CAS 599179-03-0

5-({4-[(3S)-4-{(1R)-2-metoxi-1-[4-(trifluorometil)fenil]etil}-3-metilpiperazin-1-il]-4-metilpiperidin-1-il}carbonil)-4,6-dimetilpirimidina (2Z)-but-2-enedioato

Descripción:

La sustancia química conocida como "5-({4-[(3S)-4-{(1R)-2-metoxi-1-[4-(trifluorometil)fenil]etil}-3-metilpiperazin-1-il]-4-metilpiperidin-1-il}carbonil)-4,6-dimetilpirimidina (2Z)-but-2-enedioato" con número CAS 599179-03-0 es un compuesto orgánico complejo caracterizado por su intrincada estructura molecular, que incluye múltiples grupos funcionales y centros quirales. Este compuesto presenta un núcleo de pirimidina, que está sustituido con varias moieties de piperidina y piperazina, contribuyendo a su posible actividad biológica. La presencia de un grupo metoxi y un grupo trifluorometilo indica una posible lipofilia y propiedades farmacológicas mejoradas. La moiety (2Z)-but-2-enedioato sugiere que puede participar en reacciones o interacciones químicas específicas, particularmente en sistemas biológicos. En general, este compuesto probablemente exhiba un interés significativo en la química medicinal, particularmente en el desarrollo de fármacos, debido a su complejidad estructural y posibles aplicaciones terapéuticas. Sin embargo, serían necesarios estudios detallados para elucidar completamente sus propiedades, incluyendo solubilidad, estabilidad y actividad biológica.

Fórmula: C₃₂H₄₂F₃N₅O₆

InChI: InChI=1/C28H38F3N5O2.C4H4O4/c1-19-16-35(14-15-36(19)24(17-38-5)22-6-8-23(9-7-22)28(29,30)31)27(4)10-12-34(13-11-27)26(37)25-20(2)32-18-33-21(25)3;5-3(6)1-2-4(7)8/h6-9,18-19,24H,10-17H2,1-5H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t19-,24-;/m0./s1

SMILES: C[C@H]1CN(CCN1[C@@H](COC)c1ccc(cc1)C(F)(F)F)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C.C(=C\C(=O)O)\C(=O)O

Sinónimos:

• (4,6-Dimethylpyrimidin-5-yl){4-[(3S)-4-{(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl}-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}methanone (2Z)-but-2-enedioate (1:1)
• methanone, (4,6-dimethyl-5-pyrimidinyl)[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-1-piperidinyl]-, (2Z)-2-butenedioate (1:1)
• Vicriviroc maleate
• 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate

Vicriviroc Maleate

CAS: 599179-03-0

Fórmula: C₃₂H₄₂F₃N₅O₆

Pureza: 98.37%

Forma y color: Solid

Peso molecular: 649.7010

Ref: IN-DA00E9C8

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate

Fórmula: C₃₂H₄₂F₃N₅O₆

Pureza: ≥95%

Peso molecular: 649.7

Ref: 54-BUP07393

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.

Fórmula: C₃₂H₄₂F₃N₅O₆

Pureza: 98.16% - 98.37%

Forma y color: White Solid

Peso molecular: 649.7

Ref: TM-T3435

Vicriviroc maleate

CAS: 599179-03-0

Vicriviroc maleate is an antiviral compound that exhibits potent activity against HIV-1. It acts by blocking the interaction between the viral envelope protein gp120 and the chemokine receptor CCR5, thereby inhibiting viral entry into target cells. Vicriviroc maleate has been shown to have high specificity for CCR5 and does not affect other chemokine receptors, such as CXCR4. This compound is available in the form of microcapsules, which provide sustained release of the active ingredient over time. The microcapsules are formulated with caffeine, phenol and/or tartaric acid, peptidoglycan, fatty acid, sevelamer, potassium borate, dopamine, and other excipients to enhance stability and bioavailability. Vicriviroc maleate is water-soluble and can be easily administered orally or intravenously. It has also been studied for its potential effects on potassium channels and chemokine-mediated signaling pathways

Fórmula: C₂₈H₃₈F₃N₅O₂•C₄H₄O₄

Pureza: Min. 95%

Peso molecular: 649.7 g/mol

Ref: 3D-ZYA17903