CAS 58-28-6
:Clorhidrato de desipramina
Descripción:
Clorhidrato de desipramina es un antidepresivo tricíclico que se utiliza principalmente en el tratamiento del trastorno depresivo mayor y ciertos trastornos de ansiedad. Funciona inhibiendo la recaptación de norepinefrina y, en menor medida, de serotonina, aumentando así los niveles de estos neurotransmisores en la hendidura sináptica. Este mecanismo contribuye a sus efectos antidepresivos. La sustancia aparece como un polvo cristalino blanco a blanco amarillento y es soluble en agua, lo que la hace adecuada para la administración oral en forma de tabletas o como solución inyectable. Clorhidrato de desipramina tiene una vida media relativamente larga, lo que permite una dosificación una vez al día en muchos casos. Los efectos secundarios comunes pueden incluir boca seca, estreñimiento, retención urinaria y sedación, mientras que los riesgos más serios involucran problemas cardiovasculares y potencial de sobredosis. Debido a su perfil de efectos secundarios, generalmente se prescribe con precaución, particularmente en pacientes con condiciones cardíacas preexistentes. Como con todos los medicamentos, es esencial que los pacientes consulten a profesionales de la salud para obtener asesoramiento personalizado y monitoreo durante el tratamiento.
Fórmula:C18H23ClN2
InChI:InChI=1/C18H22N2.ClH/c1-19-13-6-14-20-17-9-4-2-7-15(17)11-12-16-8-3-5-10-18(16)20;/h2-5,7-10,19H,6,11-14H2,1H3;1H
Clave InChI:InChIKey=XAEWZDYWZHIUCT-UHFFFAOYSA-N
SMILES:C(CCNC)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Sinónimos:- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine hydrochloride
- 10,11-Dihydro-5-(3-(methylamino)propyl)-5H-dibenz(b,f)azepine monohydrochloride
- 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine hydrochloride (1:1)
- 5-[3-(Methylamino)propyl]-5H-dibenz[b,f]azepine hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, hydrochloride
- 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-, monohydrochloride
- 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-, hydrochloride (1:1)
- DMI hydrochloride
- Demethylimipramine hydrochloride
- Desimipramine, hydrochloride
- Desipramine HCl
- Desipramine hydrochloride [USAN:JAN]
- Desipramine monohydrochloride
- Desmethylimipramine chloride
- Desmethylimipramine hydrochloride
- Desmethylimipramine monohydrochloride
- Despramine Hydrochloride
- Ex 4355
- G 35020
- GMI
- Imipraminedemethyl hydrochloride
- Jb 8181
- N-(gamma-Methylaminopropyl)iminodibenzyl hydrochloride
- N-(γ-Methylaminopropyl)iminodibenzyl hydrochloride
- Norpolake
- Norpramin
- Nortimil
- Nortrimil
- Nsc 114901
- Pertofran
- Pertofrane
- Pertofrin
- Petilil
- Petylyl
- Rmi 9,384A
- Unii-1Y58Do4My1
- Desipramine hydrochloride
- n-(gamma-methylaminopropyl)iminodibenzylhydrochloride
- demethylimipraminehydrochloride
- Desipramine solution hydrochloride
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(monohydrochlor
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine
- Desipramine Hydrochloride (125 mg)I0E2831.000mg/mg(dr)
- Desipramine hydrochloride solution
- desmethylimipraminehydrochloride
- dmihydrochloride
- 5H-Dibenzb,fazepine-5-propanamine, 10,11-dihydro-N-methyl-, monohydrochloride
- imipraminedemethylhydrochloride
- g35020
- ex4355
- 10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(b,f)azepinehydrochloride
- 3-(5,6-dihydrobenzo[b][1
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methyl-amine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine hydrochloride
- 10,11-Dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methyl-propan-1-amine hydrochloride
- jb8181
- 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
- Desipramine Hydrochloride (125 mg)
- [3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]methylamine hydrochloride
- 10,11-DIHYDRO-N-METHYL-5-H-DIBENZ-[B,F]AZEPINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-5-(3-(methylamino)propyl)-5h-dibenz(hydrochlorid
- DESIPRAMINEHYDROCHLORIDE,USP
- DESIPRAMINE HYDROCHLORIDE METHANOL*SOLUT ION
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Desipramine Hydrochloride
CAS:Fórmula:C18H22N2·HClPureza:>98.0%(HPLC)(T)Forma y color:White to Light yellow powder to crystalPeso molecular:302.85Desipramine hydrochloride
CAS:Desipramine hydrochlorideFórmula:C18H23ClN2Forma y color:Off-WhitePeso molecular:302.8416DESIPRAMINE HYDROCHLORIDE CRS
CAS:DESIPRAMINE HYDROCHLORIDE CRSFórmula:C18H23ClN2Forma y color:Added ModifiedPeso molecular:302.8416Desipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeutic agents, nesoiFórmula:C18H22N2·HClForma y color:White Off-White PowderPeso molecular:302.15498Desipramine hydrochloride
CAS:Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine.Fórmula:C18H23ClN2Pureza:99.58% - 99.96%Forma y color:Gray SolidPeso molecular:302.842Desipramine Hydrochloride
CAS:Desipramine HydrochlorideFórmula:C18H23ClN2Pureza:>98%Forma y color:SolidPeso molecular:302.84Desipramine hydrochloride
CAS:Fórmula:C18H22N2·HClPureza:≥ 97.0%Forma y color:White to off-white powderPeso molecular:302.84Desipramine hydrochloride
CAS:Desipramine hydrochlorideFórmula:C18H23ClN2Pureza:≥98%Forma y color:SolidPeso molecular:302.842Desipramine HCl (N-Desmethyl Imipramine HCl, N-Desmethyl Clomipramine HCl EP Impurity B HCl, Norimipramine HCl)
CAS:Fórmula:C18H22N2HClPeso molecular:266.39 36.46Desipramine.HCl, 1mg/ml in Methanol (as free base)
CAS:Fórmula:C18H22N2·ClHForma y color:ColourlessPeso molecular:302.84Desipramine Hydrochloride 1.0 mg/ml in Methanol (as free base)
CAS:Fórmula:C18H22N2·ClHForma y color:ColourlessPeso molecular:302.84Desipramine hydrochloride (Standard)
CAS:Desipramine hydrochloride (Standard) is a reference standard for research and analysis in studies involving Desipramine hydrochloride. Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-uptake of neurotransmitters, including norepinephrine and serotonin. This leads to an increase in the amount of these neurotransmitters in the synaptic cleft and prolongs their activities postsynaptically.Fórmula:C18H23ClN2Forma y color:SolidPeso molecular:302.842Desipramine Hydrochloride
CAS:Producto controladoFórmula:C18H22N2·ClHForma y color:NeatPeso molecular:302.84Desipramine Hydrochloride
CAS:Producto controladoApplications Tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),Fórmula:C18H22N2·ClHForma y color:NeatPeso molecular:302.84
