CAS 58546-54-6

Gomisina A

Descripción:

Gomisina A es un compuesto natural clasificado como un lignano, derivado principalmente del fruto de la planta Schisandra chinensis, conocido comúnmente por sus usos medicinales tradicionales. Se caracteriza por su compleja estructura policíclica, que contribuye a su actividad biológica. Gomisina A exhibe diversas propiedades farmacológicas, incluyendo efectos antioxidantes, antiinflamatorios y hepatoprotectores, lo que lo hace de interés tanto en la medicina tradicional como en la farmacología moderna. El compuesto ha sido estudiado por sus posibles efectos neuroprotectores y su capacidad para modular ciertas vías de señalización, lo que puede tener implicaciones para condiciones como las enfermedades neurodegenerativas. Además, Gomisina A ha mostrado promesas en la mejora de la función hepática y en la protección contra el daño hepático. Su solubilidad y estabilidad en diferentes disolventes pueden variar, influyendo en su biodisponibilidad y eficacia en aplicaciones terapéuticas. En general, Gomisina A representa un área significativa de investigación en la química de productos naturales y farmacología, destacando la importancia de los compuestos derivados de plantas en la gestión de la salud y la enfermedad.

Fórmula: C₂₃H₂₈O₇

InChI: InChI=1S/C23H28O7/c1-12-7-13-8-16-20(30-11-29-16)22(28-6)17(13)18-14(10-23(12,2)24)9-15(25-3)19(26-4)21(18)27-5/h8-9,12,24H,7,10-11H2,1-6H3

Clave InChI: InChIKey=ZWRRJEICIPUPHZ-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC(OC)=C(OC)C3OC)CC(C)(O)C(C)CC2=CC4=C1OCO4

Sinónimos:

• (6R,7R)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
• (6S,7S)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol
• (6S,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol
• 1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-6-Ol
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6S,7S,13aR)-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer
• Gomisin A
• Schisandrol B
• Schisantherinol B
• Tjn 101
• Wuweizi alcohol B
• Wuweizichun B
• benzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7R)-

Schizandrol B

CAS: 58546-54-6

Schizandrol B

Fórmula: C₂₃H₂₈O₇

Pureza: 99%

Peso molecular: 416.46

Ref: 54-OR1023901

Schisandrol B

CAS: 58546-54-6

Schisandrol B

Fórmula: C₂₃H₂₈O₇

Pureza: ≥98%

Peso molecular: 416.46

Ref: 54-BUP10550

Schisandrol B

CAS: 58546-54-6

Fórmula: C₂₃H₂₈O₇

Peso molecular: 416.46

Ref: 7W-GP1275

Schizandrol B

CAS: 58546-54-6

Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.

Fórmula: C₂₃H₂₈O₇

Pureza: 95%~99%

Peso molecular: 416.47

Ref: BP-BP1266

Schisandrol B (Standard)

CAS: 58546-54-6

Schisandrol B (Standard) is a reference standard for research and analysis in studies involving Schisandrol B. 1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.

Fórmula: C₂₃H₂₈O₇

Forma y color: Solid

Peso molecular: 416.46

Ref: TM-TMSM-2891

Gomisin A

CAS: 58546-54-6

Fórmula: C₂₃H₂₈O₇

Pureza: >96.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 416.47

Ref: 3B-G0537

Schisandrol B

CAS: 58546-54-6

Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.

Fórmula: C₂₃H₂₈O₇

Pureza: 99.14% - 99.95%

Forma y color: Solid

Peso molecular: 416.46

Ref: TM-T6S1917

Schisandrol B

CAS: 58546-54-6

Ether alcohol phenol

Fórmula: C₂₃H₂₈O₇

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 416.47

Ref: 5G-80206

Schizandrol B

Producto controlado

CAS: 58546-54-6

Schizandrol B is a natural compound that has been shown to protect against oxidative stress and decrease the mitochondrial membrane potential. Schizandrol B inhibits human cyp3a4, which is an enzyme that metabolizes drugs. The linear calibration curve was able to be obtained from the signal pathways in human cells. The analytical method used was matrix effect-free. Experimental models were used to show that schizandrol B has an inhibitory effect on locomotor activity and skin tumor formation. It also has been found to be a substrate for p-gp, which transports drugs across the cell membrane, and can therefore alter absorption of drugs, including gomisin A. Schizandrol B also modulates enzyme activities in vitro as well as in vivo.

Fórmula: C₂₃H₂₈O₇

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 416.46 g/mol

Ref: 3D-FS65449

Schizandrol B - Bio-X ™

Producto controlado

CAS: 58546-54-6

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₃H₂₈O₇

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 416.46 g/mol

Ref: 3D-BS300127

Schisandrol B

CAS: 58546-54-6

(6S,7S,13aR)-1,2,3,13-Tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-6-ol

Fórmula: C₂₃H₂₈O₇

Pureza: 99+%

Peso molecular: 416.46

Ref: IN-DG132361

Gomisin A

CAS: 58546-54-6

Fórmula: C₂₃H₂₈O₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 416.4642

Ref: IN-DA003U7V