CAS 834-28-6
:clorhidrato de fenformina
Descripción:
clorhidrato de fenformina es un compuesto farmacéutico utilizado principalmente como agente antidiabético, que pertenece a la clase de medicamentos biguanidas. Se caracteriza por su capacidad para reducir los niveles de glucosa en sangre al mejorar la sensibilidad a la insulina y reducir la producción hepática de glucosa. El compuesto se presenta típicamente como un polvo cristalino blanco a blanco amarillento, que es soluble en agua y exhibe un sabor ligeramente amargo. Su estructura química incluye un grupo fenilo, que contribuye a sus propiedades farmacológicas. clorhidrato de fenformina se ha asociado con efectos secundarios gastrointestinales y, en algunos casos, acidosis láctica, lo que ha llevado a su retirada del mercado en muchos países. A pesar de su uso histórico, es importante señalar que su perfil de seguridad ha suscitado preocupaciones, lo que ha llevado al desarrollo de medicamentos alternativos con mejor seguridad y eficacia. Al igual que con cualquier agente farmacéutico, la dosificación adecuada y el monitoreo son esenciales para minimizar riesgos y maximizar beneficios terapéuticos.
Fórmula:C10H16ClN5
InChI:InChI=1/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
Clave InChI:InChIKey=YSUCWSWKRIOILX-UHFFFAOYSA-N
SMILES:C(CNC(NC(=N)N)=N)C1=CC=CC=C1.Cl
Sinónimos:- 1-(2-Phenylethyl)biguanide hydrochloride
- 1-(Diaminomethylidene)-2-(2-Phenylethyl)Guanidine Hydrochloride (1:1)
- 1-Phenethylbiguanide hydrochloride
- 1-β-Phenylethylbiguanide hydrochloride
- Azucaps
- Biguanide, 1-phenethyl-, monohydrochloride
- Dbi-Td
- Debeone DT
- Debinyl
- Dibein
- Dipar
- Feguanide
- Glucopostin
- Imidodicarbonimidic diamide, N-(2-phenylethyl)-, hydrochloride (1:1)
- Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
- Insoral
- Lentobetic
- Meltrol
- N-Phenethylbiguanide hydrochloride
- Normoglucina
- N′-β-Phenylethylbiguanide-hydrochloride
- Phenethylbiguanide hydrochloride
- Phenformin Hcl
- Phenformine HCL
- α-Phenethylbiguanide hydrochloride
- n-beta-phenylethylbiguanidehydrochloride
- 1-fenetilbiguanidecloridrato
- n’-beta-phenethylbiguanidehydrochloride
- 1-phenethyl-biguanidhydrochloride
- phenoforminehydrochloride
- phenforminhclno.9113
- PHENFORMIN HYDROCHLORIDE
- n-(2-phenylethyl)-imidodicarbonimidicdiamidmonohydrochloride
- usafvi-6
- 1-phenethyl-biguanidmonohydrochloride
- PHENFORMINI HYDROCHLORIDE
- Insora
- 1-phenylaethylbiguanidhydrochlorid
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Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Forma y color:White SolidPeso molecular:241.72Phenformin Hydrochloride
CAS:Phenformin HydrochlorideFórmula:C10H16ClN5Pureza:98%Forma y color:SolidPeso molecular:241.72Phenformin hydrochloride
CAS:Phenformin hydrochlorideFórmula:C10H16ClN5Pureza:≥95%Forma y color:SolidPeso molecular:241.72Phenformin HCl
CAS:Fórmula:C10H15N5·HClForma y color:White To Off-White SolidPeso molecular:205.27 36.46Phenformin Hydrochloride
CAS:Fórmula:C10H15N5·ClHForma y color:White To Off-WhitePeso molecular:241.72Phenformin Hydrochloride
CAS:Producto controladoFórmula:C10H15N5·ClHForma y color:NeatPeso molecular:241.72Imidodicarbonimidic diamide, N-(2-phenylethyl)-, monohydrochloride
CAS:Fórmula:C10H16ClN5Pureza:97%Forma y color:SolidPeso molecular:241.7205Phenformin-d5 Hydrochloride
CAS:Producto controladoApplications Isotope labelled Phenformin It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),Fórmula:C10D5H10N5·ClHForma y color:NeatPeso molecular:246.751Phenformin Hydrochloride
CAS:Applications It is an anti-diabetic drug from the biguanide class.
References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),Fórmula:C10H15N5·ClHForma y color:NeatPeso molecular:241.721-Carbamimidamido-N-(2-phenylethyl)methanimidamide Hydrochloride
CAS:Fórmula:C10H16ClN5Pureza:98%Peso molecular:241.72N-(2-phenylethyl)imidodicarbonimidic diamide hydrochloride
CAS:Fórmula:C10H16ClN5Pureza:97%Forma y color:SolidPeso molecular:241.72Phenformin hydrochloride
CAS:Phenformin hydrochloride is a phenformin derivative that is used as an oral hypoglycemic. It has been shown to inhibit the synthesis of fatty acids in the liver and to reduce the size of lipid droplets, which are a hallmark of hepatic steatosis. Phenformin hydrochloride also inhibits the polymerase chain reaction and mitochondrial membrane potential, which results in reduced oxidative stress and apoptosis. This drug has been shown to have anti-infectious effects against infectious diseases such as typhoid fever, tuberculosis, and malaria. Phenformin hydrochloride may also be carcinogenic, due to its ability to induce skin cancer in mice with a genetic predisposition for this type of cancer. The drug should not be administered to patients with metabolic disorders or patients who are receiving chemotherapy agents that affect cell proliferation because it can exacerbate these conditions.Fórmula:C10H16ClN5Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:241.72 g/mol
