
CAS 915082-52-9
:PDE4B-IN-2
CAS:2-(4-((2-(5-Chlorothiophen-2-yl)-5-ethyl-6-methylpyrimidin-4-yl)amino)phenyl)acetic acidFórmula:C19H18ClN3O2SPureza:99%Peso molecular:387.88A 33
CAS:A 33 is a polymeric matrix that is programmable and can be used to create an osmotic device. It consists of a fibre with a cyclic oligomeric matrix (COM) that is hydrophilic on one side and hydrophobic on the other. The two surfaces are connected by a membrane. The COM is designed to change the pH of the solution on either side, depending on the desired effect. For example, if it is desirable for the system to maintain a basic pH, then the hydrophobic side should be placed in contact with an acidic solution, while the hydrophilic side should be placed in contact with a basic solution. This produces an osmotic system that has different properties at different pH levels. A 33 has been tested as a treatment for systemic sclerosis and has shown promising results in animal models.
Fórmula:C19H18ClN3O2SPureza:Min. 95%Peso molecular:387.9 g/molPDE4B-IN-2
CAS:PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.Fórmula:C19H18ClN3O2SPureza:99.32%Forma y color:Yellow SolidPeso molecular:387.88Ref: TM-T36832
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg105,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€




