CAS 55268-74-1
:Praziquantel
Descripción:
Praziquantel es un agente anthelmintico sintético utilizado principalmente para tratar infecciones parasitarias causadas por esquistosomas y otros gusanos planos. Se caracteriza por su fórmula química, que incluye una estructura bicíclica única que contribuye a su eficacia. Praziquantel se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la administración. La sustancia exhibe un amplio espectro de actividad contra varios trematodos y cestodos, lo que lleva a un aumento de la permeabilidad de las membranas celulares del parásito, resultando en parálisis y muerte del organismo. Praziquantel generalmente es bien tolerado, con efectos secundarios que son leves y transitorios, como dolor de cabeza o trastornos gastrointestinales. Su farmacocinética implica un extenso metabolismo en el hígado, y se excreta principalmente a través de la orina. El compuesto está clasificado en la Lista de Medicamentos Esenciales de la Organización Mundial de la Salud, destacando su importancia en la salud global, particularmente en regiones donde las infecciones parasitarias son endémicas.
Fórmula:C19H24N2O2
InChI:InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2
Clave InChI:InChIKey=FSVJFNAIGNNGKK-UHFFFAOYSA-N
SMILES:O=C1N2C(C=3C(CC2)=CC=CC3)CN(C(=O)C4CCCCC4)C1
Sinónimos:- (±)-Praziquatel
- 2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one
- 2-(Cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one
- 2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one
- 2-Cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one
- 2-Cyclohexyl-carbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazine(2,1-a)isoquinoline-4-one
- 4H-Pyrazino(2,1-A)Isoquinolin-4-One,2-(Cyclohexylcarbonyl)-1,2,3,6,7,11B-Hexah
- 4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-
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- Ver más sinónimos
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Praziquantel
CAS:Fórmula:C19H24N2O2Pureza:>98.0%(HPLC)(N)Forma y color:White to Almost white powder to crystalPeso molecular:312.41Praziquantel, 98%
CAS:Praziquantel, 98%; Used against schistosome and many cestode infestations. It is used to study voltage-gated Ca2+ channels and is a potential small molecule neurogenic.Fórmula:C19H24N2O2Pureza:98%Peso molecular:312.41PRAZIQUANTEL FOR SYSTEM SUITABILITY CRS
CAS:PRAZIQUANTEL FOR SYSTEM SUITABILITY CRSFórmula:C19H24N2O2Peso molecular:312.4061PRAZIQUANTEL CRS
CAS:PRAZIQUANTEL CRSFórmula:C19H24N2O2Forma y color:Crystalline Powder. White. Powder., Crystalline Powder. White. Powder.Peso molecular:312.4061Praziquantel
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFórmula:C19H24N2O2Forma y color:White PowderPeso molecular:312.18378Ref: IN-DA0035UL
5kgA consultar10kgA consultar5g23,00€10g28,00€15g37,00€25g43,00€50g62,00€75g72,00€100g72,00€250g127,00€500g151,00€1000g170,00€1kg179,00€5000g595,00€Praziquantel
CAS:Praziquantel (Droncit) is an anthelmintic that paralyzes worms by increasing calcium in muscle cells, causing tegument damage and immune response.Fórmula:C19H24N2O2Pureza:99.67% - 99.69%Forma y color:SolidPeso molecular:312.41Praziquantel
CAS:Fórmula:C19H24N2O2Pureza:98.5 - 101.0 % (dried basis)Forma y color:White to off-white crystalline powderPeso molecular:312.41Praziquantel 100 µg/mL in Acetonitrile
CAS:Fórmula:C19H24N2O2Forma y color:Single SolutionPeso molecular:312.41Praziquantel (Standard)
CAS:Praziquantel (Standard) is the standard substance of Praziquantel, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.41Praziquantel
CAS:2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-oneFórmula:C19H24N2O2Pureza:98%Peso molecular:312.41Praziquantel
CAS:Applications Anthelmintic, effective against flatworms.
References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),Fórmula:C19H24N2O2Forma y color:NeatPeso molecular:312.41Praziquantel
CAS:Anti-schistosomal; sensory transient receptor potential melastatin type 8 agonist
Fórmula:C19H24N2O2Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:312.41 g/mol
