CAS 654655-80-8

Fórmula: C32H31BrN2O2

InChI: InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3

Clave InChI: QUIJNHUBAXPXFS-UHFFFAOYSA-N

SMILES: CN(C)CCC(C1=CC=CC2=CC=CC=C21)(C(C3=CC=CC=C3)C4=C(N=C5C=CC(=CC5=C4)Br)OC)O

(Rac)-Bedaquiline

CAS: 654655-80-8

Ref: IN-DA00EEJO

(Rac)-Bedaquiline

CAS: 654655-80-8

(Rac)-Bedaquiline

Fórmula: C₃₂H₃₁BrN₂O₂

Pureza: ≥95%

Peso molecular: 555.5

Ref: 54-OR1131922

rac-Bedaquiline (Mixture of Diastereomers)

CAS: 654655-80-8

Fórmula: C₃₂H₃₁BrN₂O₂

Peso molecular: 555.52

Ref: 4Z-B-101030

(Rac)-Bedaquiline

CAS: 654655-80-8

(Rac)-Bedaquiline is the racemic form of Bedaquiline. Bedaquiline (TMC207) acts as a diarylquinoline agent that targets the c- and ε-subunits to inhibit Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase. It possesses uncoupler activity and is employed in the treatment of multidrug-resistant tuberculosis.

Fórmula: C₃₂H₃₁BrN₂O₂

Peso molecular: 555.51

Ref: TM-TYD-04739

Bedaquiline (Mixture of Diastereomers)

CAS: 654655-80-8

Applications Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Fórmula: C₃₂H₃₁BrN₂O₂

Forma y color: Neat

Peso molecular: 555.5

Ref: TR-B119550

Bedaquiline-d6 (Mixture of Diastereomers)

Producto controlado

CAS: 654655-80-8

Applications Bedaquiline-d6 is the labelled analog of Bedaquiline, a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Fórmula: C₃₂₂H₆H₂₅BrN₂O₂

Forma y color: Neat

Peso molecular: 561.54

Ref: TR-B119552

Bedaquiline

CAS: 654655-80-8

Bedaquiline is a medicinal compound that acts as an inhibitor of protein kinases. It has been used as an anticancer agent due to its ability to inhibit the growth and proliferation of cancer cells. Bedaquiline works by binding to the ATP-binding site of kinases, thereby inhibiting their activity and leading to apoptosis in cancer cells. This compound has shown promise in treating Chinese hamster ovary (CHO) cells, which are commonly used in research for cancer therapies. Additionally, Bedaquiline has been found to be effective against urinary tract infections caused by certain bacteria by targeting the bacterial ATP synthase enzyme. This analog is a potent inhibitor of tumor growth and may have potential for the treatment of various types of cancers.

Fórmula: C₃₂H₃₁BrN₂O₂

Pureza: Min. 95%

Peso molecular: 555.5 g/mol

Ref: 3D-EBB65580

Rac-Bedaquiline

CAS: 654655-80-8

Fórmula: C₃₂H₃₁BrN₂O₂

Peso molecular: 555.5

Ref: ST-EA-CP-B50007