EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 582 productos de "EGFR"
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PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51Ref: TM-T23127
1mg34,00€5mg96,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€1mL*10mM (DMSO)118,00€Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Fórmula:C30H34N8O3Pureza:98.7% - 99.90%Forma y color:SolidPeso molecular:554.64Ref: TM-T4485
1mg46,00€2mg59,00€5mg96,00€10mg130,00€25mg215,00€50mg309,00€100mg444,00€200mg655,00€1mL*10mM (DMSO)104,00€Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Fórmula:C11H8N2OPureza:98.32%Forma y color:SolidPeso molecular:184.19WZ4002
CAS:WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97Ref: TM-T6238
2mg34,00€5mg49,00€10mg70,00€25mg111,00€50mg177,00€100mg313,00€200mg464,00€1mL*10mM (DMSO)50,00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38Gefitinib-based PROTAC 3
CAS:Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Fórmula:C47H57ClFN7O8SPureza:97.29% - 98.25%Forma y color:SolidPeso molecular:934.51Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFórmula:C24H27ClFN5O3Pureza:99.52%Forma y color:SolidPeso molecular:487.96Ref: TM-T19965
5mg48,00€10mg75,00€25mg100,00€50mg133,00€100mg200,00€200mg295,00€1mL*10mM (DMSO)57,00€Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Fórmula:C30H35N7O2Pureza:99.99%Forma y color:SolidPeso molecular:525.64Ref: TM-T5462
1mg94,00€5mg187,00€10mg295,00€25mg497,00€50mg717,00€100mg982,00€500mg1.998,00€1mL*10mM (DMSO)235,00€G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Ref: TM-T8742
1mg35,00€5mg71,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€1mL*10mM (DMSO)78,00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Fórmula:C16H12N2O3Pureza:98.69%Forma y color:SolidPeso molecular:280.28Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Forma y color:SolidPeso molecular:557.04Osimertinib mesylate
CAS:Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.
Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:595.71RG13022
CAS:RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Fórmula:C16H14N2O2Pureza:98.38%Forma y color:SolidPeso molecular:266.29RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Forma y color:SolidPeso molecular:275.13Allitinib tosylate
CAS:Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.Fórmula:C31H26ClFN4O5SPureza:98.46% - 98.68%Forma y color:SolidPeso molecular:621.08(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Fórmula:C29H35ClFN7O3Pureza:99.64%Forma y color:SolidPeso molecular:584.08BI-4020
CAS:BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Fórmula:C30H38N8O2Pureza:97.21% - >99.99%Forma y color:SolidPeso molecular:542.68Ref: TM-T10534
1mg161,00€5mg376,00€10mg538,00€25mg803,00€50mg1.071,00€100mg1.431,00€200mg1.953,00€1mL*10mM (DMSO)447,00€Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:487.53Avitinib maleate
CAS:Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.Fórmula:C30H30FN7O6Pureza:98% - 99.74%Forma y color:SolidPeso molecular:603.61Alflutinib mesylate
CAS:Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Fórmula:C29H35F3N8O5SPureza:97.94% - 99.63%Forma y color:SolidPeso molecular:664.70(E)-AG 556
CAS:AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
Fórmula:C20H20N2O3Pureza:99.93%Forma y color:Light Yellow PowderPeso molecular:336.38NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Fórmula:C11H6N4O4SPureza:99.84%Forma y color:SolidPeso molecular:290.25Ref: TM-T6908
2mg34,00€5mg48,00€10mg63,00€25mg117,00€50mg178,00€100mg334,00€200mg469,00€1mL*10mM (DMSO)50,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Fórmula:C27H31N7O2Pureza:98.40% - 99.59%Forma y color:Solid PowderPeso molecular:485.58Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Forma y color:SolidPeso molecular:469.94Ref: TM-T2483
1mg35,00€2mg50,00€5mg74,00€10mg120,00€25mg170,00€50mg215,00€100mg334,00€200mg421,00€500mg692,00€1mL*10mM (DMSO)74,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Forma y color:Yellow SolidPeso molecular:282.38Poziotinib hydrochloride
CAS:Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.Fórmula:C23H22Cl3FN4O3Pureza:99.69% - 99.81%Forma y color:SolidPeso molecular:527.8PP 3
CAS:PP 3 is a Negative control for the Src kinase inhibitor PP 2Fórmula:C11H9N5Pureza:98.61%Forma y color:Whit To Off-White SolidPeso molecular:211.22Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Fórmula:C28H33N7O2Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:499.61Ref: TM-T2490
1g138,00€2g197,00€5g329,00€2mg34,00€5mg52,00€10mg55,00€25mg67,00€50mg80,00€100mg94,00€500mg114,00€1mL*10mM (DMSO)52,00€Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Fórmula:C26H28Cl2N6O2SForma y color:SolidPeso molecular:559.51Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Fórmula:C15H12O5Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:272.25Ref: TM-T6427
1mg40,00€2mg52,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)82,00€PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Fórmula:C14H12BrN5Pureza:98.81%Forma y color:SolidPeso molecular:330.18Ref: TM-T5410
1mg38,00€5mg80,00€10mg113,00€25mg205,00€50mg358,00€100mg523,00€200mg750,00€1mL*10mM (DMSO)93,00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C23H20N6OPureza:99.71%Forma y color:SolidPeso molecular:396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€1mL*10mM (DMSO)203,00€PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Fórmula:C16H15BrClN3O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:396.67EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Fórmula:C19H14FN3O3SPureza:98.00% - 99.12%Forma y color:SolidPeso molecular:383.4AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H31N7O2Pureza:97.07% - 99.75%Forma y color:SolidPeso molecular:485.58Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Fórmula:C270H401N73O83S7Pureza:97.17%Forma y color:SolidPeso molecular:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Fórmula:C14H18N2O5Pureza:99.68%Forma y color:White To Off-White SolidPeso molecular:294.3Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Fórmula:C10H6N2O2Pureza:99.7% - 99.86%Forma y color:Yellow-Tan SolidPeso molecular:186.17EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Fórmula:C22H23ClFN5O3Pureza:98.20% - 99.36%Forma y color:White To Off-White SolidPeso molecular:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Fórmula:C20H14Cl2FN5O2SPureza:97.6% - >99.99%Forma y color:SolidPeso molecular:478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)170,00€AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Fórmula:C19H18N2O3Pureza:98.02% - 99.94%Forma y color:SolidPeso molecular:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Fórmula:C16H15N3O2Pureza:99.66% - 99.92%Forma y color:SolidPeso molecular:281.31AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Fórmula:C16H14ClN3O2Pureza:99.03% - 99.71%Forma y color:SolidPeso molecular:315.75Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Forma y color:SolidPeso molecular:491.39EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Fórmula:C17H16BrN3O2Pureza:99.087% - 99.88%Forma y color:SolidPeso molecular:374.23Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.84%Forma y color:Off-White SolidPeso molecular:467.92WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Fórmula:C24H25ClN6O2Pureza:97.15%Forma y color:SolidPeso molecular:464.95Ref: TM-T6733
1mg50,00€2mg71,00€5mg92,00€10mg170,00€25mg301,00€50mg484,00€100mg692,00€1mL*10mM (DMSO)101,00€CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Fórmula:C17H16FN5Pureza:99.29%Forma y color:SolidPeso molecular:309.34CNX-2006
CAS:CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Fórmula:C26H27F4N7O2Pureza:98.85% - 99.16%Forma y color:SolidPeso molecular:545.53Sapitinib
CAS:Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFórmula:C23H25ClFN5O3Pureza:98.89% - 99.83%Forma y color:SolidPeso molecular:473.93Olmutinib
CAS:Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Fórmula:C26H26N6O2SPureza:99.14% - 99.63%Forma y color:SolidPeso molecular:486.59Ref: TM-T6918
2mg37,00€5mg54,00€10mg84,00€25mg130,00€50mg170,00€100mg268,00€200mg437,00€1mL*10mM (DMSO)56,00€Cyasterone
CAS:Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFórmula:C29H44O8Pureza:99.32% - 99.70%Forma y color:SolidPeso molecular:520.65Leptomycin B
CAS:Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.Fórmula:C33H48O6Pureza:97.10% - 99.04%Forma y color:White Crystalline SolidPeso molecular:540.73Ref: TM-T15735
1mg202,00€2mg341,00€5mg620,00€10mg882,00€25mg1.320,00€50mg1.776,00€100mg2.403,00€1mL*10mM (DMSO)283,00€Genistein
CAS:Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.Fórmula:C15H10O5Pureza:98.22% - 99.64%Forma y color:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecular:270.24Rostafuroxin
CAS:Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension.Fórmula:C23H34O4Pureza:98.24% - >99.99%Forma y color:SolidPeso molecular:374.51Almonertinib mesylate
CAS:Almonertinib mesylate: EGFR tyrosine kinase inhibitor, targets EGFR-mutant non-small cell lung cancer.Fórmula:C31H39N7O5SPureza:99.92%Forma y color:SolidPeso molecular:621.75Ref: TM-T9865
1mg52,00€5mg110,00€10mg177,00€25mg301,00€50mg425,00€100mg605,00€200mg797,00€1mL*10mM (DMSO)161,00€(Rac)-JBJ-04-125-02
CAS:(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.Fórmula:C29H26FN5O3SPureza:97.57%Forma y color:SolidPeso molecular:543.61Ref: TM-T8872
1mg100,00€5mg205,00€10mg334,00€25mg567,00€50mg807,00€100mg1.099,00€1mL*10mM (DMSO)249,00€Mobocertinib
CAS:Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agentFórmula:C32H39N7O4Pureza:99.47% - 99.97%Forma y color:SolidPeso molecular:585.7CUDC-101
CAS:CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.Fórmula:C24H26N4O4Pureza:95.76% - 99.17%Forma y color:SolidPeso molecular:434.49Afatinib
CAS:Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Forma y color:Off-White SolidPeso molecular:485.94Ref: TM-T21312
5mg34,00€10mg49,00€25mg81,00€50mg109,00€100mg137,00€200mg168,00€500mg284,00€1mL*10mM (DMSO)50,00€PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Fórmula:C16H14BrN3O2Pureza:98.47% - 99.29%Forma y color:SolidPeso molecular:360.21Nazartinib
CAS:Nazartinib (EGF816) (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (Fórmula:C26H31ClN6O2Pureza:98.63% - ≥95%Forma y color:Solid PowderPeso molecular:495.02Ref: TM-T3506
1mg37,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)87,00€PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Fórmula:C18H18Cl2N6OPureza:97.39%Forma y color:SolidPeso molecular:405.28Gefitinib hydrochloride
CAS:Obtustatin triacetate is an integrin derived from the venom of Vipera lebetina obtusa and is an α1β1 integrin and in vivo angiogenesis inhibitor.Fórmula:C22H25Cl2FN4O3Pureza:99.8%Forma y color:SolidPeso molecular:483.36Cavutilide
CAS:Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.Fórmula:C22H26FN3O3Pureza:99.82% - 99.85%Forma y color:SolidPeso molecular:399.458Canertinib dihydrochloride
CAS:Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic andFórmula:C24H27Cl3FN5O3Pureza:99.13% - >99.99%Forma y color:SolidPeso molecular:558.86Almonertinib hydrochloride
CAS:Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation.Fórmula:C30H36ClN7O2Pureza:98.01% - 98.12%Forma y color:SolidPeso molecular:562.1BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Fórmula:C19H24N6O2Pureza:99.08%Forma y color:SolidPeso molecular:368.43Naquotinib mesylate
CAS:Naquotinib mesylate (ASP8273 (mesylate)) is an orally available, mutant-selective and irreversible inhibitor of EGFR(iC50s of 8-33 nM and 230 nM for toward EGFRFórmula:C31H46N8O6SPureza:98%Forma y color:SolidPeso molecular:658.81Zalutumumab
CAS:Zalutumumab is a high-affinity fully human monoclonal antibody ,the extracellular domain of the EGFR squamous cell carcinoma of the head and neck (SCCHN).Pureza:95%Forma y color:LiquidPeso molecular:146.63 kDaElgemtumab
CAS:Elgemtumab (LJM716) is a fully humanised monoclonal antibody targeting HER3/ERBB3, acting as an antagonist to block HER3/Akt phosphorylation antitumour.Pureza:95%Forma y color:LiquidPeso molecular:144.15 kDaIzalontamab
CAS:Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.Pureza:95%+ - 95.3% (SDS-PAGE); 99.2% (SEC-HPLC)Forma y color:LiquidPeso molecular:197.21 kDaEGFR T790M/L858R-IN-8
CAS:EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.Fórmula:C16H11BrN2O3Forma y color:SolidPeso molecular:359.17Serclutamab
CAS:Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR).Pureza:98%Forma y color:LiquidBecotatug
CAS:Becotatug (JMT101) is a humanised monoclonal antibody targeting EGFR, antitumour when combined with Osimertinib for treating EGFR-mutated advanced NSCLC.Pureza:95% - 99.1% (SDS-PAGE); 98.1% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.52 kDaAnbenitamab
CAS:Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.Forma y color:LiquidFutuximab
CAS:Futuximab is a chimeric monoclonal antibody targeting EGFR, commonly used in combination with zatuximab to form Sym004.Pureza:95% - 97.5% (SDS-PAGE); 96.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.28 kDaPonezumab
CAS:Ponezumab (PF-04360365), a humanized IgG2 antibody, lowers Aβ in the CNS & boosts mice memory. Used in Alzheimer's research.Forma y color:LiquidImgatuzumab
CAS:Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.
Forma y color:LiquidPeso molecular:145.0 (kDa)EGFR vIII Protein, Human, Recombinant (hFc)
EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Forma y color:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)Ref: TM-TMPJ-00647
1mg2.535,00€5µg90,00€10µg130,00€20µg193,00€50µg381,00€100µg600,00€200µg947,00€500µg1.765,00€Fidasimtamab
CAS:Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.Pureza:95% - 98.0% (SDS-PAGE); 98.3% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.72 kDaTyrphostin AG 494
CAS:Fórmula:C16H12N2O3Pureza:>98.0%(HPLC)(N)Forma y color:Light yellow to Amber to Dark green powder to crystalPeso molecular:280.28IGF-1R modulator 1
CAS:IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.Fórmula:C22H17N3O4Forma y color:SolidPeso molecular:387.39ZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Fórmula:C22H19ClFN3O2Pureza:99.43%Forma y color:SolidPeso molecular:411.86Ref: TM-T1991
1mg34,00€5mg66,00€10mg96,00€25mg225,00€50mg369,00€100mg550,00€200mg780,00€1mL*10mM (DMSO)69,00€lavendustin A
CAS:lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.Fórmula:C21H19NO6Pureza:98%Forma y color:Off-White SolidPeso molecular:381.38Icotinib
CAS:Icotinib (Conmana) is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.Fórmula:C22H21N3O4Pureza:99.76% - 99.94%Forma y color:SolidPeso molecular:391.42Icotinib Hydrochloride
CAS:Icotinib Hydrochloride, an oral EGFR inhibitor (BPI-2009H), may halt cancer growth by blocking EGFR signaling.Fórmula:C22H22ClN3O4Pureza:99.89%Forma y color:SolidPeso molecular:427.88TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Fórmula:C26H25ClF3N5O3Pureza:99.73%Forma y color:SolidPeso molecular:547.96Ref: TM-T6039
1mg38,00€5mg80,00€10mg120,00€25mg216,00€50mg354,00€100mg512,00€200mg727,00€1mL*10mM (DMSO)96,00€BIBX 1382 Dihydrochloride
CAS:BIBX 1382 Dihydrochloride blocks Lassa/Ebola entry, aids in studying virus-host interactions, and hints at kinase targets for therapy.Fórmula:C18H21Cl3FN7Forma y color:SolidPeso molecular:460.76EGFR-IN-69
CAS:EGFR-IN-69: Potent EGFR inhibitor for NSCLC research; IC50: 4.3-25.6 nM against various EGFR mutations.Fórmula:C31H37Cl2N7O3SForma y color:SolidPeso molecular:658.64RG 14467
CAS:RG 14467 is an antagonist of epidermal growth factor-urogastrone.Fórmula:C14H14N2O3Forma y color:SolidPeso molecular:258.27EGFR-IN-54
CAS:EGFR-IN-54 (Compound 3c) is a potent inhibitor of EGFR (IC50: 1.623 μM) and is toxic to cancer cells.Fórmula:C17H14N4O4S3Forma y color:SolidPeso molecular:434.51EGFR-IN-21
CAS:EGFR-IN-21, a potent EGFR inhibitor, exhibits an IC50 of 0.38 nM, demonstrating significant antitumor activity.Fórmula:C36H44BrN10O2PForma y color:SolidPeso molecular:759.68EGFR/HER2-IN-3
CAS:EGFR/HER2-IN-3 (Compound ZINC21942954) is a dual EGFR and HER2 inhibitor.Fórmula:C26H23N5O3Forma y color:SolidPeso molecular:453.49Tarlox-TKI
CAS:Tarlox-TKI (Kinase inhibitor-1) is a pan-ErbB inhibitor, the active ingredient of Tarloxotinib, which has antitumor activity.Fórmula:C19H18BrClN6OPureza:97.03%Forma y color:SolidPeso molecular:461.74EGFR T790M/L858R-IN-5
CAS:EGFR T790M/L858R-IN-5 (example 52) functions as a potent EGFR T790M/L858R inhibitor, demonstrating a 92.9% inhibition rate at a concentration of 0.05 μM [1].Fórmula:C28H31N9OPeso molecular:509.61EGFR-IN-68
CAS:EGFR-IN-68, an EGFR inhibitor, has an IC50 of 0.33 μM and shows significant anticancer effects.Fórmula:C24H22N2OForma y color:SolidPeso molecular:354.44
