CAS 548-19-6

Isoginkgetina

Descripción:

Isoginkgetina, con el número CAS 548-19-6, es un compuesto flavonoide derivado principalmente de la planta Ginkgo biloba. Se conoce por sus posibles propiedades farmacológicas, incluyendo efectos antioxidantes, antiinflamatorios y neuroprotectores. Isoginkgetina exhibe una estructura química única caracterizada por múltiples grupos hidroxilo, que contribuyen a su reactividad y actividad biológica. Este compuesto se estudia a menudo por su papel en la medicina tradicional y sus posibles aplicaciones terapéuticas en condiciones como enfermedades neurodegenerativas y trastornos cardiovasculares. Además, se ha investigado Isoginkgetina por su capacidad para modular diversas vías de señalización, lo que puede aumentar su eficacia en la promoción de la salud. Su solubilidad en disolventes orgánicos y su limitada solubilidad en agua son características importantes que influyen en su biodisponibilidad y formulación en aplicaciones farmacéuticas. En general, Isoginkgetina representa un área significativa de interés en la fitoquímica y la farmacología, destacando la importancia de los compuestos naturales en el descubrimiento y desarrollo de fármacos.

Fórmula: C₃₂H₂₂O₁₀

InChI: InChI=1/C32H22O10/c1-39-18-6-3-15(4-7-18)26-14-24(38)31-22(36)12-21(35)29(32(31)42-26)19-9-16(5-8-25(19)40-2)27-13-23(37)30-20(34)10-17(33)11-28(30)41-27/h3-14,33-36H,1-2H3

Clave InChI: InChIKey=HUOOMAOYXQFIDQ-UHFFFAOYSA-N

SMILES: OC=1C(=C2C(C(=O)C=C(O2)C3=CC=C(OC)C=C3)=C(O)C1)C4=CC(=CC=C4OC)C=5OC=6C(C(=O)C5)=C(O)C=C(O)C6

Sinónimos:

• 3′′′,8-Biflavone, 5,5′′,7,7′′-tetrahydroxy-4′,4′′′-dimethoxy-
• 4H-1-Benzopyran-4-one, 8-[5-(5,7-dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-
• 4′,4′′′-Dimethylamentoflavone
• 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
• Isoginkgetin
• ISOGINKGETIN(SH)
• 2-(4-Methoxyphenyl)-5,7-dihydroxy-8-[2-methoxy-5-(4-oxo-5,7-dihydroxy-4H-1-benzopyran-2-yl)phenyl]-4H-1-benzopyran-4-one
• 4',4'''-Dimethoxyamentoflavone
• 3''',8-Biflavone, 5,5'',7,7''-tetrahydroxy-4',4'''-dimethoxy-
• 2-(4-Methoxyphenyl)-8-[6-methoxy-3-(4-oxo-5,7-dihydroxy-4H-1-benzopyran-2-yl)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one
• 8-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-methoxyphenyl]-5,7-dihydroxy-2-(4-methoxyphenyl)chromen-4-one
• ISOGINKGETIN(RG)(PLEASE CALL)
• 5,5'',7,7''-Tetrahydroxy-4',4'''-dimethoxy-3''',8-biflavone
• Isoginkgetin, >99%
• 4',4'''-Dimethylamentoflavone

Isoginkgetin

CAS: 548-19-6

Fórmula: C₃₂H₂₂O₁₀

Pureza: >95.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 566.52

Ref: 3B-I1296

ISOGINKGETIN

CAS: 548-19-6

ISOGINKGETIN

Fórmula: C₃₂H₂₂O₁₀

Pureza: ≥98%

Peso molecular: 566.51

Ref: 54-BUP16404

Isoginkgetin

CAS: 548-19-6

Fórmula: C₃₂H₂₂O₁₀

Peso molecular: 566.52

Ref: 7W-GY7715

ISOGINKGETIN (Standard)

CAS: 548-19-6

ISOGINKGETIN (Standard) is a reference standard for research and analysis in studies involving ISOGINKGETIN. 1. ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. 2. Isoginkgetin has anti-tumor activity, the mechanistic basis is splicing inhibition , thus, pre-mRNA splicing inhibitors may represent a novel avenue for development of new anti-cancer agents.3. Isoginkgetin can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression. 4. Isoginkgetin (0.3mg/kg ip for 3d) can reduce the level of O2·- in plasma and erythroeyte and sometimes increase the activity of SOD in anoxic rats, the action being stronger than aspirin.

Fórmula: C₃₂H₂₂O₁₀

Peso molecular: 566.5111

Ref: TM-TMSM-3042

Isoginkgetin

CAS: 548-19-6

Fórmula: C₃₂H₂₂O₁₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 566.5111

Ref: IN-DA00DBAS

Isoginkgetin

CAS: 548-19-6

Isoginkgetin is a MMP-9 inhibitor, also a pre-mRNA splicing inhibitor with IC 50 of 30 uM. Isoginkgetin can up-regulate adiponectin secretion with potency comparable to that of rosiglitazone, a known modulator of adiponectin production. Isoginkgetin has anti-tumor activity, it can inhibit tumor cell invasion by regulating phosphatidylinositol 3-kinase/Akt-dependent matrix metalloproteinase-9 expression.

Fórmula: C₃₂H₂₂O₁₀

Pureza: 95%~99%

Peso molecular: 566.518

Ref: BP-BP0784

Isoginkgetin

CAS: 548-19-6

ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.

Fórmula: C₃₂H₂₂O₁₀

Pureza: 98% - 99.75%

Forma y color: Yellow Solid

Peso molecular: 566.5111

Ref: TM-T4S21320

Isoginkgetin

CAS: 548-19-6

8-(5-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Fórmula: C₃₂H₂₂O₁₀

Pureza: 98%

Peso molecular: 566.51

Ref: IN-DG298243

Isoginkgetin

CAS: 548-19-6

Oxygen-heterocyclic compound

Fórmula: C₃₂H₂₂O₁₀

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 566.52

Ref: 5G-83513

Isoginkgetin

CAS: 548-19-6

Fórmula: C₃₂H₂₂O₁₀

Forma y color: Solid

Peso molecular: 566.5

Ref: BE-RMT22104

ISOGINKGETIN

CAS: 548-19-6

Pureza: 98%

Peso molecular: 566.5180054

Ref: 10-F814500