CAS 568565-11-7

L-Alanina, L-glutaminil-L-arginil-L-prolil-L-arginil-L-leucil-L-seril-L-histidil-L-lisilglicil-L-prolil-L-metionil-L-prolil-(9CI)

Descripción:

La sustancia química conocida como L-Alanina, L-glutaminil-L-arginil-L-prolina-L-arginil-L-leucina-L-serina-L-histidina-L-lisina-glicina-L-prolina-L-metionina-L-prolina, con el número CAS 568565-11-7, es un péptido sintético compuesto por múltiples aminoácidos. Este compuesto presenta una secuencia que incluye L-alanina, L-glutamina, L-arginina, L-prolina, L-leucina, L-serina, L-histidina, L-lisina y L-metionina, lo que indica su posible papel en procesos biológicos o aplicaciones en bioquímica. Los péptidos como este a menudo se estudian por sus propiedades estructurales y funcionales, ya que pueden influir en diversas funciones fisiológicas, incluidos los caminos de señalización y los procesos metabólicos. La presencia de múltiples aminoácidos sugiere que puede exhibir actividades biológicas específicas, actuando potencialmente como una molécula de señalización o influyendo en la síntesis de proteínas. Además, la estabilidad, solubilidad y reactividad del compuesto pueden variar según su composición y secuencia de aminoácidos, lo que lo convierte en un tema de interés en la investigación farmacéutica y bioquímica.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

InChI: InChI=1S/C63H107N23O16S/c1-34(2)28-42(81-52(92)39(13-7-22-72-62(67)68)78-58(98)47-17-11-26-86(47)59(99)40(14-8-23-73-63(69)70)79-50(90)37(65)18-19-48(66)88)53(93)83-44(32-87)55(95)82-43(29-36-30-71-33-75-36)54(94)77-38(12-5-6-21-64)51(91)74-31-49(89)84-24-9-15-45(84)57(97)80-41(20-27-103-4)60(100)85-25-10-16-46(85)56(96)76-35(3)61(101)102/h30,33-35,37-47,87H,5-29,31-32,64-65H2,1-4H3,(H2,66,88)(H,71,75)(H,74,91)(H,76,96)(H,77,94)(H,78,98)(H,79,90)(H,80,97)(H,81,92)(H,82,95)(H,83,93)(H,101,102)(H4,67,68,72)(H4,69,70,73)/t35-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1

Clave InChI: PZJZONZEQDOQAZ-COFPHXSQSA-N

SMILES: C[C@@H](C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCSC)NC(=O)[C@@H]2CCCN2C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC3=CN=CN3)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N

Sinónimos:

• Qrprlshkgpmpa
• [Ala13]-Apelin-13
• (Ala13)-Apelin-13 (Human, Bovine, Mouse, Rat)
• H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-Oh
• [Ala13]Apelin-13, human, bovine, mouse, rat (F13A) (2)
• [Ala13]Apelin 13 (human, mouse, rat, bovine)

(Ala¹³)-Apelin-13 (human, bovine, mouse, rat) (Salt form trifluoroacetate)

CAS: 568565-11-7

Specific anatagonist of apelin-13. Systemic administration of Apelin-13 F13A (30 µg/kg) abolished the blood pressure-lowering effects of apelin-13 (15 µg/kg) in hypertensive rats.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

Pureza: > 96%

Forma y color: White

Peso molecular: 1474.75

Ref: 01-4050032

(Ala¹³)-Apelin-13 (human, bovine, mouse, rat) (Salt form acetate)

CAS: 568565-11-7

(Ala13)-Apelin 13 showed scavenging abilities against active oxygen species such as superoxide and hydroxyl radicals. Apelin-13 F13A could act as an antioxidant that may have a therapeutic effect against diseases (e.g. arthritis and cancer) in which hydroxyl radical damage plays a role.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

Pureza: 100%

Forma y color: White

Peso molecular: 1474.75

Ref: 01-4095877

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

CAS: 568565-11-7

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

Pureza: ≥95%

Peso molecular: 1474.73

Ref: 54-OR1113288

(Ala13)-Apelin-13

CAS: 568565-11-7

(Ala13)-Apelin-13 is a useful organic compound for research related to life sciences. The catalog number is T35374 and the CAS number is 568565-11-7.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

Pureza: 98%

Forma y color: Solid

Peso molecular: 1474.75

Ref: TM-T35374

H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH

CAS: 568565-11-7

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S

Pureza: 95%

Peso molecular: 1474.7332

Ref: IN-DA00EA15

[Ala13]-Apelin-13 trifluoroacetate salt

CAS: 568565-11-7

Apelin-13 is a peptide that is involved in the regulation of locomotor activity and pain. It has been shown to decrease the activity of matrix metalloproteinases, growth factors, and collagen, which are all important for animal development. Apelin-13 also interacts with the factor receptor, which regulates platelet-derived growth. This peptide has been shown to have antinociceptive properties and can be used in a pain model. Apelin-13 also interacts with the cb2 receptor, which may regulate inflammation.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S·xC₂HF₃O₂

Pureza: Min. 95%

Ref: 3D-TXA56511

(Ala13)-Apelin-13 (human, bovine, mouse, rat) acetate salt

CAS: 568565-11-7

Apelin-13 is a peptide hormone that is secreted from the stomach and small intestine. It may have analgesic effects through its interaction with μ-opioid receptors, which are also activated by morphine. Apelin-13 has been shown to increase locomotor activity in rats, suggesting it can potentiate the antinociceptive effect of morphine.

Fórmula: C₆₃H₁₀₇N₂₃O₁₆S·xC₂H₄O₂

Pureza: Min. 95%

Peso molecular: 1,474.74 g/mol

Ref: 3D-FA110249