CAS 526-08-9
:Sulfafenazol
Descripción:
Sulfafenazol es un antibiótico sulfonamida que pertenece a la clase de compuestos conocidos como fármacos sulfa. Se caracteriza por su capacidad para inhibir el crecimiento bacteriano al interferir con la síntesis de ácido fólico, que es esencial para el metabolismo bacteriano. La estructura química de Sulfafenazol presenta un grupo sulfonamida unido a un anillo fenilo, lo que contribuye a sus propiedades antibacterianas. Se utiliza típicamente en el tratamiento de infecciones del tracto urinario y otras infecciones bacterianas. Sulfafenazol es conocido por su relativamente baja solubilidad en agua, lo que puede afectar su biodisponibilidad y eficacia terapéutica. El compuesto se administra generalmente por vía oral y se metaboliza en el hígado, con sus metabolitos excretados principalmente a través de la orina. Además, Sulfafenazol puede presentar efectos secundarios, incluyendo reacciones alérgicas y trastornos hematológicos, lo que requiere un monitoreo cuidadoso durante el tratamiento. En general, Sulfafenazol sigue siendo un agente importante en el arsenal de antibióticos, particularmente en escenarios clínicos específicos donde su uso está justificado.
Fórmula:C15H14N4O2S
InChI:InChI=1S/C15H14N4O2S/c16-12-6-8-14(9-7-12)22(20,21)18-15-10-11-17-19(15)13-4-2-1-3-5-13/h1-11,18H,16H2
Clave InChI:InChIKey=QWCJHSGMANYXCW-UHFFFAOYSA-N
SMILES:N(S(=O)(=O)C1=CC=C(N)C=C1)C=2N(N=CC2)C3=CC=CC=C3
Sinónimos:- 1-Phenyl-5-sulfanilamidopyrazole
- 2-Phenyl-3-sulfanilamidopyrazole
- 3-(p-Aminobenzenesulfonamido)-2-phenylpyrazole
- 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
- 5-Sulfanilamido-1-phenylpyrazole
- Benzenesulfonamide, 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)-
- Depocid
- Depotsulfonamide
- Eftolon
- Firmazolo
- Inamil
- Isarol
- Isarol V
- Merian
- Microtan pirazolo
- N1-(1-phenylpyrazol-5-yl)sulphanilamide
- N<sup>1</sup>-(1-Phenylpyrazol-5-yl)sulfanilamide
- Orisul
- Orisulf
- Paidazolo
- Plisulfan
- Raziosulfa
- Sulfabid
- Sulfanilamide, N<sup>1</sup>-(1-phenylpyrazol-5-yl)-
- Sulfaphenazol
- Sulfaphenazon
- Sulfaphenylpyrazole
- Sulphaphenazole
- Ver más sinónimos
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Encontrado 15 productos.
Sulfaphenazole
CAS:Fórmula:C15H14N4O2SPureza:≥ 98.0%Forma y color:White to off-white powderPeso molecular:314.364-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide
CAS:<p>4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide</p>Fórmula:C15H14N4O2SPureza:99%Forma y color: pale yellow solidPeso molecular:314.37g/molMinistry of Agriculture Veterinary Drug Mixture 348 10 µg/mL in Acetonitrile:Water
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Forma y color:ColourlessSulfaphenazole
CAS:Fórmula:C15H14N4O2SPureza:>95.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:314.36Sulfaphenazole 100 µg/mL in Acetonitrile
CAS:Fórmula:C15H14N4O2SForma y color:Single SolutionPeso molecular:314.36Sulfaphenazole
CAS:<p>Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for</p>Fórmula:C15H14N4O2SPureza:97.53% - 99.67%Forma y color:SolidPeso molecular:314.36Sulfaphenazole-d4
CAS:Producto controlado<p>Applications Sulfaphenazole-d4 is the labelled analogue of Sulfaphenazole (S689020), that is used as an inhibitor for mammalian CYP2C9, an enzyme of the cytochrome P450 family, allowing for pharmacological application.Sulfaphenazole can help protect against ischemia-reperfusion, and resulting tissue damage through inhibition of CYP2C9.<br>References Vestergren, A.L.S. et al.: Mol. Biol. Rep., 39, 6867 (2012); Huang, C. et al.: Amer. J. Phys., 298, H570 (2010);<br></p>Fórmula:C15H10D4N4O2SForma y color:Off-WhitePeso molecular:318.39Sulfaphenazole
CAS:Producto controlado<p>Applications Sulfaphenazole is used as an inhibitor for mammalian CYP2C9, an enzyme of the cytochrome P450 family allowing for pharmacological application.Sulfaphenazole can help protect against ischemia-reperfusion, and resulting tissue damage by inhibition of CYP2C9.<br>References Vestergren, A.L.S. et al.: Mol. Biol. Rep., 39, 6867 (2012); Huang, C. et al.: Amer. J. Phys., 298, H570 (2010);<br></p>Fórmula:C15H14N4O2SForma y color:Off WhitePeso molecular:314.36Sulfaphenazole
CAS:<p>Sulfaphenazole is an antibacterial drug that belongs to the group of sulfonamides. It inhibits bacterial growth by competitively inhibiting the synthesis of folic acid in bacteria, which is required for protein synthesis and cell division. Sulfaphenazole has been shown to inhibit a number of enzymes, such as P450 activity, catalysed by cytochrome P450 enzymes. It also inhibits the mitochondrial membrane potential, which is vital for oxidative phosphorylation. Sulfaphenazole has shown inhibitory properties against kidney fibrosis and may be useful in treating kidney failure due to diabetes or hypertension. This drug is also used as an oral hypoglycaemic agent and to treat complications from myocardial infarcts such as autophagy.</p>Fórmula:C15H14N4O2SPureza:Min. 95%Forma y color:PowderPeso molecular:314.36 g/mol4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
CAS:Fórmula:C15H14N4O2SPureza:95.0%Forma y color:SolidPeso molecular:314.36
