CAS 66-76-2
:Dicumarol
Descripción:
Dicumarol es un compuesto químico que pertenece a la clase de los anticoagulantes, específicamente un derivado de la cumarina. Se caracteriza por su capacidad para inhibir la epóxido reductasa de vitamina K, que es crucial para la síntesis de ciertos factores de coagulación en el hígado. Esta inhibición conduce a una disminución en los niveles de vitamina K activa, reduciendo así la coagulación sanguínea. Dicumarol aparece como un polvo cristalino blanco a amarillo pálido y es poco soluble en agua, pero más soluble en disolventes orgánicos como el etanol y la acetona. Su fórmula molecular es C18H12O5 y tiene un peso molecular relativamente bajo. El compuesto se utiliza principalmente en investigación y tiene una importancia histórica como uno de los primeros anticoagulantes orales. Debido a sus propiedades anticoagulantes, Dicumarol debe usarse con precaución, ya que puede provocar complicaciones hemorrágicas si no se monitorea adecuadamente. Además, se ha estudiado por sus posibles efectos en varios procesos biológicos, incluyendo su papel en la investigación del cáncer y como un posible agente terapéutico.
Fórmula:C19H12O6
InChI:InChI=1/C19H12O6/c20-16-10-5-1-3-7-14(10)24-18(22)12(16)9-13-17(21)11-6-2-4-8-15(11)25-19(13)23/h1-8,20-21H,9H2
Clave InChI:InChIKey=DOBMPNYZJYQDGZ-UHFFFAOYSA-N
SMILES:OC=1C=2C(OC(=O)C1CC3=C(O)C=4C(OC3=O)=CC=CC4)=CC=CC2
Sinónimos:- 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-
- 3,3'-Methylenebis[4-hydroxy-1,2-benzopyrone]
- 3,3'-Methylenebis[4-hydroxycoumarin]
- 3,3′-Methylene-bis-(4-hydroxy-2H-benzopyran-2-one)
- 3,3′-Methylenebis(4-hydroxy-2H-chromen-2-one)
- 3,3′-Methylenebis[4-hydroxy-2H-1-benzopyran-2-one]
- Acadyl
- Acavyl
- Antitrombosin
- Baracoumin
- Bis(4-hydroxycoumarin-3-yl)methane
- Bis-3,3'-(4-hydroxycoumarinyl)methane
- Bishydroxycoumarin
- Coumarin, 3,3'-methylenebis[4-hydroxy-
- Cuma
- Cumid
- Di-4-hydroxy-3,3'-methylenedicoumarin
- Dicoumal
- Dicoumarin
- Dicoumarol
- Dicuman
- Dicumarine
- Dicumol
- Dufalone
- Kumoran
- Melitoxin
- Nc 034
- Nsc 17860
- Nsc 221570
- Nsc 41834
- Pb 2-9
- Temparin
- Trombosan
- 3,3'-Methylen-bis(4-hydroxy-cumarin)
- syringidin
- dicoumarol 4,4'-dihydroxy-3,3'-methylenebis(2H-chromen-2-one)
- 3,3’-methylenebis(4-hydroxy-2h-1-benzopyran-2-on
- 3,3’-methylene-bis(4-hydroxycoumarine)
- 3,3μ-Methylenebis(4-hydroxycoumarin), Dicumarol
- DICUMAROL
- Dicumarol,99%
- 4,4’-dihydroxy-3,3’-methylenebiscoumarin
- 3,3’-metilen-bis(4-idrossi-cumarina)
- BIS-HYDROXYCOUMARIN
- 3,3’-methylenebis(4-hydroxy-coumari
- Dikumarol
- 3,3’-methylene-bis(4-hydroxycoumarine)(french)
- nc034
- 3,3'-Methylenebis
- 3,3'-Metilen-bis(4-idrossi-cumarina)
- Dicumarol (200 mg)
- Dicoumarin (=dicoumarol)
- METHYLENEBISHYDROXYCOUMARIN
- Dicumaol R
- Di-(4-hydroxy-3-coumarinyl)methane
- 3,3'-Methylene-bis(4-hydroxycoumarine)
- 3,3’-methyleen-bis(4-hydroxy-cumarine)
- 4-HYDROXY-3-[(4-HYDROXY-2-OXO-CHROMEN-3-YL)METHYL]CHROMEN-2-ONE
- dwukumarol
- BISCUMAROL
- 3,3’-methylen-bis(4-hydroxy-cumarin)
- dicumaolr
- 3,3'-Methyleen-bis(4-hydroxy-cumarine)
- 3,3’-methylenebis[4-hydroxy-2h-1-benzopyran-2-on
- Ver más sinónimos
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Pureza (%)
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100
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50
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90
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95
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100
Se han encontrado 13 productos.
Dicoumarol
CAS:Fórmula:C19H12O6Pureza:>98.0%(HPLC)(T)Forma y color:White to Almost white powder to crystalPeso molecular:336.30Dicumarol
CAS:Vitamin K reductase inhibitor possessing anticoagulant propertiesFórmula:C19H12O6Forma y color:White to off white, PowderPeso molecular:336.30Dicoumarol
CAS:Dicoumarol: an anticoagulant from moldy sweet-clover, depletes vitamin K, inhibits clotting enzymes.Fórmula:C19H12O6Pureza:98.11% - 99.9%Forma y color:White SolidPeso molecular:336.3Dicumarol-d8
CAS:Producto controladoApplications Isotope labelled Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of coumarin (C755380).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sail, V., et al.: Chem. Biol. Drug. Design., 81, 334 (2013); Zsila, F., et al.: Molec. Pharma., 10, 1668 (2013); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);Fórmula:C19D8H4O6Forma y color:NeatPeso molecular:344.34Dicoumarol
CAS:Dicumarol is a coumarin derivative that inhibits the activity of polymerase chain reaction (PCR) by binding to DNA. It is also an inhibitor of nitrate reductase, which is an enzyme that catalyzes the conversion of nitrate to nitrite. Dicumarol binds to the response element on DNA and blocks the transcription of genes. This drug also has been shown to inhibit squamous cell carcinoma cells through interaction with DNA and protein thiols.Fórmula:C19H12O6Pureza:Min. 95%Peso molecular:336.30 g/molDicumarol
CAS:Producto controladoApplications Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of Coumarin (C755380).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sail, V., et al.: Chem. Biol. Drug. Design., 81, 334 (2013); Zsila, F., et al.: Molec. Pharma., 10, 1668 (2013); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);Fórmula:C19H12O6Forma y color:NeatPeso molecular:336.34-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one
CAS:Fórmula:C19H12O6Pureza:98.0%Forma y color:SolidPeso molecular:336.299
![4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one](https://static.cymitquimica.com/products/10/thumb/F358134.jpg)
