CAS 524-17-4

Dauricina

Descripción:

Dauricina, con el número CAS 524-17-4, es un alcaloide derivado de varias especies de plantas, particularmente aquellas de la familia Menispermaceae. Es conocido por su complejidad estructural, que presenta un marco tetracíclico que contribuye a su actividad biológica. Dauricina exhibe una variedad de propiedades farmacológicas, incluyendo efectos analgésicos, antiinflamatorios y potenciales antitumorales, lo que lo convierte en un interés en la química medicinal. El compuesto se encuentra típicamente en forma de un sólido cristalino blanco a amarillo pálido y es soluble en disolventes orgánicos como el etanol y el cloroformo, pero menos soluble en agua. Se piensa que su mecanismo de acción implica la modulación de sistemas de neurotransmisores y la interferencia con las vías de señalización celular. Debido a su naturaleza bioactiva, la investigación continúa sobre su potencial terapéutico y perfil de seguridad, aunque se necesitan más estudios para comprender completamente su eficacia y mecanismos en varios contextos biológicos. Al igual que con muchos alcaloides, se aconseja precaución respecto a su uso, ya que puede exhibir toxicidad a concentraciones más altas.

Fórmula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3

Clave InChI: InChIKey=AQASRZOCERRGBL-ROJLCIKYSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(OC)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3

Sinónimos:

• 4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]-2-{4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenoxy}Phenol
• 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-(4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenoxy)phenol
• Nsc 36413
• Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-
• Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-
• Dauricine
• 6,6'-Di-O-Methyldauricoline
• Menispermum dauricum DC Extract
• (r-(r*,r*))-y)
• -(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenox
• dauricine (8ci)

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.77

Ref: 7W-GP0181

Dauricine

CAS: 524-17-4

Dauricine

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99.5%

Peso molecular: 624.77

Ref: 54-BUP07831

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98%

Forma y color: Solid

Peso molecular: 624.7658

Ref: IN-DA00DEJ0

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 95%~99%

Peso molecular: 624.778

Ref: BP-BP0452

Dauricine (Standard)

CAS: 524-17-4

Dauricine (Standard) is a reference standard for research and analysis in studies involving Dauricine. 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.77

Ref: TM-TMSM-0845

Dauricine

Producto controlado

CAS: 524-17-4

Applications Dauricine is a bisbenzylisoquinoline allkaloid derivative that displays a noted number of pharmaceutical properties. It is known to induces severe lung toxicity in animals.
References Xie, H. et al.: Anal. Bioanal. Chem., 408, 4111 (2016);

Fórmula: C₃₈H₄₄N₂O₆

Forma y color: Neat

Peso molecular: 624.77

Ref: TR-D194825

Dauricine

CAS: 524-17-4

1.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 99.24% - 99.75%

Forma y color: Solid

Peso molecular: 624.7658

Ref: TM-T6S0119

Dauricine

CAS: 524-17-4

Natural alkaloid

Fórmula: C₃₈H₄₄N₂O₆

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 624.78

Ref: 5G-80419

Dauricine

CAS: 524-17-4

Dauricine is a natural bisbenzylisoquinoline alkaloid, which is derived from the plant Menispermum dauricum, commonly found in regions of Asia. Its mode of action involves inhibition of various ion channels, notably the calcium and potassium channels, as well as modulation of signaling pathways that influence cell proliferation and apoptosis. These biochemical activities endow Dauricine with the potential to influence cardiovascular, neurological, and oncological outcomes.

Fórmula: C₃₈H₄₄N₂O₆

Pureza: Min. 95%

Forma y color: Brown Yellow Powder

Peso molecular: 624.77 g/mol

Ref: 3D-FD66056

Dauricine

CAS: 524-17-4

Fórmula: C₃₈H₄₄N₂O₆

Peso molecular: 624.8

Ref: BE-RMT10620

Dauricine

CAS: 524-17-4

4-(((R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-2-(4-(((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenoxy)phenol

Fórmula: C₃₈H₄₄N₂O₆

Pureza: 98%

Peso molecular: 624.77

Ref: IN-DG123496

DAURICINE

CAS: 524-17-4

Pureza: 98%

Peso molecular: 624.7780151

Ref: 10-F794658