CAS 68767-14-6

Loxoprofeno

Descripción:

Loxoprofeno es un fármaco antiinflamatorio no esteroideo (AINE) que se utiliza principalmente por sus propiedades analgésicas y antiinflamatorias. Se emplea comúnmente en el tratamiento del dolor y la inflamación asociados con condiciones como la artritis, el dolor muscular y el malestar postoperatorio. Loxoprofeno actúa inhibiendo las enzimas ciclooxigenasas (COX), que desempeñan un papel crucial en la síntesis de prostaglandinas, compuestos que median la inflamación y el dolor. La sustancia se caracteriza por su inicio de acción relativamente rápido y a menudo se formula en varias formas de dosificación, incluidas tabletas y aplicaciones tópicas. Loxoprofeno es conocido por su perfil de seguridad gastrointestinal favorable en comparación con otros AINE, lo que lo convierte en una opción preferida en ciertos escenarios clínicos. Sin embargo, como todos los medicamentos, puede tener efectos secundarios, incluidos trastornos gastrointestinales, riesgos cardiovasculares y posibles interacciones con otros fármacos. Su estructura química incluye un derivado del ácido propiónico, lo que contribuye a su actividad farmacológica. Al igual que con cualquier medicamento, es esencial usar Loxoprofeno bajo supervisión médica para garantizar la seguridad y la eficacia.

Fórmula: C₁₅H₁₈O₃

InChI: InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)

Clave InChI: InChIKey=YMBXTVYHTMGZDW-UHFFFAOYSA-N

SMILES: C(C1=CC=C(C(C(O)=O)C)C=C1)C2C(=O)CCC2

Sinónimos:

• 2-[4-(2-Oxo-Cyclopentylmethyl)-Phenyl]-Propionic Acid
• 2-[4-[(2-Oxocyclopentan-1-Yl)Methyl]Phenyl]Propionic Acid
• 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic acid
• 2-{4-[(2-Oxocyclopentyl)Methyl]Phenyl}Propanoic Acid
• A-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Alpha-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid
• Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
• Ioxoprofen
• Koloxo
• Loxoprofen Acid
• ��-Methyl-4-[(2-Oxocyclopentyl)Methyl]Benzeneacetic Acid

Loxoprofen

CAS: 68767-14-6

2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid

Fórmula: C₁₅H₁₈O₃

Pureza: 97%

Peso molecular: 246.3

Ref: IN-DG136713

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: >97.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 246.31

Ref: 3B-L0244

Loxoprofen

CAS: 68767-14-6

Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.

Fórmula: C₁₅H₁₈O₃

Pureza: 98.59%

Forma y color: White Solid

Peso molecular: 246.3

Ref: TM-T0463

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: 97%

Forma y color: Solid

Peso molecular: 246.3016

Ref: IN-DA003RD6

Loxoprofen-d4

CAS: 68767-14-6

Fórmula: C₁₅H₁₄D₄O₃

Forma y color: White To Off-White Solid

Peso molecular: 250.33

Ref: 4Z-L-8921

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Fórmula: C₁₅H₁₈O₃

Pureza: >98%

Peso molecular: 246.3

Ref: 54-OR1030277

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Forma y color: Off-White Solid

Peso molecular: 246.31

Ref: 4Z-L-891

Loxoprofen Impurity 1 and Loxoprofen Impurity 50

CAS: 68767-14-6

Fórmula: C₁₈H₂₄O₅

Peso molecular: 320.39

Ref: 4Z-L-8978

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: ≥ 97.0%

Forma y color: White to faint yellow crystalline powder

Peso molecular: 246.30

Ref: 7W-GP1810

Loxoprofen

CAS: 68767-14-6

Loxoprofen

Fórmula: C₁₅H₁₈O₃

Pureza: ≥98%, 10 mM in DMSO

Peso molecular: 246.3

Ref: 54-BUP15038

Loxoprofen-d6

CAS: 68767-14-6

Fórmula: C₁₅H₁₂D₆O₃

Peso molecular: 252.35

Ref: 4Z-L-897

Loxoprofen

Producto controlado

CAS: 68767-14-6

Applications Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Fórmula: C₁₅H₁₈O₃

Forma y color: Neat

Peso molecular: 246.3

Ref: TR-L472905

Loxoprofen-d3

Producto controlado

CAS: 68767-14-6

Applications Loxoprofen-d3, is the labeled analogue of Loxoprofen (L472905), which is non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation.
References Masahide H. et al.: J Clin Biochem Nutr., 47, 138 (2010); Noguchi, M. et al.: Biolog. Pharmac. Bull., 28, 2075 (2005); Hyun, J. et al.: Arch. Pharm. Res., 24, 541 (2001);

Fórmula: C₁₅H₁₅D₃O₃

Forma y color: Neat

Peso molecular: 249.32

Ref: TR-L472907

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a nonsteroidal anti-inflammatory drug that belongs to the group of drugs called NSAIDs. It has potent inhibitory activity against growth factor, which is important for the promotion of inflammation and tissue damage in diseases such as rheumatoid arthritis. Loxoprofen has been shown to have strong inhibitory effects on bacterial translocation in mice with colitis, which may be related to its ability to decrease the expression of endogenous substances through inhibition of colony-stimulating factor. Loxoprofen also has a high solubility in water (2g/L) and is soluble in biocompatible polymers such as polyvinylpyrrolidone.

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 246.31 g/mol

Ref: 3D-FL172231

Loxoprofen (low-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a non-steroidal anti-inflammatory drug that belongs to the class of drugs called pyrazoles. It is used in the treatment of inflammation and pain caused by arthritis, osteoarthritis, gout, menstrual pain, and dental pain. Loxoprofen binds to cyclooxygenase (COX) enzymes, thereby inhibiting prostaglandin synthesis. The COX enzymes are necessary for the production of prostaglandins that lead to inflammation and pain. Loxoprofen also inhibits bacterial translocation by binding to bacterial lipopolysaccharides on the cell surface and preventing their interaction with immune cells. Loxoprofen has been shown to inhibit colony stimulating factor (CSF) activity in vitro assays by disrupting CSF-1 binding to its receptor erythropoietin receptor or CD11b/CD18 integrin receptors on monocytes or neutrophils. This means that it will not stimulate the

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 246.3 g/mol

Ref: 3D-FL172228

Loxoprofen (high-melting polymorph)

CAS: 68767-14-6

Loxoprofen is a high-melting polymorph of loxoprofen, which is a nonsteroidal anti-inflammatory drug. Loxoprofen is used for the relief of pain and inflammation in patients with rheumatoid arthritis and osteoarthritis. It has been shown to be useful as an intermediate in the synthesis of other compounds, such as pharmaceuticals, pesticides, and dyes. Loxoprofen has also been found to be a useful building block in organic synthesis reactions that require high quality reagents.

Fórmula: C₁₅H₁₈O₃

Pureza: Min. 98.5 Area-%

Peso molecular: 246.31 g/mol

Ref: 3D-Q-201324

2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Pureza: 95%

Forma y color: Solid

Peso molecular: 246.306

Ref: 10-F093438

Loxoprofen

CAS: 68767-14-6

Fórmula: C₁₅H₁₈O₃

Peso molecular: 246.3

Ref: ST-EA-CP-L133000

Loxoprofen Sodium Salt Dihydrate

CAS: 226721-96-6, 68767-14-6, 80382-23-6

Fórmula: C₁₅H₁₇NaO₃·2H₂O

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 304.32

Ref: 3B-L0252

Loxoprofen RS

CAS: 68767-14-6

Forma y color: White Solid Crystalline Powder

Ref: 2K-1188000021