CAS 633-65-8

Clorhidrato de berberina

Descripción:

Clorhidrato de berberina es una sal de amonio cuaternario derivada del alcaloide berberina, que se encuentra en varias plantas, incluyendo la goldenseal y el agracejo. Se caracteriza por su color amarillo brillante y es conocida por su sabor amargo. La sustancia es soluble en agua y alcohol, lo que la hace adecuada para diversas formulaciones farmacéuticas. Clorhidrato de berberina exhibe una variedad de actividades biológicas, incluyendo propiedades antimicrobianas, antiinflamatorias y antidiabéticas, que han despertado interés tanto en la medicina tradicional como en la moderna. Su mecanismo de acción implica la modulación de varias vías celulares, incluidas las relacionadas con el metabolismo de la glucosa y la regulación de lípidos. Además, se ha estudiado la berberina por sus posibles efectos en la salud cardiovascular y la microbiota intestinal. Debido a sus diversos efectos farmacológicos, Clorhidrato de berberina se utiliza a menudo en suplementos dietéticos y remedios herbales, aunque su uso debe abordarse con precaución debido a posibles interacciones con otros medicamentos y efectos secundarios. En general, Clorhidrato de berberina es un compuesto de interés significativo tanto en contextos de investigación como terapéuticos.

Fórmula: C₂₀H₁₈ClNO₄

InChI: InChI=1/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;

Clave InChI: InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

SMILES: O(C)C1=C2C=[N+]3C(C=4C(=CC5=C(C4)OCO5)CC3)=CC2=CC=C1OC.[Cl-]

Sinónimos:

• 1,3-Benzodioxolo[5,6-A]Benzo[G]Quinolizinium, 5,6-Dihydro-9,10-Dimethoxy-, Hydrochloride (1:1)
• 16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
• Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
• Berberberberine hydrochloride n-hydrate
• Berberine IR
• Berberine chloride
• Berberine hcl
• Berberinium chloride
• Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
• NSC 163088
• NSC 646666
• ine HCl
• Berberine hydrochloride
• Berberine chloride form,Natural Yellow18
• 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
• Berberine chloride form
• Berberine chloride ,98%
• Kyoberin
• Berberine hydrochloride hydrate,97%
• Berberdine HCl
• BERBERINECHLORIDE(SH)
• 9,10-Dimethoxy-5,6-dihydro-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• BERBERINE CHLORIDE(AHP)
• 9,10-Dimethoxy-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium·chloride
• berberiniumchloride
• NATURAL YELLOW 18
• BERBERIN HCL
• UMBELLATINE
• TIMTEC-BB SBB006488
• LABOTEST-BB LT00440956
• C.I.Natural Yellow 18
• Berberine Chloride, JP
• 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
• BBR
• BERBERINE HYDROCHLORIDE N-HYDRATE
• 7,8,13,13a-Tetradehydro-9,10-diMethoxy-2,3-(Methylenedioxy)berbiniuM Chloride
• Berberin chloride dihydrate
• Berberinehydrochloride，Berberine chloride form
• 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
• 9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
• NATURAL YELLOW 18 CHLORIDE
• Berberine chloride (TN)
• CI 75160

Berberine chloride

CAS: 633-65-8

Berberine is an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme Cox-2 (cyclooxygenase-2) which is abundantly expressed in colon cancer cells. Also inhibits c-Jun (Activator Protein 1), a transcription factor that plays a critical r

Fórmula: C₂₀H₁₈ClNO₄

Forma y color: Yellow to orange, Powder

Peso molecular: 371.82

Ref: 02-J62311

BERBERINE CHLORIDE CRS

CAS: 633-65-8

BERBERINE CHLORIDE CRS

Fórmula: C₂₀H₁₉ClNO₄

Peso molecular: 372.8216

Ref: 41-Y0001149

Berberine chloride

CAS: 633-65-8

Berberine chloride

Fórmula: C₂₀H₁₈NO₄

Pureza: 77.7%

Forma y color: White

Peso molecular: 336.12358

Ref: 47-1108

Berberine chloride

CAS: 633-65-8

Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 99.47% - 99.93%

Forma y color: Yellow Crystalline Powder

Peso molecular: 371.80

Ref: TM-T0461

Berberine chloride

CAS: 633-65-8

Berberine chloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 99.5%

Forma y color: Solid

Peso molecular: 371.8

Ref: 54-BUP19732

Berberine hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 96.0 - 104.0 % (dried basis)

Forma y color: Yellow or orange powder

Peso molecular: 371.82

Ref: 7W-GK8292

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 0.98

Forma y color: Solid

Peso molecular: 371.81

Ref: 54-OR1028076

Berberine hydrochloride

CAS: 633-65-8

Berberine hydrochloride (berberine), a natural plant alkaloid derived from Chinese herbal medicine, is characterized by diverse pharmacological effects, such as anticancer and lower elevated blood glucose, it can prevent adhesion by downregulating ICAM-1 and reduce inflammation by inhibiting the TAK1/JNK and TAK1/NF-κB signaling after abdominal surgery, which brings out a good therapeutic approach for the development of clinical application for postoperative abdominal adhesion and inflammation.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 95%~99%

Forma y color: Powder

Peso molecular: 371.817

Ref: BP-BP0252

Berberine Chloride

Producto controlado

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄·Cl

Forma y color: Neat

Peso molecular: 371.81

Ref: 86-MM1632.00

Berberine chloride

CAS: 633-65-8

Berberine chloride analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₂₀H₁₈ClNO₄

Pureza: (HPLC) ≥95%

Forma y color: Powder

Peso molecular: 371.82

Ref: 11-0601

Berberine chloride

Producto controlado

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄·Cl

Forma y color: Neat

Peso molecular: 371.81

Ref: 04-C10573950

9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 371.8142

Ref: IN-DA00IB6S

Berberine chloride (Standard)

CAS: 633-65-8

Berberine chloride (Standard) is a reference standard for research and analysis in studies involving Berberine chloride. Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.

Fórmula: C₂₀H₁₈ClNO₄

Forma y color: Solid

Peso molecular: 371.80

Ref: TM-TMSM-2973

Berberine hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 371.82

Ref: 10-F516404

Berberine Chloride Hydrate

Producto controlado

CAS: 633-65-8

Stability Hygroscopic
Applications An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Fórmula: C₂₀H₁₈NO₄·Cl

Forma y color: Neat

Peso molecular: 371.81

Ref: TR-B318150

Berberine Hydrochloride-d6

Producto controlado

CAS: 633-65-8

Stability Hygroscopic
Applications Berberine Hydrochloride-d6 is labelled Berberine Hydrochloride (B318150), an isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells
References Zhang, X. et al.: Cancer Res., 70, 9895 (2010); Lin, H.L. et al.: Cancer 85, 1937(1999); Schumacher, M.A. et al.: Science, 294, 2158 (2001); Fukuda, K. et al.: J. Ethno., 66, 227(1999);

Fórmula: C₂₀H₁₂D₆ClNO₄

Forma y color: Neat

Peso molecular: 377.85

Ref: TR-B318152

Berberine Hydrochloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈ClNO₄

Peso molecular: 371.8

Ref: BE-RMT20800

Berberine chloride

CAS: 633-65-8

9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride

Fórmula: C₂₀H₁₈ClNO₄

Pureza: 97%

Peso molecular: 371.81

Ref: IN-DG21926

Berberine Chloride

CAS: 633-65-8

Fórmula: C₂₀H₁₈NO₄Cl

Peso molecular: 336.4 : 35.5

Ref: ST-EA-CP-B118001