CAS 56602-33-6

reactivo BOP

Descripción:

reactivo BOP, o benzotriazol-1-il-oxi-tris(dimetilamino)fosfonio hexafluorofosfato, es un compuesto químico comúnmente utilizado en síntesis orgánica, particularmente en reacciones de acilo de péptidos. Sirve como un agente de acilo que facilita la formación de enlaces amida entre ácidos carboxílicos y aminas. reactivo BOP se caracteriza por su capacidad para activar ácidos carboxílicos, haciéndolos más reactivos hacia el ataque nucleofílico por aminas. Este reactivo se prefiere típicamente por sus condiciones de reacción suaves y compatibilidad con varios grupos funcionales, lo que minimiza las reacciones secundarias. Es un sólido blanco a blanco sucio que es soluble en disolventes orgánicos polares. Se deben observar precauciones de seguridad al manipular reactivo BOP, ya que puede ser peligroso y puede causar irritación. El almacenamiento adecuado en un lugar fresco y seco, alejado de la humedad y sustancias incompatibles, es esencial para mantener su estabilidad y efectividad en aplicaciones sintéticas.

Fórmula: C₁₂H₂₂N₆OP·F₆P

InChI: InChI=1S/C12H22N6OP.F6P/c1-15(2)20(16(3)4,17(5)6)19-18-12-10-8-7-9-11(12)13-14-18;1-7(2,3,4,5)6/h7-10H,1-6H3;/q+1;-1

Clave InChI: InChIKey=MGEVGECQZUIPSV-UHFFFAOYSA-N

SMILES: [P+](ON1C=2C(N=N1)=CC=CC2)(N(C)C)(N(C)C)N(C)C.[P+5]([F-])([F-])([F-])([F-])([F-])[F-]

Sinónimos:

• (1H-benzotriazol-1-yloxy)[tris(dimethylamino)]phosphonium hexafluorophosphate
• (Benzotriazol-1-yloxy)tris(dimethylamino) hexafluorophosphate
• (Boranyloxy)Phosphane
• 1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate
• 1H-Benzotriazole, 1-hydroxy-, phosphorus complex
• 2-(1H-Benzotriazol-1-yl)tris(dimethylamino)phosphonium hexafluorophosphate
• BOP
• BOP hexafluorophosphate
• BOP reagent
• Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate
• Benzotriazol-1-yloxytris(dimethylamino)-phosphonium hexafluorophosphate
• Castro reagent
• Castro's reagent
• Le BOP
• Methanamine, N-methyl-, phosphorus complex
• Phosphate(1-), hexafluoro-, (T-4)-(1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)phosphorus(1+)
• Phosphorus(1+), (1-hydroxy-1H-benzotriazolato-O)tris(N-methylmethanaminato)-, (T-4)-, hexafluorophosphate(1-)

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate [Coupling Reagent for Peptide]

CAS: 56602-33-6

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 442.29

Ref: 3B-B1651

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate, 98%

CAS: 56602-33-6

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecarobox

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: 98%

Forma y color: Crystalline powder, White

Peso molecular: 442.29

Ref: 02-A16140

[(1H-Benzotriazol-1-yl)oxy]tris(dimethylamino)phosphonium hexafluorophosphate

CAS: 56602-33-6

[(1H-Benzotriazol-1-yl)oxy]tris(dimethylamino)phosphonium hexafluorophosphate

Fórmula: C₁₂H₂₂N₆OP·PF₆

Pureza: ≥95%

Forma y color: Solid-Powder

Peso molecular: 442.28062

Ref: 54-PC2519

(Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate

CAS: 56602-33-6

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 442.2806

Ref: IN-DA0032D4

Benzotriazol-1-yl-oxy-tris(dimethylamino) phosphonium hexafluorophosphate (BOP Reagent)

CAS: 56602-33-6

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: ≥ 98.0%

Forma y color: White to beige or light-yellow powder to crystals

Peso molecular: 442.29

Ref: 7W-GE5235

BOP Reagent

CAS: 56602-33-6

((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tris(dimethylamino)phosphonium hexafluorophosphate(V)

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: 98%

Peso molecular: 442.28

Ref: IN-DG21506

BOP Reagent

CAS: 56602-33-6

BOP Reagent is a reagent that reacts with the phosphate group of dinucleotide phosphates, such as those found in DNA and RNA. It can be used for structural analysis and to determine the presence of nucleic acids in human serum or other biological samples. The BOP Reagent binds to the phosphate group by means of intramolecular hydrogen bonding. This reaction generates a transient, covalently-bound enzyme-substrate complex that can be detected by fluorescence probe.

Fórmula: C₁₂H₂₂N₆OF₆P₂

Pureza: Min. 95%

Peso molecular: 442.29 g/mol

Ref: 3D-KBP-1060-PI

BOP

CAS: 56602-33-6

BOP, also known with the name of Castro’s reagent, is a phosphonium coupling reagent used for peptide synthesis. BOP can be employed in presence of a base such as triethylamine or Hünig’s base and forms HOBt in situ, which then generates an activated ester. BOP is a very effective coupling reagent, achieving high yields, low epimerisation and high conversion rates. However, it forms the extremely toxic and carcinogenic HMPA in situ, therefore the equally efficient pyrrolidino derivative PyBOP was introduced, which leads to a less toxic by-product.

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: Min. 98 Area-%

Forma y color: White Off-White Powder

Peso molecular: 442.28 g/mol

Ref: 3D-FB01762

Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate

CAS: 56602-33-6

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: 98.0%

Forma y color: Solid

Peso molecular: 442.287

Ref: 10-F009018

Benzotriazol-1-yloxytris(dimethylamino)phosphonium Hexafluorophosphate

Producto controlado

CAS: 56602-33-6

Applications A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kenner, G.W., Seely, J., J. Am. Chem. Soc., 94, 3259 (1972), Castro, B., et al.: Tetrahedron Lett., 1219 (1975)

Fórmula: C₁₂H₂₂N₆OP·F₆P

Forma y color: Neat

Peso molecular: 442.28

Ref: TR-B207000

BOP Reagent extrapure AR, 98%

CAS: 56602-33-6

Fórmula: C₁₂H₂₂F₆N₆OP₂

Pureza: min. 98.0%

Forma y color: White to pale yellow, Crystalline powder, Crystalline powder

Peso molecular: 442.29

Ref: SR-59946