CAS 81839-27-2

Fórmula: C7H12Cl2FN3O2

InChI: InChI=1S/C7H10FN3O2.2ClH/c8-3-7(9,6(12)13)1-5-2-10-4-11-5;;/h2,4H,1,3,9H2,(H,10,11)(H,12,13);2*1H/t7-;;/m1../s1

Clave InChI: LIJUCORJKQZTOS-XCUBXKJBSA-N

SMILES: C1=C(NC=N1)C[C@@](CF)(C(=O)O)N.Cl.Cl

(S)-(+)-α-Fluoromethylhistidine dihydrochloride

CAS: 81839-27-2

(S)-(+)-a-Fluoromethylhistidine dihydrochloride is a maleate salt of (S)-(+)-a-fluoromethylhistidine that has been shown to have analgesic effects in rats. According to the plate test, the antinociceptive effect of (S)-(+)-a-fluoromethylhistidine dihydrochloride is dose-dependent and can be antagonized by histamine. Histamine levels were found to be statistically significantly elevated in response to the administration of (S)-(+)-a-fluoromethylhistidine dihydrochloride, suggesting that its antinociceptive effect may be due to an endogenous histamine release. The antagonist activity of this compound was also confirmed in vivo by blocking the modulatory effect of histamine on abdominal contractions in rats.

Fórmula: C₇H₁₀FN₃O₂•(HCl)₂

Pureza: Min. 95%

Peso molecular: 260.09 g/mol

Ref: 3D-FF158608

(S)-α-Fluoromethylhistidine 2 HCl

CAS: 81839-27-2

(S)-alpha-Fluoromethylhistidine 2 HCl is a potent irreversible inhibitor of histidine decarboxylase (HDC) and glutathione S-transferase.

Fórmula: C₇H₁₁ClFN₃O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 223.63

Ref: TM-T26374