CAS 644-37-1

Fórmula: C4H4N4O3

InChI: InChI=1S/C4H4N4O3/c9-3-2(7-8-11)1-5-4(10)6-3/h1H,(H,7,11)(H2,5,6,9,10)

Clave InChI: OIXPJPUFFXAGLN-UHFFFAOYSA-N

SMILES: C1=C(C(=O)NC(=O)N1)NN=O

NSC20116

CAS: 644-37-1

NSC20116 is a uracil derivative that specifically targets the Set-and-Ring (SRA) domain of the oncogene UHRF1. It binds to the 5-methylcytosine (5mC) recognition pocket within the UHRF1SRA domain, with a dissociation constant (Kd) of 362 nM. NSC20116 is applicable for cancer research.

Fórmula: C₄H₄N₄O₃

Peso molecular: 156.1

Ref: TM-T213072