
CAS 847163-28-4
:Fórmula:C15H11N3O
InChI:InChI=1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3
Clave InChI:DYXYXTDIFMDJIR-UHFFFAOYSA-N
SMILES:CNC1=C(N=C(O1)C2=CC=CC3=CC=CC=C32)C#N
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ML351
CAS:5-(Methylamino)-2-(naphthalen-1-yl)oxazole-4-carbonitrileFórmula:C15H11N3OPureza:98%Peso molecular:249.27ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Fórmula:C15H11N3OPureza:97.67%Forma y color:White SolidPeso molecular:249.2673ML351
CAS:ML351 is a resolvin, which are lipid mediators that serve as precursors to other compounds. Resolvins have been shown to be active in the central nervous system and cardiovascular system. ML351 binds to an enzyme that is required for the production of these mediators. This binding prevents the enzyme from converting arachidonic acid into prostaglandin H2, leading to irreversible inhibition of this enzyme. ML351 has been shown to inhibit the inflammatory response in cells by preventing the production of pro-inflammatory molecules such as prostaglandins and platelet-activating factor (PAF). It also has potential drug targets in congestive heart failure, cardiac hypertrophy, and nonsteroidal anti-inflammatory drugs.Fórmula:C15H11N3OPureza:Min. 95%Peso molecular:249.27 g/mol




