CAS 878489-28-2

Fórmula: C21H29ClN2O4S

InChI: InChI=1S/C21H29ClN2O4S/c1-20(2,28-17-6-4-16(22)5-7-17)19(25)23-18-14-8-13-9-15(18)12-21(10-13,11-14)24-29(3,26)27/h4-7,13-15,18,24H,8-12H2,1-3H3,(H,23,25)/t13?,14-,15+,18?,21?

Clave InChI: OSGIRCJRKSAODN-DJASPMHUSA-N

SMILES: CC(C)(C(=O)NC1[C@@H]2CC3C[C@H]1CC(C2)(C3)NS(=O)(=O)C)OC4=CC=C(C=C4)Cl

Rel-2-(4-Chlorophenoxy)-2-Methyl-N-((1S,2R)-5-(Methylsulfonamido)Adamantan-2-Yl)Propanamide

CAS: 878489-28-2

Rel-2-(4-Chlorophenoxy)-2-Methyl-N-((1S,2R)-5-(Methylsulfonamido)Adamantan-2-Yl)Propanamide

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: 98%

Peso molecular: 440.98

Ref: 54-OR1022992

JNJ 303

CAS: 878489-28-2

JNJ 303

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: 99%

Peso molecular: 440.98

Ref: 54-BUP03061

rel-2-(4-Chlorophenoxy)-2-methyl-N-((1S,2R)-5-(methylsulfonamido)adamantan-2-yl)propanamide

CAS: 878489-28-2

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: 98%

Forma y color: Solid

Peso molecular: 440.9840

Ref: IN-DA008CKG

rel-2-(4-Chlorophenoxy)-2-methyl-N-((1S,2R)-5-(methylsulfonamido)adamantan-2-yl)propanamide

CAS: 878489-28-2

rel-2-(4-Chlorophenoxy)-2-methyl-N-((1S,2R)-5-(methylsulfonamido)adamantan-2-yl)propanamide

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: 98%

Peso molecular: 440.98

Ref: IN-DG01131397

JNJ 303

CAS: 878489-28-2

JNJ 303 is a potent blocker of IKs (IC50 : 64 nM).

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: 99.28%

Forma y color: Solid

Peso molecular: 440.984

Ref: TM-T7653

JNJ 303

CAS: 878489-28-2

JNJ 303 is a drug that belongs to the class of molecular models. It is used in model studies with anesthetized animals and as a molecular modelling agent for cardiac arrhythmias. JNJ 303 has been shown to have proarrhythmic effects on the heart and to cause ectopic expression of Kv1.5 potassium channels in the heart, leading to increased cardiac excitability. This drug has also been shown to have electrophysiological properties, such as prolonging action potential duration and increasing refractory periods. The subunit interactions between JNJ 303 and Kv1.5 channels are validated by computational simulations.

Fórmula: C₂₁H₂₉ClN₂O₄S

Pureza: Min. 95%

Peso molecular: 440.98 g/mol

Ref: 3D-DKB48928