CAS 866914-87-6

Fórmula: C20H22Cl3N3S

InChI: InChI=1S/C20H20ClN3S.2ClH/c21-17-4-1-3-16(13-17)14-23-11-10-15-6-8-18(9-7-15)24-20(22)19-5-2-12-25-19;;/h1-9,12-13,23H,10-11,14H2,(H2,22,24);2*1H

Clave InChI: SOXBYIKSUDXMIE-UHFFFAOYSA-N

SMILES: C1=CC(=CC(=C1)Cl)CNCCC2=CC=C(C=C2)N=C(C3=CC=CS3)N.Cl.Cl

ARL 17477

CAS: 866914-87-6

Fórmula: C₂₀H₂₂Cl₃N₃S

Pureza: 99.02%

Peso molecular: 442.8328

Ref: IN-DA01E5K9

ARL-17477 dihydrochloride hydrate

CAS: 866914-87-6

Fórmula: C₂₀H₂₀ClN₃S·2HCl·xH₂O

Peso molecular: 442.83 (anhydrous)

Ref: 7W-GL6359

ARL 17477 Dihydrochloride

Producto controlado

CAS: 866914-87-6

ARL 17477 is a potent and selective pharmacological inhibitor of guanylate cyclase (GC) that was developed for use in animal research. It inhibits the production of pro-inflammatory cytokines and has been shown to decrease the incidence of spontaneous tumors in animals. ARL 17477 inhibits GC by binding reversibly to the enzyme's active site, preventing the conversion of GTP to cGMP, which is required for cell proliferation. ARL 17477 also inhibits magnesium-dependent polymerase chain reaction (PCR), leading to decreased levels of DNA synthesis, cell proliferation, and tissue staining.

Fórmula: C₂₀H₂₀ClN₃S•(HCl)₂

Pureza: Min. 95%

Peso molecular: 369.91 g/mol

Ref: 3D-RJB91487