CAS 71989-18-9

N-(9-Fluorenilmetoxicarbonil)-L-ácido glutámico γ-terc-butil éster

Descripción:

N-(9-Fluorenilmetoxicarbonil)-L-ácido glutámico γ-terc-butil éster, comúnmente conocido como Fmoc-L-Glu(γ-tBu)-OH, es una forma protegida del aminoácido L-ácido glutámico. Este compuesto se caracteriza por la presencia de un grupo 9-fluorenilmetoxicarbonilo (Fmoc), que sirve como grupo protector para la funcionalidad amino, permitiendo reacciones selectivas durante la síntesis de péptidos. El grupo éster γ-tert-butilo proporciona protección adicional para la parte ácida carboxílica, mejorando la estabilidad y solubilidad del compuesto en disolventes orgánicos. Fmoc-L-Glu(γ-tBu)-OH se utiliza típicamente en la síntesis de péptidos en fase sólida, donde facilita el ensamblaje paso a paso de péptidos mientras previene reacciones secundarias no deseadas. El compuesto es generalmente estable bajo condiciones de laboratorio estándar, pero puede requerir condiciones específicas para la desprotección. Su estructura contribuye a su utilidad en bioquímica y química medicinal, particularmente en la síntesis de péptidos con propiedades funcionales específicas.

Fórmula: C₂₄H₂₇NO₆

InChI: InChI=1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m0/s1

Clave InChI: InChIKey=OTKXCALUHMPIGM-FQEVSTJZSA-N

SMILES: C(OC(N[C@@H](CCC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
• (2S)-5-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-5-oxopentanoic acid
• (2S)-5-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid
• (2S)-5-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• (4S)-5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• 5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
• FMOC-Glu(OtBu)-OH
• Fmoc-L-glutamic acid 5-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-glutamic acid γ-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)glutamic acid γ-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
• L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester

N-Fmoc-L-glutamic acid 5-tert-butyl ester, 98%

CAS: 71989-18-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₄H₂₇NO₆

Pureza: 98%

Peso molecular: 425.48

Ref: 02-H59169

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fórmula: C₂₄H₂₇NO₆

Pureza: 98%

Forma y color: Solid

Peso molecular: 425.4743

Ref: IN-DA0038GY

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fórmula: C₂₄H₂₇NO₆

Pureza: ≥ 99.0%

Forma y color: White powder

Peso molecular: 425.48

Ref: 7W-GM7333

Fmoc-L-glutamic acid 5-tert-butyl ester

CAS: 71989-18-9

Fmoc-L-glutamic acid 5-tert-butyl ester

Pureza: ≥98%

Peso molecular: 425.47g/mol

Ref: 54-BUP19524

5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate

CAS: 71989-18-9

Fórmula: C₂₄H₂₇NO₆

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 425.48

Ref: 3B-B3167

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

M03409 - Fmoc-Glu(OtBu)-OH

Fórmula: C₂₄H₂₇NO₆

Pureza: 99%

Forma y color: Powder or Crystalline Powder or Solid

Peso molecular: 425.481

Ref: 10-M03409

Fmoc-L-glutamic acid 5-tert-butyl ester

CAS: 71989-18-9

Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.

Fórmula: C₂₄H₂₇NO₆

Pureza: 99.68%

Forma y color: Solid

Peso molecular: 425.47

Ref: TM-T64329

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fmoc-Glu(OtBu)-OH

Fórmula: C₂₄H₂₇NO₆

Pureza: 98%

Forma y color: white powder

Peso molecular: 425.47g/mol

Ref: 54-OR911397

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fmoc-Glu(OtBu)-OH is an amino acid that is used in the synthesis of peptides and proteins. It is a hydrophilic, non-polar amino acid with a hydroxyl group at its carboxy terminus. This substance has been shown to inhibit the growth of cancer cells in vitro and has been used for the development of monoclonal antibodies. Fmoc-Glu(OtBu)-OH has also been shown to have pharmacokinetic properties that are different from other amino acids such as L-lysine, which may be due to its hydrophilic interactions with plasma proteins. This compound is also toxic, as shown by studies on rats where it was found to cause liver damage at high doses. Fmoc-Glu(OtBu)-OH binds to receptors on cells known as polysialic acid receptors, which are involved in cell adhesion and migration. Fmoc-Glu

Fórmula: C₂₄H₂₇NO₆

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 425.47 g/mol

Ref: 3D-FF28968

FMOC-L-Glutamic Acid 5-Tert-Butyl Ester (FMOC-Glu(OtBu)-OH) extrapure, 99%

CAS: 71989-18-9

Fórmula: C₂₄H₂₇NO₆

Pureza: min. 99%

Forma y color: White to off-white, Crystalline powder

Peso molecular: 425.47

Ref: SR-90673

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fórmula: C₂₄H₂₇NO₆

Peso molecular: 425.5

Ref: ST-EA-CP-L28030