CAS 7681-93-8

Natamicina

Descripción:

Natamicina, también conocido como pimaricina, es un antibiótico macrólido polieno que se utiliza principalmente como conservante natural en alimentos y como agente antifúngico en diversas aplicaciones. Se produce mediante la fermentación de ciertas especies de Streptomyces. Natamicina se caracteriza por su capacidad para inhibir el crecimiento de una amplia gama de hongos y levaduras, lo que lo hace particularmente efectivo para prevenir el deterioro en productos lácteos, carnes y productos horneados. El compuesto actúa uniéndose a los esteroides en la membrana celular fúngica, interrumpiendo la integridad de la membrana y llevando a la muerte celular. Natamicina es generalmente reconocido como seguro (GRAS) para su uso en alimentos, y su eficacia se ve potenciada por su baja solubilidad en agua, lo que permite una acción prolongada. Además de sus aplicaciones en la conservación de alimentos, Natamicina también se utiliza en productos farmacéuticos, particularmente en el tratamiento de infecciones fúngicas en humanos y animales. Su estructura química presenta un gran anillo de lactona y múltiples enlaces dobles conjugados, lo que contribuye a su actividad biológica y estabilidad bajo diversas condiciones.

Fórmula: C₃₃H₄₇NO₁₃

InChI: InChI=1/C33H47NO13/c1-18-10-8-6-4-3-5-7-9-11-21(45-32-30(39)28(34)29(38)19(2)44-32)15-25-27(31(40)41)22(36)17-33(42,47-25)16-20(35)14-24-23(46-24)12-13-26(37)43-18/h3-9,11-13,18-25,27-30,32,35-36,38-39,42H,10,14-17,34H2,1-2H3,(H,40,41)/b4-3+,7-5+,8-6-,11-9+,13-12+/t18-,19-,20+,21+,22+,23-,24-,25+,27-,28+,29-,30+,32?,33-/m1/s1

Clave InChI: InChIKey=NCXMLFZGDNKEPB-FFPOYIOWSA-N

SMILES: C(O)(=O)[C@H]1[C@]2(O[C@@](O)(C[C@@H]1O)C[C@@H](O)C[C@@]3([C@](O3)(/C=C/C(=O)O[C@H](C)C\C=C\C=C\C=C\C=C\[C@H](O[C@H]4[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O4)C2)[H])[H])[H]

Sinónimos:

• (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-Amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-beta-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (1R,3S,5R,7R,8E,12R,22R,24S,25R,26S)-22-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• (8Z,14Z,16Z,18Z,20Z)-22-[(3-amino-3,6-dideoxyhexopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• 22-[(3-amino-3,6-dideoxy-beta-D-glycero-hexopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0~5,7~]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-
• 6,11,28-Trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, (1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid, 22-[(3-amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-, [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-
• 6,11,28-Trioxatricyclo[22.3.1.0^5,7]octacosane, pimaricin deriv.
• Antibiotic A 5283
• Cl 12625
• Delvocid
• E 235
• Mycophyt
• Myprozine
• Myuprozine
• Natacyn
• Natajen
• Natamatrix
• Natamax
• Natamax SF
• Natamax lactose
• Natamicina
• Natamycin
• Natamycin Sterile
• Natamycine
• Pimaricin
• Pimaricin, Streptomyces chattanoogensis (1.07360)
• Synogil
• Tennecetin
• [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-<span class="text-smallcaps">D</span>-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• [1R-(1R*,3S*,5R*,7R*,8E,12R*,14E,16E,18E,20E,22R*,24S*,25R*,26S*)]-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• δ-Natamycin

Natamycin, 95%

CAS: 7681-93-8

Natamycin, 7681-93-8, also known as pimaricin, is a polyene macrolide antibiotic isolated from Streptomyces natalensis which exhibits antifungal properties. Learn more.

Fórmula: C₃₃H₄₇NO₁₃

Pureza: 95%

Forma y color: White to pale yellow to pale brown, Powder or crystals

Peso molecular: 665.73

Ref: 02-J66468

Natamycin

CAS: 7681-93-8

Antibiotics nesoi

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: Off-White Cream Powder

Peso molecular: 665.30474

Ref: 45-1457505

Pimaricin

CAS: 7681-93-8

Pimaricin

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: Solid

Peso molecular: 665.72518

Ref: 54-BIP0144

Natamycin

CAS: 7681-93-8

Natamycin (Pimaricin) is a Polyene Antimicrobial.

Fórmula: C₃₃H₄₇NO₁₃

Pureza: 98.73% - 99.65%

Forma y color: Solid

Peso molecular: 665.7252

Ref: TM-T0709

Natamycin

CAS: 7681-93-8

Natamycin

Fórmula: C₃₃H₄₇NO₁₃

Pureza: ≥95%

Forma y color: Liquid

Peso molecular: 665.73

Ref: 54-BUP15815

Natamycin

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Peso molecular: 665.73

Ref: 4Z-N-158001

Pimaricin

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Pureza: ≥ 95.0% (dried basis)

Forma y color: White to yellow powder

Peso molecular: 665.7

Ref: 7W-GA5100

(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Pureza: 96%

Forma y color: Solid

Peso molecular: 665.7252

Ref: IN-DA00IKIX

Natamycin (Standard)

CAS: 7681-93-8

Natamycin (Standard) is the standard substance of Natamycin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Natamycin (Pimaricin) is a Polyene Antimicrobial.

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: Solid

Peso molecular: 665.7252

Ref: TM-TMSM-1707

Pimaricin

Producto controlado

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: Neat

Peso molecular: 665.73

Ref: 04-C16208400

Natamycin

CAS: 7681-93-8

Stability Hygroscopic, Light Sensitive
Applications Polyene antifungal antibiotic.
References Levinskas, G.J., et al.: Toxicol. Appl. Pharmacol., 8, 97 (1966), Pandey, R.C., et al.: J. Antibiot., 29, 1035 (1976), Brik, H., et al.: Anal. Profiles Drug Subs. Excip., 23, 399 (1994),

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: Neat

Peso molecular: 665.73

Ref: TR-N379100

Natamycin

CAS: 7681-93-8

(1R,3S,5R,7R,8E,12R,14E,16E,18E,20E,22R,24S,25R,26S)-22-(((2R,3S,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid

Fórmula: C₃₃H₄₇NO₁₃

Pureza: 98%

Peso molecular: 665.73

Ref: IN-DG143366

Natamycin RS

CAS: 7681-93-8

Forma y color: White To Yellow-White Solid Crystalline Powder

Ref: 2K-501500002

Natamycin

CAS: 7681-93-8

Natamycin is a polyene macrolide antifungal agent with action on fungal cell membranes by binding to sterols and is used for treating fungal infections and as a food preservative.

Fórmula: C₃₃H₄₇NO₁₃

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 665.73 g/mol

Ref: 3D-AN26164

Natamycin

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Peso molecular: 665.7

Ref: ST-EA-CP-N58000

Pimaricin

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: White to creamy-white crystalline powder

Peso molecular: 665.7

Ref: BE-BePure-25079

Pimaricin in Methanol

CAS: 7681-93-8

Methanol

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: White to creamy-white crystalline powder

Peso molecular: 665.7

Ref: BE-BePure-25079YM-1000

Pimaricin in Methanol

CAS: 7681-93-8

Methanol

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: White to creamy-white crystalline powder

Peso molecular: 665.7

Ref: BE-BePure-25079ZM-500

Natamycin

CAS: 7681-93-8

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: White to creamy-white crystalline powder

Peso molecular: 665.7

Ref: BE-RMCN035000

Pimaricin in Methanol

CAS: 7681-93-8

Methanol

Fórmula: C₃₃H₄₇NO₁₃

Forma y color: White to creamy-white crystalline powder

Peso molecular: 665.7

Ref: BE-BePure-25079XM-100