CAS: 82964-04-3 - Tolrestat

Fórmula: C₁₆H₁₄F₃NO₃S

InChI: InChI=1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)

Clave InChI: InChIKey=LUBHDINQXIHVLS-UHFFFAOYSA-N

SMILES: O=C(O)CN(C(=S)C1=CC=CC=2C1=CC=C(OC)C2C(F)(F)F)C

Sinónimos:

• 2-(6-Methoxy-N-methyl-5-(trifluoromethyl)naphthalene-1-carbothioamido)aceticacid
• Alredase
• Ay 27773
• Glycine, N-((6-methoxy-5-(trifluoromethyl)-1-naphthalenyl)thioxomethyl)-N-methyl-
• Lorestat
• N-(6-Methoxythio-5-(trifluoromethyl)-1-naphthoyl)sarcosine
• N-[[6-Methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methylglycine
• N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]carbothioyl}-N-methylglycine
• Tolrestat [USAN:INN:BAN]
• Tolrestatin
• Tolrestatum
• Tolrestatum [Latin]

TOLRESTAT

CAS: 82964-04-3

• Fórmula: C₁₆H₁₄F₃NO₃S
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 357.3475

Tolrestat

CAS: 82964-04-3

• Fórmula: C₁₆H₁₄F₃NO₃S
• Peso molecular: 357.35

Tolrestat

CAS: 82964-04-3

Tolrestat (AY-27773) is a potent inhibitor of aldose reductase (IC50 = 35 nM).

• Fórmula: C₁₆H₁₄F₃NO₃S
• Pureza: 100%
• Forma y color: Solid
• Peso molecular: 357.35

Tolrestat

CAS: 82964-04-3

Applications Tolrestat is an aldose reductase inhibitor. References Fortes, Z.B., et. al.: Gen. Pharmacol., 27, …

• Fórmula: C₁₆H₁₄F₃NO₃S
• Forma y color: White to Light Yellow Solid
• Peso molecular: 357.35

Tolrestat

CAS: 82964-04-3

Aldose reductase AKR1B10 inhibitor; hepatotoxic

• Fórmula: C₁₆H₁₄F₃NO₃S
• Pureza: Min. 95%
• Peso molecular: 357.35 g/mol

Tolrestat-d3

CAS: 82964-04-3

• Fórmula: C₁₆H₁₁D₃F₃NO₃S
• Peso molecular: 360.37