CAS 56-75-7

(-)-Cloranfenicol

Descripción:

(-)-Cloranfenicol, con el número CAS 56-75-7, es un antibiótico de amplio espectro derivado originalmente de la bacteria Streptomyces venezuelae. Se caracteriza por su capacidad para inhibir la síntesis de proteínas bacterianas al unirse a la subunidad 50S del ribosoma bacteriano, bloqueando efectivamente la formación de enlaces peptídicos. Este compuesto es un polvo cristalino blanco a blanco sucio que es soluble en agua y alcohol, pero tiene una solubilidad limitada en disolventes orgánicos. Su fórmula molecular es C11H12Cl2N2O5, y tiene un peso molecular de aproximadamente 323.13 g/mol. (-)-Cloranfenicol exhibe actividad antibacteriana contra una amplia gama de bacterias Gram-positivas y Gram-negativas, lo que lo hace útil en el tratamiento de diversas infecciones. Sin embargo, su uso está limitado debido a posibles efectos secundarios, incluyendo anemia aplásica y síndrome del bebé gris en recién nacidos. Como resultado, a menudo se reserva para infecciones graves donde otros antibióticos son ineficaces. El manejo y la dosificación adecuados son cruciales para minimizar los efectos adversos y garantizar la eficacia terapéutica.

Fórmula: C₁₁H₁₂Cl₂N₂O₅

InChI: InChI=1/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9?/m1/s1

Clave InChI: InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CO)(O)C1=CC=C(N(=O)=O)C=C1

Sinónimos:

• 2,2-Dichloro-N-(2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl)-Acetamid
• 2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-Dichloro-N-[2-Hydroxy-1-(Hydroxymethyl)-2-(4-Nitrophenyl)Ethyl]Acetamide
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• 2,2-dichloro-N-[(1R,2S)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• 2,2-dichloro-N-[(1S,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
• Ak-Chlor
• Alficetyn
• Amphenicol
• Amphicol
• Amseclor
• Anacetin
• Aquamycetin
• Austracol
• Bradyoxetin
• CAF
• CAM
• CAP
• CPh
• Catilan
• Chemicetin
• Chemicetina
• Chlomycol
• Chloramex
• Chloramphenicol
• Chloramsaar
• Chlorasol
• Chlorcetin
• Chloricol
• Chlorocaps
• Chlorocid
• Chlorocide
• Chlorocin
• Chloromycetin
• Chloronitrin
• Chloroptic
• Ciplamycetin
• Cloramfen
• Cloramfenicol
• Cloramficin
• Cloramicol
• Clorocyn
• Cloromisan
• Cylphenicol
• D-(-)-Chloramphenicol
• D-(-)-Threo-2,2-Dichloro-N-[Beta-Hydroxy-Alpha-(Hydroxy-Methyl)-P-Nitrophenethyl]Acetamide
• D-(-)-threo-1-(4-Nitrophenyl)-2-dichloroacetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloracetamido-1,3-propanediol
• D-(-)-threo-1-p-Nitrophenyl-2-dichloroacetylamino-1,3-propanediol
• D-(-)-threo-2-Dichloroacetamido-1-p-nitrophenyl-1,3-propanediol
• D-(-)-threo-Chloramphenicol
• D-threo-(1R,2R)-1-p-Nitrophenyl-2-dichloroacetamido-1,3-propanediol
• D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol
• Detreomycin
• Embacetin
• Enicol
• Enteromycetin
• Farmicetina
• Fenicol
• Globenicol
• Gloveticol
• Halcetin
• Intramycetin
• Ismicetina
• Juvamycetin
• Kamaver
• Kemicetine
• Klorita
• Leukomyan
• Leukomycin
• Levocin
• Levomicetina
• Levomitsetin
• Levomycetin
• Levoplast
• Levosin
• Levovetin
• Loromisin
• Mastiphen
• Micloretin
• Micoclorina
• Microcetina
• Mychel
• Mychel-Vet
• Mycinol
• Myclocin
• Mycochlorin
• Novomycetin
• Ocuphenicol
• Opclor
• Ophthochlor
• Pantovernil
• Paraxin
• Quemicetina
• Ronphenil
• Septicol
• Sintomicetin
• Sintomicetina
• Soluthor
• Stanomycetin
• Synthomycetin
• Synthomycin
• Tevcocin
• Tifomycine
• Treomicetina
• Unimycetin
• Veticol
• Viceton
• [R-(R*,R*)]-2,2-Dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide
• D,L-chloramphenicol
• Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-
• nitrophenyl)ethyl]acetamide
• Acetamide, 2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-
• Acetamide, 2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
• 2,2-dichloro-N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-(4-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENETHYL]ACETAMIDE
• D-THREO-(-)-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-HYDROXYMETHYL-P-NITROPHENETHYL]ACETAMIDE
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-4-NITROPHENYL] ACETAMIDE
• D-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• D-2-DICHLOROACETAMIDO-1-P-NITRO-PHENYL-1,3-PROPANEDIOL
• [R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE
• D(-)-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA-(HYDROXY-METHYL)-P-NITROPHENYLETHYL]ACETAMIDE
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL
• CHLORAMPHENICOLUM
• D-(-)-THREO-2-DICHLOROACETAMIDO-1-[P-NITRO-PHENYL]-1,3-PROPANEDIOL
• ,[theta-(theta,theta)]-
• D-THREO-2,2-DICHLORO-N-[BETA-HYDROXY-ALPHA(HYDROXYMETHYL)-BETA-(4-NITROPHENYL)ETHYL]ACETAMIDE

Chloramphenicol

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Peso molecular: 323.13

Ref: 4Z-C-10102

Chloramphenicol, USP grade

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 97.0 - 103.0 %

Forma y color: White to light-yellow crystalline powder

Peso molecular: 323.14

Ref: 7W-GA0505

Chloramphenicol

CAS: 56-75-7

Chloramphenicol

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: >99%

Forma y color: solid

Peso molecular: 323.13g/mol

Ref: 54-BIC0113

Chloramphenicol (10mg/ml)

CAS: 56-75-7

Chloramphenicol (10mg/ml)

Forma y color: Solution

Peso molecular: 323.13g/mol

Ref: 54-BIG1028

Chloramphenicol-d5

Producto controlado

CAS: 56-75-7

Applications Chloramphenicol-d5, is the labeled analogue of Chloramphenicol (C325030), which has a broad spectrum of activity against Gram-positive and gram-negative bacteria. It is also antibacterial, and antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Fórmula: C₁₁H₇D₅Cl₂N₂O₅

Forma y color: Off-White

Peso molecular: 328.16

Ref: TR-C325033

Chloramphenicol

Producto controlado

CAS: 56-75-7

Applications Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Forma y color: Neat

Peso molecular: 323.13

Ref: TR-C325030

Chloramphenicol-d5 (100Mug/mL in Acetonitrile)

Producto controlado

CAS: 56-75-7

Fórmula: C₁₁H₇D₅Cl₂N₂O₅

Forma y color: Colourless

Peso molecular: 328.16

Ref: TR-KIT8327

Chloramphenicol

CAS: 56-75-7

Chloramphenicol is produced by Streptomyces venezuelae. It is a broad-spectrum antibiotic with bacteriostatic properties. It interferes with bacterial protein synthesis by reversibly binding to the 50S ribosome unit. Used as substrate in the CAT (chloramphenicol acetyl transferase) assay, where the CAT gene expression is monitored by the ability of a system to transform chloramphenicol into acetyl chloramphenicol, which can be followed by simple thin layer chromatography. It is employed in VTM to prevent bacterial growth during specimen storage and transportation.

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 323.13 g/mol

Ref: 3D-AC09460

Chloramphenicol (CFP) for tissue culture, 98-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 98 - 102%

Forma y color: White to pale yellow, Crystalline powder, Clear

Peso molecular: 323.1

Ref: SR-28812

Chloramphenicol (CFP), 98-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: min. 98-102%

Forma y color: White to pale yellow, Crystalline powder, Clear

Peso molecular: 323.1

Ref: SR-97686

Chloramphenicol cell culture, 99%, Endotoxin (BET) 0.2 EU/mg

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Peso molecular: 323.1

Ref: SR-17796

Chloramphenicol (CFP) ExiPlus, Multi-Compendial, 98.0-102%

CAS: 56-75-7

Fórmula: C₁₁H₁₂Cl₂N₂O₅

Pureza: 98.0-102%

Forma y color: White to pale yellow, Crystalline powder or fine crystals, Clear

Peso molecular: 323.1

Ref: SR-57956