-4-12/h3-9,11,19,21-29,31-36H,10H2,1-2H3/t11-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
Clave InChI:InChIKey=YFVGIJBUXMQFOF-PJOVQGMDSA-N
SMILES:O=C1C=2C(OC(=C1)C3=CC=C(OC)C=C3)=CC(O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O)=CC2O
Sinónimos:- 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-
- 5-Hydroxy-4′-methoxyflavone-7-O-rutinoside
- 5-hydroxy-2-(4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside
- 7-[[6-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
- Acacetin 7-O-rutinoside
- Acacetin 7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnopyranosyl-(1→6)-β-<smallcap>D</span>-glucopyranoside
- Acacetin-7-O-(6′′-O-rhamnose)-β-<span class="text-smallcaps">D</span>-glucoside
- Acacetin-7-O-β-<span class="text-smallcaps">D</span>-rutinoside
- Acaciin
- Buddleoflavonoloside
- Buddleoside
- Linarigenin glycoside
- Linarin
- Linarine
- 7-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
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Se han encontrado 19 productos.
Linarin
CAS:Linarin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Fórmula:C28H32O14Pureza:(HPLC) ≥98%Forma y color:PowderPeso molecular:592.56Linarin
CAS:Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivativesFórmula:C28H32O14Forma y color:White PowderPeso molecular:592.17921Linarin
CAS:Fórmula:C28H32O14Pureza:(HPLC) ≥ 95.0%Forma y color:White to off-white or pale yellow powderPeso molecular:592.55Diosmin EP Impurity E (Linarin)
CAS:Fórmula:C28H32O14Forma y color:Pale Yellow To Off-White SolidPeso molecular:592.55Linarin (Standard)
CAS:Linarin (Standard) is a reference standard for research and analysis in studies involving Linarin. 1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.Fórmula:C28H32O14Forma y color:SolidPeso molecular:592.55Acaciin
CAS:Linarin is a flavone glycoside in the plants Flos chrysanthemi indici, Buddleja officinalis, Cirsium setosum, Mentha arvensis and Buddleja davidii, possesses analgesic, antipyretic, anti-inflammatory and neuroprotective activities.Fórmula:C28H32O14Pureza:95%~99%Forma y color:Yellow powderPeso molecular:592.55Linarin
CAS:Fórmula:C28H32O14Pureza:>95.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:592.55Linarin
CAS:Linarin inhibits acetylcholinesterase, reduces liver injury via TNF-α, protects neurons via PI3K/Akt, and has enhanced absorption with piperine.Fórmula:C28H32O14Pureza:97.95% - 98.27%Forma y color:White SolidPeso molecular:592.55Buddleoside
CAS:5-Hydroxy-2-(4-methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-oneFórmula:C28H32O14Pureza:98%Peso molecular:592.55Linarin
CAS:Natural glycosideFórmula:C28H32O14Pureza:≥ 90.0 % (HPLC)Forma y color:PowderPeso molecular:592.55Linarine
CAS:Producto controladoImpurity Diosmin EP Impurity E
Stability Hygroscopic
Applications Linarine (Diosmin EP Impurity E) is a naturally occurring flavone glycoside that was identified to possess potential sedative and anticonvulsant properties.
References Nugroho, A., et al.: Arch. Pharma. Res., 36, 51 (2013); Jung, H.A., et al.: Arch. Pharma. Res., 35, 1021 (2012); Shen, H.J., et al.: J. Med. Plants. Res., 5, 6555 (2011);Fórmula:C28H32O14Forma y color:NeatPeso molecular:592.545Linarin
CAS:Linarin is a naturally occurring flavonoid compound, which is primarily extracted from plant sources such as the leaves of *Buddleja davidii* and *Mentha aquatica*. This flavonoid is notable for its biological activity, which is characterized by its interaction with various enzymes and receptors involved in cellular processes.Fórmula:C28H33O14Pureza:Min. 95%Forma y color:PowderPeso molecular:593.55 g/mol
