CAS 924811-53-0

Fórmula: C30H31F4N3O6S

InChI: InChI=1S/C30H31F4N3O6S/c1-41-26-7-5-22(44(39,40)37-9-8-19-14-27(42-2)28(43-3)15-20(19)18-37)17-25(26)35-10-12-36(13-11-35)29(38)23-6-4-21(31)16-24(23)30(32,33)34/h4-7,14-17H,8-13,18H2,1-3H3

Clave InChI: QVIIZVVDZZHGCB-UHFFFAOYSA-N

SMILES: COC1=C(C=C(C=C1)S(=O)(=O)N2CCC3=CC(=C(C=C3C2)OC)OC)N4CCN(CC4)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F

BT18

CAS: 924811-53-0

BT18 mimics GDNF, affecting RET receptor tyrosine kinase RetA and GFRα1 function.

Fórmula: C₃₀H₃₁F₄N₃O₆S

Pureza: 99.32%

Forma y color: White Solid

Peso molecular: 637.642

Ref: TM-T13587

BT18

CAS: 924811-53-0

BT18

Fórmula: C₃₀H₃₁F₄N₃O₆S

Pureza: ≥98%

Peso molecular: 637.64

Ref: 54-BUP04545

(4-(5-((6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone

CAS: 924811-53-0

Fórmula: C₃₀H₃₁F₄N₃O₆S

Forma y color: Solid

Peso molecular: 637.6423

Ref: IN-DA01V4FB

BT 18

CAS: 924811-53-0

Activator of RET signalling cascade and a derivative of a GFL mimetic compound BT 13. Molecular docking calculations and molecular dynamics simulations were performed in GDNF−GFRα1−RetA complex and showed that BT 18 binds to the allosteric site in GFRα1 as well as RetA surface interfacing GFRα1.

Fórmula: C₃₀H₃₁F₄N₃O₆S

Pureza: Min. 95%

Forma y color: Solid

Peso molecular: 637.64 g/mol

Ref: 3D-BB170419