CAS 6533-00-2
:Norgestrel
Descripción:
Norgestrel es un progestágeno sintético, utilizado principalmente en anticonceptivos hormonales y terapias de reemplazo hormonal. Se caracteriza por su capacidad para imitar la hormona natural progesterona, influyendo así en varios procesos fisiológicos. Norgestrel es conocido por su efectividad en la prevención de la ovulación, alterando el ciclo menstrual y proporcionando protección endometrial. El compuesto se administra típicamente en forma oral, a menudo en combinación con estrógeno en píldoras anticonceptivas. Químicamente, Norgestrel es un derivado de la testosterona, con una estructura esteroidea modificada que mejora su actividad progestacional mientras minimiza los efectos androgénicos. Es lipofílico, lo que permite una buena absorción y distribución en el cuerpo. La sustancia se metaboliza en el hígado, y su farmacocinética puede verse influenciada por factores como la edad, el peso y los medicamentos concurrentes. Al igual que con cualquier tratamiento hormonal, los efectos secundarios potenciales pueden incluir cambios en el estado de ánimo, fluctuaciones de peso y alteraciones en los patrones menstruales. En general, Norgestrel desempeña un papel significativo en la salud reproductiva, proporcionando opciones efectivas para la anticoncepción y la regulación menstrual.
Fórmula:C21H28O2
InChI:InChI=1/C21H28O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23H,3,5-12H2,1H3/t16-,17+,18+,19-,20-,21-/s2
Clave InChI:InChIKey=WWYNJERNGUHSAO-PYYZKRFANA-N
SMILES:C(C)[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]
Sinónimos:- (.+-.)-13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
- (.+-.)-17α-Ethynyl-13-ethyl-17-hydroxygon-4-en-3-one
- (.+-.)-17α-Ethynyl-13β-ethylgon-4-en-17β-ol-3-one
- (.+-.)-Norgestrel
- (17α)-(±)-13-Ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one
- 13-Ethyl-17α-ethynyl-17β-hydroxy-4-gonen-3-one
- 18,19-Dinor-17α-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (.+-.)-
- <span class="text-smallcaps">DL</span>-Norgestrel
- DL-Norgestrel
- Fh 122A
- Methylnorethindrone
- Monovar
- Neogest
- Ovrette
- Postinor
- Sh 70850
- Sh 850
- Wy 3707
- dl-11β-Ethyl-17α-ethynyl-17β-hydroxygon-4-en-3-one
- dl-13-β-Ethyl-17-α-ethynyl-17-β-hydroxygon-4-en-3-one
- α-Norgestrel
- 13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- Norgestrel [USAN:INN:BAN:JAN]
- 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-,(17alpha)-(+-)-
- Norgestrel (DL-)
- (8R,9S,10R,13S,14S)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one
- dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone
- 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-
- 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-(±)-
- (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (non-preferred name)
- dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one
- Ver más sinónimos
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95
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Se han encontrado 20 productos.
NORGESTREL CRS
CAS:NORGESTREL CRSFórmula:C21H28O2Forma y color:Crystalline Powder. White. Powder.Peso molecular:312.4458Norgestrel
CAS:Estrogens and progestinsFórmula:C21H28O2Forma y color:White Off-White Crystalline PowderPeso molecular:312.20893(±)-13-Ethyl-17α-ethynyl-17-hydroxygon-4-en-3-one
CAS:Fórmula:C21H28O2Pureza:99%Forma y color:SolidPeso molecular:312.4458Norgestrel
CAS:Producto controladoFórmula:C21H28O2Forma y color:White To Off-WhitePeso molecular:312.45Norgestrel
CAS:Norgestrel (WY-3707), a synthetic progestin, is used for contraception and hinders LH/FSH, thickens mucus, and slows ova transit.Fórmula:C21H28O2Pureza:99.71% - 99.72%Forma y color:Crystals From Methanol White Crystalline PowderPeso molecular:312.45Norgestrel-d6 (Major)
CAS:Producto controladoApplications Labelled Norgestrel. It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.
References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),Fórmula:C21H22D6O2Forma y color:NeatPeso molecular:318.49Norgestrel
CAS:Producto controladoApplications Norgestrel is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.
References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),Fórmula:C21H28O2Forma y color:NeatPeso molecular:312.45Norgestrel
CAS:Producto controladoNorgestrel is a synthetic progestin that is used in hormonal contraceptives. It is also used to treat endometriosis, uterine bleeding, and other conditions. Norgestrel has been found to bind to the progesterone receptor and inhibit the secretion of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and thyroid-stimulating hormone (TSH). This drug also inhibits hepatic lipase activity and may reduce body mass index by increasing lipid metabolism. Basic fibroblasts incubated with nomegestrol acetate show an increased production of leukemia inhibitory factor (LIF) and neurotrophic factors that are important for cell growth and differentiation. These effects have not been seen in women using this drug for contraception, but have been observed in untreated groups of women.br> Norgestrel is a steroidal progestin which has been shown to increase the number of leukocytes in the uterus, particularlyFórmula:C21H28O2Pureza:Min. 95%Peso molecular:312.45 g/mol
