CAS 84529-86-2

Fórmula: C30H54O2Si

InChI: InChI=1S/C30H54O2Si/c1-21(10-9-19-31)25-13-14-26-24-12-11-22-20-23(32-33(7,8)28(2,3)4)15-17-29(22,5)27(24)16-18-30(25,26)6/h11,21,23-27,31H,9-10,12-20H2,1-8H3/t21-,23+,24+,25-,26+,27+,29+,30-/m1/s1

Clave InChI: YORJZEWEGWVASD-NXUCFJMCSA-N

SMILES: C[C@H](CCCO)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O[Si](C)(C)C(C)(C)C)C)C

(3Beta)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol

Producto controlado

CAS: 84529-86-2

Applications (3β)-3-O-tert-Butyldimethylsilyl-cholest-5-ene-3,24-diol is a reactant used in the preparation of series of cholesterol side-chain analogs used in studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P 450 enzymes. It is used in the preparation of (25S)-Δ7-dafachronic acid, (25S)-Δ4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid.
References Johnston, J. et al.: Bioorg. Med. Chem., 20, 4064 (2012); Martin, R. et al.: Org. Biomol. Chem., 6, 4293 (2008)

Fórmula: C₃₀H₅₄O₂Si

Forma y color: Neat

Peso molecular: 474.83

Ref: TR-B692060