CAS 58-28-6

Clorhidrato de desipramina

Descripción:

Clorhidrato de desipramina es un antidepresivo tricíclico que se utiliza principalmente en el tratamiento del trastorno depresivo mayor y ciertos trastornos de ansiedad. Funciona inhibiendo la recaptación de norepinefrina y, en menor medida, de serotonina, aumentando así los niveles de estos neurotransmisores en la hendidura sináptica. Este mecanismo contribuye a sus efectos antidepresivos. La sustancia aparece como un polvo cristalino blanco a blanco amarillento y es soluble en agua, lo que la hace adecuada para la administración oral en forma de tabletas o como solución inyectable. Clorhidrato de desipramina tiene una vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Los efectos secundarios comunes pueden incluir boca seca, estreñimiento, retención urinaria y sedación, mientras que los riesgos más serios involucran problemas cardiovasculares y potencial de sobredosis. Debido a su perfil de efectos secundarios, generalmente se prescribe con precaución, particularmente en pacientes con condiciones cardíacas preexistentes. Como con todos los medicamentos, es esencial que los pacientes consulten a profesionales de la salud para obtener asesoramiento personalizado y monitoreo durante el tratamiento.

Fórmula: C₁₈H₂₃ClN₂

InChI: InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H

Clave InChI: InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N

SMILES: C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl

Sinónimos:

• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
• 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
• 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
• 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
• 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
• 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
• DMI hydrochloride
• Demethylimipramine hydrochloride
• Desimipramine, hydrochloride
• Desipramine HCl
• Desipramine hydrochloride [USAN:JAN]
• Desipramine monohydrochloride
• Desmethylimipramine chloride
• Desmethylimipramine hydrochloride
• Desmethylimipramine monohydrochloride
• Despramine Hydrochloride
• Ex 4355
• G 35020
• GMI
• Imipraminedemethyl hydrochloride
• Jb 8181
• N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
• N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
• Norpolake
• Norpramin
• Nortimil
• Nortrimil
• Nsc 114901
• Pertofran
• Pertofrane
• Pertofrin
• Petilil
• Petylyl
• Rmi 9,384A
• Unii-1Y58Do4My1
• Desipramine hydrochloride
• n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
• demethylimipraminehydrochloride
• Desipramine solution hydrochloride
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
• Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
• Desipramine hydrochloride solution
• desmethylimipraminehydrochloride
• dmihydrochloride
• 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
• imipraminedemethylhydrochloride
• g35020
• ex4355
• 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
• 3-(5,6-dihydrobenzo[b][1
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
• 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
• jb8181
• 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
• Desipramine Hydrochloride (125 mg)
• [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
• 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
• f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
• DESIPRAMINEHYDROCHLORIDE,USP
• DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION

Desipramine.HCl

CAS: 58-28-6

Forma y color: Neat

Ref: LP-DSP-1093-HC-10

Desipramine.HCl, 1mg/ml in Methanol (as free base)

CAS: 58-28-6

Forma y color: Single Solution

Ref: LP-DSP-1093-HC-1LM

Desipramine Hydrochloride

CAS: 58-28-6

Forma y color: Neat

Ref: 61-FOR0589.00

Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 58-28-6

Forma y color: Single Solution

Ref: 61-AMP0589.00-01

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Fórmula: C₁₈H₂₃ClN₂

Forma y color: Off-White

Peso molecular: 302.8416

Ref: 47-931

DESIPRAMINE HYDROCHLORIDE CRS

CAS: 58-28-6

DESIPRAMINE HYDROCHLORIDE CRS

Fórmula: C₁₈H₂₃ClN₂

Forma y color: Crystalline Powder. White. Powder.

Peso molecular: 302.8416

Ref: 41-D0500000

Desipramine Hydrochloride

CAS: 58-28-6

Antidepressants, tranquilizers and other psychotherapeutic agents, nesoi

Fórmula: C₁₈H₂₂N₂·HCl

Forma y color: White Off-White Powder

Peso molecular: 302.15498

Ref: 45-1172006

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.

Fórmula: C₁₈H₂₃ClN₂

Pureza: 99.58% - 99.94%

Forma y color: White To Off-White Powder

Peso molecular: 302.842

Ref: TM-T0991

Desipramine HCl

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Peso molecular: 266.39 36.46

Ref: 4Z-D-026

Desipramine hydrochloride

CAS: 58-28-6

Desipramine hydrochloride

Pureza: ≥98%

Peso molecular: 302.842g/mol

Ref: 54-BUP14958

Desipramine Hydrochloride

CAS: 58-28-6

Desipramine Hydrochloride

Pureza: 98%

Peso molecular: 302.84g/mol

Ref: 54-OR1027543

Desipramine hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Pureza: ≥ 97.0%

Forma y color: White to off-white powder

Peso molecular: 302.84

Ref: 7W-GP4485

Desipramine Hydrochloride

Producto controlado

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·ClH

Forma y color: Neat

Peso molecular: 302.84

Ref: 86-MM0589.00

Desipramine hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·ClH

Forma y color: Neat

Peso molecular: 302.84

Ref: 04-C12170167

Desipramine Hydrochloride

CAS: 58-28-6

Fórmula: C₁₈H₂₂N₂·HCl

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 302.85

Ref: 3B-D6181

Desipramine Hydrochloride

Producto controlado

CAS: 58-28-6

Applications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Fórmula: C₁₈H₂₂N₂·ClH

Forma y color: Off-White

Peso molecular: 302.84

Ref: TR-D290050

Desipramine HCl

Producto controlado

CAS: 58-28-6

Desipramine hydrochloride is a tricyclic antidepressant drug that has been used to treat depression. It is an ester of N-methyl-D-aspartate and inhibits the 5-HT2 receptors. Desipramine HCl has been shown to have anti-cancer properties in both animal models and human cell lines, inhibiting carcinoma cells’ growth. The drug also has an effect on locomotor activity in mice and its use may cause drug interactions with nonsteroidal anti-inflammatory drugs.

Fórmula: C₁₈H₂₃ClN₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 302.84 g/mol

Ref: 3D-FD21203