CAS 747-36-4

Sulfato de hidroxicloroquina

Descripción:

Sulfato de hidroxicloroquina es un medicamento antipalúdico e inmunomodulador que se utiliza principalmente para tratar la malaria, la artritis reumatoide y el lupus eritematoso. Es un derivado de la cloroquina y funciona interfiriendo con el crecimiento de parásitos en los glóbulos rojos. El compuesto se caracteriza por su capacidad para inhibir la actividad lisosomal dentro de las células, lo cual es crucial para la supervivencia de ciertos patógenos. Sulfato de hidroxicloroquina se administra típicamente en forma oral y es conocido por su perfil de toxicidad relativamente bajo en comparación con otros antipalúdicos. Su estructura química incluye un grupo 4-aminoquinolina, que es esencial para su actividad farmacológica. La forma de sal sulfato mejora su solubilidad y estabilidad. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, reacciones cutáneas y, en casos raros, toxicidad retinal con el uso prolongado. Debido a sus efectos inmunomoduladores, la hidroxicloroquina ha ganado atención en varios usos no aprobados, particularmente en enfermedades autoinmunes. Sin embargo, su eficacia y seguridad en estos contextos continúan siendo objeto de investigación y evaluación clínica en curso.

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

InChI: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

Clave InChI: InChIKey=JCBIVZZPXRZKTI-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.N(C(CCCN(CCO)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2

Sinónimos:

• 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate
• 2-([4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino)ethan-1-ol; sulfuric acid
• 7-Chloro-4-[4-N-ethyl-N-beta-hydroxyethylamino-1-methylbutylamino]quinoline sulfate
• 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline sulfate
• 7-chloro-4-({(1R)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• 7-chloro-4-({(1S)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• Ercoquin
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1)
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Hydrochloroquine Sulfate
• Hydroxy chloroquine sulfate
• Hydroxychloroquine sulfate
• NSC 4375
• Plaquenil
• Plaquenil sulfate
• Quensyl

Hydroxychloroquine Sulfate

CAS: 118-42-3, 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 433.95

Ref: 3B-H1306

HYDROXYCHLOROQUINE SULFATE CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE SULFATE CRS

Fórmula: C₁₈H₂₈ClN₃O₅S

Forma y color: Modified

Peso molecular: 433.95

Ref: 41-Y0001839

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₈H₂₈ClN₃O₅S

Forma y color: White. Whitish. Crystalline Powder.

Peso molecular: 433.95

Ref: 41-Y0001841

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Fórmula: C₁₈H₂₆CIN₃OH₂SO₄

Pureza: 99.7%

Forma y color: White. To. Off-White

Peso molecular: 537.07944

Ref: 47-1100

Hydroxychloroquine Sulfate

CAS: 747-36-4

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Forma y color: White Off-White Crystalline Powder

Peso molecular: 433.14382

Ref: 45-1327000

Hydroxychloroquine sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: 99%

Forma y color: Solid

Peso molecular: 433.9500

Ref: IN-DA0059P3

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: 98.92% - 99.88%

Forma y color: White Solid

Peso molecular: 433.95

Ref: TM-T0951

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: ≥98%

Peso molecular: 433.95

Ref: 54-BUP16035

Hydroxychloroquine sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 433.95

Ref: 7W-GK2606

Hydroxychloroquine Sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Forma y color: White To Off-White Solid

Peso molecular: 335.88 98.07

Ref: 4Z-H-061

Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base)

CAS: 747-36-4

Forma y color: Single Solution

Ref: 61-AMP0764.00-01

Hydroxychloroquine Sulphate

CAS: 747-36-4

Forma y color: Neat

Ref: 86-MM0764.00

Hydroxychloroquine sulfate (Standard)

CAS: 747-36-4

Hydroxychloroquine sulfate (Standard) is a reference standard for research and analysis in studies involving Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa.

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Peso molecular: 433.95

Ref: TM-TMSM-3523

Hydroxychloroquine Sulphate

CAS: 747-36-4

Forma y color: Neat

Ref: 61-FOR0764.00

Hydroxychloroquine sulfate

CAS: 747-36-4

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: 99%

Peso molecular: 433.95

Ref: IN-DG134190

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Fórmula: C₁₈H₂₆ClN₃O·H₂SO₄

Pureza: 99%

Forma y color: Solid

Peso molecular: 433.95002

Ref: 54-BISN0145

Hydroxychloroquine Sulfate

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃OH₂SO₄

Peso molecular: 335.9 : 98.1

Ref: ST-EA-CP-H4012

Hydroxychloroquine Sulfate

Producto controlado

CAS: 747-36-4

Fórmula: C₁₈H₂₆ClN₃O·H₂O₄S

Forma y color: Neat

Peso molecular: 433.95

Ref: TR-H916900

Hydroxychloroquine sulfate - Bio-X ™

CAS: 747-36-4

Hydroxychloroquine is a drug that is used to treat multiple types of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus and discoid lupus. It is a prodrug, which is activated in the liver to hydroxychloroquine. It inhibits the production of inflammatory cytokines and nitric oxide by binding to the toll-like receptor 4 (TLR4) and inhibiting signaling pathways downstream of TLR4 activation. Additionally, Hydroxychloroquine is used to prevent and treat malaria caused by parasitic protozoan from the Plasmodium genus. Furthermore, recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Fórmula: C₁₈H₂₈ClN₃O₅S

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 433.95 g/mol

Ref: 3D-BH164525

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Hydroxychloroquine is also used to treat non-infectious diseases such as rheumatoid arthritis and lupus thanks to its immunomodulatory properties. Recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Fórmula: C₁₈H₂₆ClN₃O•H₂SO₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 433.95 g/mol

Ref: 3D-FH24322