CAS 567-03-3

Tetrahydrodeoxicorticosterona

Descripción:

Tetrahydrodeoxicorticosterona (THDOC) es una hormona esteroide que pertenece a la clase de los corticosteroides. Es un metabolito de la desoxicorticosterona y se produce principalmente en las glándulas suprarrenales. THDOC juega un papel en la regulación del equilibrio de electrolitos y se ha implicado en varios procesos fisiológicos, incluida la modulación de la presión arterial y la respuesta al estrés. La sustancia se caracteriza por su estructura esteroide de cuatro anillos, que es típica de los corticosteroides, y exhibe actividad tanto mineralocorticoide como glucocorticoide, aunque en menor medida que otros corticosteroides como el cortisol. Se sabe que THDOC interactúa con los receptores mineralocorticoides, influyendo en el equilibrio de sodio y potasio en el cuerpo. Además, se ha estudiado por sus posibles propiedades neuroactivas, ya que puede cruzar la barrera hematoencefálica y puede afectar el estado de ánimo y el comportamiento. Debido a su naturaleza hormonal, THDOC está sujeto a regulación en varios contextos, particularmente en deportes y medicina, donde su uso puede ser monitoreado para mejorar el rendimiento o con fines terapéuticos.

Fórmula: C₂₁H₃₄O₃

InChI: InChI=1S/C21H34O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h13-18,22-23H,3-12H2,1-2H3/t13-,14-,15+,16+,17+,18-,20+,21+/m1/s1

Clave InChI: InChIKey=CYKYBWRSLLXBOW-DATPGIFZSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@H]2C(CO)=O)[H]

Sinónimos:

• (3Alpha,5Alpha)-3,21-Dihydroxypregnan-20-One
• (3Alpha,5Beta)-3,21-Dihydroxypregnan-20-One
• (3α,5β)-3,21-Dihydroxypregnan-20-one
• 21-Hydroxypregnanolone
• 3alpha,21-Dihydroxy-5beta-pregnan-20-one
• 3α,21-Dihydroxy-5β-pregnan-20-one
• 3α,5β-Tetrahydrodeoxycorticosterone
• 5β-Pregnan-20-one, 3α,21-dihydroxy-
• 5β-Pregnan-3α,21-diol-20-one
• Corticosterone, 11-deoxytetrahydro-
• Corticosterone, deoxytetrahydro-
• Deoxytetrahydrocorticosterone
• Pregnan-20-one, 3,21-dihydroxy-, (3α,5β)-
• Tetrahydro DOC
• Tetrahydro-11-deoxycorticosterone

Tetrahydrodeoxycorticosterone

CAS: 567-03-3

Tetrahydrodeoxycorticosterone

Fórmula: C₂₁H₃₄O₃

Pureza: 98%

Peso molecular: 334.49

Ref: 54-OR1137980

Tetrahydrodeoxycorticosterone

CAS: 567-03-3

Pureza: 98%

Ref: IN-DA00EBWF

5β-Pregnan-3α,21-diol-20-one-17α,21,21-d3

CAS: 567-03-3, 72205-58-4

Pureza: 97 atom % D

Forma y color: White Solid

Peso molecular: 337.52

Ref: 3U-D6461

Tetrahydrodeoxycorticosterone

CAS: 567-03-3

Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-induced currents at the GABAA receptor, and can be used in the study of neurological disorders.

Fórmula: C₂₁H₃₄O₃

Pureza: 99.40%

Forma y color: Solid

Peso molecular: 334.49

Ref: TM-T37725

Tetrahydrodeoxycorticosterone (Standard)

CAS: 567-03-3

Tetrahydrodeoxycorticosterone (Standard) is a reference standard for research and analysis in studies involving Tetrahydrodeoxycorticosterone. Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-induced currents at the GABAA receptor, and can be used in the study of neurological disorders.

Fórmula: C₂₁H₃₄O₃

Forma y color: Solid

Peso molecular: 334.49

Ref: TM-TMSM-3253

Tetrahydro 11-Deoxycorticosterone

Producto controlado

CAS: 567-03-3

Applications Tetrahydro 11-Deoxycorticosterone is a metabolite of 11-Deoxycorticosterone (DOC) (D232590).
References Fedele, E., et al.: J. Neurochem., 75, 782 (2000), Adkins, C., et al.: J. Biol. Chem., 276, 38934 (2001), Erceg, S., et al.: Brain Res., 1036, 115 (2005),

Fórmula: C₂₁H₃₄O₃

Forma y color: Neat

Peso molecular: 334.49

Ref: TR-T293270

Tetrahydro 11-deoxycorticosterone

Producto controlado

CAS: 567-03-3

Tetrahydro 11-deoxycorticosterone is a model system that is used to study the effects of steroids on the nervous system. It has been shown to bind to the α1 subunit of receptors and can also block cation channels. Tetrahydro 11-deoxycorticosterone may be useful in treating diseases such as Alzheimer's disease, epilepsy, and schizophrenia. This drug has also been shown to have a positive effect on body mass index in women.

Fórmula: C₂₁H₃₄O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 334.49 g/mol

Ref: 3D-FT28081

21-Hydroxypregnanolone

CAS: 567-03-3

Ref: BE-MU-2230

Tetrahydro 11-Deoxycorticosterone-D5

Producto controlado

CAS: 567-03-3

Fórmula: C₂₁D₅H₂₉O₃

Forma y color: Neat

Peso molecular: 339.524

Ref: TR-T293272