CAS 751-03-1

Obacunona

Descripción:

Obacunona es un compuesto natural clasificado como un limonoide, derivado principalmente de las semillas del fruto del género Citrus, particularmente de la especie Citrus Obacunona. Se caracteriza por su compleja estructura tetracíclica, que incluye un sistema de anillos fusionados que contribuye a su actividad biológica. Obacunona exhibe una variedad de propiedades farmacológicas, incluyendo efectos antiinflamatorios, anticancerígenos y antimicrobianos, lo que lo convierte en un tema de interés en la química medicinal y la investigación de productos naturales. El compuesto se encuentra típicamente en bajas concentraciones en frutas cítricas, y su extracción y purificación pueden ser desafiantes debido a su complejidad estructural. En términos de propiedades físicas, Obacunona es generalmente un sólido incoloro a amarillo pálido con un olor característico. Su solubilidad varía, siendo más soluble en disolventes orgánicos que en agua. El estudio de Obacunona continúa revelando sus posibles aplicaciones en productos farmacéuticos y alimentos funcionales, destacando la importancia de los compuestos naturales en el descubrimiento y desarrollo de fármacos.

Fórmula: C₂₆H₃₀O₇

InChI: InChI=1S/C26H30O7/c1-22(2)16-12-17(27)25(5)15(23(16,3)9-7-18(28)32-22)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)33-20/h7-9,11,13,15-16,19-20H,6,10,12H2,1-5H3/t15-,16+,19+,20-,23-,24+,25+,26-/m1/s1

Clave InChI: InChIKey=MAYJEFRPIKEYBL-OASIGRBWSA-N

SMILES: C[C@]12[C@]34[C@](O3)(C(=O)O[C@H]([C@]4(C)CC[C@@]1([C@]5(C)[C@@](CC2=O)(C(C)(C)OC(=O)C=C5)[H])[H])C=6C=COC6)[H]

Sinónimos:

• (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione
• (5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione
• (5aR,7aS,8R,10aS,11aR,11bR)-8-(furan-3-yl)-12,12-dihydroxy-1,1,5a,7a,11b-pentamethyl-5a,5b,6,7,7a,8,11b,12,13,13a-decahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10(1H,10aH)-dione
• 14,15:21,23-Diepoxy-4,4,8-trimethyl-A,<span class="text-smallcaps">D</span>-dihomo-24-nor-4,17-dioxachola-1,20,22-triene-3,7,16-trione
• Ai3-37934
• Ccris 8657
• Obacunoic acid 3,4-lactone
• Obacunoic acid, eta-lactone
• Obacunoic acid, ε-lactone
• Obacunon
• Obakunone
• Oxireno(4,4a)-2-benzopyrano(6,5-g)(2)benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione, 1-(3-furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyl-, [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-
• Oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aαH,4bH,6H)-trione, 1α-(3-furyl)-1,6aα,7,11a,11bα,12,13,13a-octahydro-4bβ,7,7,11aβ,13aα-pentamethyl-
• Tricoccin S₃
• [1S-(1α,3aα,4aS*,4bβ,6aα,11aβ,11bα,13aα)]-1-(3-Furanyl)-1,6a,7,11a,11b,12,13,13a-octahydro-4b,7,7,11a,13a-pentamethyloxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Pureza: >98.0%(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 454.52

Ref: 3B-O0506

Obacunone

CAS: 751-03-1

Obacunone

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Peso molecular: 454.51

Ref: 54-OR1023060

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: 7W-GY8065

Obacunone

CAS: 751-03-1

Obacunone

Fórmula: C₂₆H₃₀O₇

Pureza: 99.5%

Forma y color: Solid

Peso molecular: 454.51

Ref: 54-BUP10739

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Forma y color: Solid

Peso molecular: 454.5122

Ref: IN-DA00G2A6

Obacunone (Standard)

CAS: 751-03-1

Obacunone (Standard) is a reference standard for research and analysis in studies involving Obacunone. Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typhimurium. Obacunone may have the potential to prevent estrogen-responsive breast Y through inhibition of the aromatase enzyme and inflammatory pathways, as well as activation of apoptosis.

Fórmula: C₂₆H₃₀O₇

Forma y color: Solid

Peso molecular: 454.5122

Ref: TM-TMSM-1938

Obacunone

CAS: 751-03-1

Obacunone is a novel activator of Nrf2, which exhibits anti-cancer, anti-inflammatory, antivirulence, insecticidal, anti-proliferative and anti-aromatase activities. Obacunone stimulates muscle hypertrophy and prevents obesity and hyperglycemia, and that these beneficial effects are likely to be mediated through the activation of TGR5 and inhibition of PPARγ transcriptional activity. Obacunone significantly inhibits aromatase activity in an in vitro enzyme assay with an IC50 value of 28.04 μM, and it also inhibits the p38 MAPK signaling pathway.

Fórmula: C₂₆H₃₀O₇

Pureza: 95%~99%

Peso molecular: 454.519

Ref: BP-BP1018

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: 4Z-O-086001

Obacunone

CAS: 751-03-1

Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.

Fórmula: C₂₆H₃₀O₇

Pureza: 98% - ≥95%

Forma y color: White Powder

Peso molecular: 454.5122

Ref: TM-T3390

Obacunone

CAS: 751-03-1

(1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione

Fórmula: C₂₆H₃₀O₇

Pureza: 98%

Peso molecular: 454.51

Ref: IN-DG299914

Obacunone

CAS: 751-03-1

Lactone

Fórmula: C₂₆H₃₀O₇

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 454.52

Ref: 5G-80509

Obacunone

CAS: 751-03-1

Obacunone is a naturally occurring limonoid, which is a type of triterpenoid compound. It is derived from the peels of citrus plants, particularly bitter and sweet oranges. Obacunone operates through several mechanisms, including inducing apoptosis, inhibiting cell proliferation, and modulating various signaling pathways. Its biological activity has garnered attention for its potential therapeutic benefits.

Fórmula: C₂₆H₃₀O₇

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 454.51 g/mol

Ref: 3D-FO65314

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.5

Ref: BE-RMT12350

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.5

Ref: BE-RMCO001000

OBACUNONE

CAS: 751-03-1

Pureza: 98%

Peso molecular: 454.5190125

Ref: 10-F795475

Obacunone

CAS: 751-03-1

Fórmula: C₂₆H₃₀O₇

Peso molecular: 454.52

Ref: ST-EA-CP-O89000