CAS 5968-70-7

Ácido acetil-β-boswélico

Descripción:

Ácido acetil-β-boswélico es un compuesto triterpenoide pentacíclico derivado de la resina del árbol Boswellia serrata, conocido comúnmente por sus propiedades antiinflamatorias y analgésicas. Este compuesto se caracteriza por su estructura química única, que incluye un sistema de anillos fusionados que contribuye a su actividad biológica. Ácido acetil-β-boswélico exhibe una variedad de efectos farmacológicos, incluida la inhibición de mediadores proinflamatorios, lo que lo convierte en un interés en el tratamiento de condiciones como la artritis y otras enfermedades inflamatorias. Su mecanismo de acción implica la modulación de varias vías de señalización, incluida la inhibición de la síntesis de leucotrienos. Además, este compuesto ha mostrado potencial en la promoción de la apoptosis en células cancerosas y puede poseer propiedades neuroprotectoras. Debido a su origen natural, a menudo se considera una alternativa más segura a los medicamentos antiinflamatorios sintéticos. Sin embargo, se necesita más investigación para comprender completamente su eficacia, dosis óptimas y posibles efectos secundarios en aplicaciones clínicas.

Fórmula: C₃₂H₅₀O₄

InChI: InChI=1S/C32H50O4/c1-19-11-14-28(4)17-18-30(6)22(26(28)20(19)2)9-10-23-29(5)15-13-25(36-21(3)33)32(8,27(34)35)24(29)12-16-31(23,30)7/h9,19-20,23-26H,10-18H2,1-8H3,(H,34,35)/t19-,20+,23-,24-,25-,26+,28-,29-,30-,31-,32-/m1/s1

Clave InChI: InChIKey=YJBVHJIKNLBFDX-MQURJEHKSA-N

SMILES: C[C@]12[C@@]([C@]3(C)[C@@](CC1)([C@](C(O)=O)(C)[C@H](OC(C)=O)CC3)[H])(CC=C4[C@@]2(C)CC[C@]5(C)[C@]4([C@@H](C)[C@H](C)CC5)[H])[H]

Sinónimos:

• (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid
• (3Α)-3-(Acetyloxy)Urs-12-En-24-Oic Acid
• (3α)-3-Acetoxyurs-12-en-24-oic acid
• (3α,4β)-3-(Acetyloxy)urs-12-en-23-oic acid
• 3-O-Acetyl-β-boswellic acid
• 3α-Acetoxyurs-12-en-24-oic acid
• 3α-Acetyl-β-boswellic acid
• Acetyl-β-boswellic acid
• Beta-Boswellic Acid,3-Acetyl
• Urs-12-En-24-Oic Acid, 3-(Acetyloxy)-, (3Α)-
• Urs-12-en-23-oic acid, 3-(acetyloxy)-, (3α,4β)-
• Urs-12-en-24-oic acid, 3α-hydroxy-, acetate

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-β-boswellic acid

Fórmula: C₃₂H₅₀O₄

Pureza: ≥95%

Peso molecular: 498.74

Ref: 54-BUP02661

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Peso molecular: 498.74

Ref: 7W-GL8130

(3R,4R,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-3-Acetoxy-4,6a,6b,8a,11,12,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicene-4-carboxylic acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Pureza: 95%

Forma y color: Solid

Peso molecular: 498.7370

Ref: IN-DA003AJD

3-Acetyl-β-boswellic acid (Standard)

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid (Standard) is a reference standard for research and analysis in studies involving 3-Acetyl-beta-boswellic acid. 3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC₅₀ values ranging from 0.6 to 7.1 microM.

Fórmula: C₃₂H₅₀O₄

Peso molecular: 498.737

Ref: TM-TMSM-0187

3-O-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-O-Acetyl-beta-boswellic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₂H₅₀O₄

Pureza: (HPLC) ≥98%

Forma y color: Powder

Peso molecular: 498.75

Ref: 11-2314S

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Pureza: 95%~99%

Peso molecular: 498.748

Ref: BP-BPF0530

3-O-Acetyl-beta-boswellic Acid

CAS: 5968-70-7

Applications 3-O-Acetyl-beta-boswellic acid possesses anti-inflammatory potential on key inflammatory mediators, TNF-α and IL-6. Main bioactive components of frankincense which is a fragrant resin obtained from plants of the genus Boswellia, acts as a cytotoxic agents. It is also a non-competitive 5-lipoxygenase and topoisomerase I and IIa.
References Sharma, S., et al.: Bioorg. Med. Chem. Lett., 26, 695-698 (2016); Csuk, R., et al.: Tetrahedron, 71, 2025-2034 (2015); Csuk, R., et al.: Eur. J. Med. Chem., 100, 98-105 (2015);

Fórmula: C₃₂H₅₀O₄

Forma y color: Neat

Peso molecular: 498.74

Ref: TR-A177770

3-Acetyl-β-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner.

Fórmula: C₃₂H₅₀O₄

Pureza: 95.62% - 99.17%

Forma y color: Solid

Peso molecular: 498.737

Ref: TM-TN1258

3-O-Acetyl-β-boswellic Acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Peso molecular: 498.75

Ref: 4Z-B-134002

3-O-Acetyl β-boswellic acid

CAS: 5968-70-7

Carboxylic acid with alcohol function

Fórmula: C₃₂H₅₀O₄

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 498.75

Ref: 5G-89152

3-Acetyl-beta-boswellic acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Peso molecular: 498.7

Ref: BE-RMCB180002

Acetyl β-boswellic acid

CAS: 5968-70-7

Fórmula: C₃₂H₅₀O₄

Peso molecular: 498.7

Ref: BE-RMT17834

3-Acetyl-beta-boswellic acid

CAS: 5968-70-7

3-Acetyl-beta-boswellic acid is a pentacyclic triterpenoid compound, which is derived from the resin of the Boswellia serrata tree. It exhibits significant biological activity, mainly due to its anti-inflammatory properties. The mode of action primarily involves the inhibition of 5-lipoxygenase, an enzyme crucial in the biosynthesis of leukotrienes, which are mediators in inflammatory and allergic responses. Additionally, it has been shown to modulate various signaling pathways and transcription factors involved in inflammation.

Fórmula: C₃₂H₅₀O₄

Pureza: Min. 95%

Peso molecular: 498.74 g/mol

Ref: 3D-FA65590