
CAS 724440-27-1
:Fórmula:C20H14ClNO5S
InChI:InChI=1S/C20H14ClNO5S/c21-17-11-10-14(28(26,27)13-6-2-1-3-7-13)12-16(17)19(23)22-18-9-5-4-8-15(18)20(24)25/h1-12H,(H,22,23)(H,24,25)
Clave InChI:CLAUJSRBKSRTGQ-UHFFFAOYSA-N
SMILES:C1=CC=C(C=C1)S(=O)(=O)C2=CC(=C(C=C2)Cl)C(=O)NC3=CC=CC=C3C(=O)O
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BAY-8002
CAS:2-(2-Chloro-5-(phenylsulfonyl)benzamido)benzoic acidFórmula:C20H14ClNO5SPureza:98%Peso molecular:415.85BAY-8002
CAS:BAY-8002 is a potent dual MCT1/2 inhibitor (IC50 values are 3, 8, and 12 nM at rat (C6), human (DLD-1) and mouse (4T1) MCT1 respectively).Fórmula:C20H14ClNO5SPureza:98.7% - 99.13%Forma y color:SolidPeso molecular:415.847BAY 8002
CAS:Inhibitor of lactate uptake and efflux via monocarboxylate transporter MCT1. The blockade of lactate transport with BAY 8002 leads to accumulation of lactate and pyruvate in cells. The MCT1 inhibition decreased tumour growth most effectively in diffuse large B-cell lymphoma cell lines and in subsets of solid tumour models.
Fórmula:C20H14ClNO5SPureza:Min. 95%Forma y color:SolidPeso molecular:415.85 g/mol






