EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 572 productos de "EGFR"
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PP2
CAS:<p>PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.</p>Fórmula:C15H16ClN5Pureza:98% - 98.21%Forma y color:White SolidPeso molecular:301.77Tyrphostin AG30
CAS:<p>Tyrphostin AG30 (AG30) (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.</p>Fórmula:C10H7NO4Pureza:99.02%Forma y color:SolidPeso molecular:205.17PD-161570
CAS:<p>PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.</p>Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51Lazertinib
CAS:<p>Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.</p>Fórmula:C30H34N8O3Pureza:98.7% - 99.90%Forma y color:SolidPeso molecular:554.64Tyrphostin A1
CAS:<p>Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .</p>Fórmula:C11H8N2OPureza:98.32%Forma y color:SolidPeso molecular:184.19WZ4002
CAS:<p>WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.</p>Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97MAZ51
CAS:<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38Gefitinib-based PROTAC 3
CAS:<p>Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).</p>Fórmula:C47H57ClFN7O8SPureza:97.29% - 98.25%Forma y color:SolidPeso molecular:934.51Dacomitinib hydrate
CAS:<p>Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of</p>Fórmula:C24H27ClFN5O3Pureza:99.52%Forma y color:SolidPeso molecular:487.96Almonertinib
CAS:<p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>Fórmula:C30H35N7O2Pureza:99.99%Forma y color:SolidPeso molecular:525.64G5-7
CAS:<p>G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.</p>Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39AG-494
CAS:<p>AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.</p>Fórmula:C16H12N2O3Pureza:98.69%Forma y color:SolidPeso molecular:280.28Neratinib
CAS:<p>Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.</p>Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Forma y color:SolidPeso molecular:557.04Osimertinib mesylate
CAS:<p>Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:595.71RG13022
CAS:<p>RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).</p>Fórmula:C16H14N2O2Pureza:98.38%Forma y color:SolidPeso molecular:266.29RG14620
CAS:<p>RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Forma y color:SolidPeso molecular:275.13Allitinib tosylate
CAS:<p>Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.</p>Fórmula:C31H26ClFN4O5SPureza:98.46% - 98.68%Forma y color:SolidPeso molecular:621.08(S)-Sunvozertinib
CAS:<p>(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.</p>Fórmula:C29H35ClFN7O3Pureza:99.64%Forma y color:SolidPeso molecular:584.08BI-4020
CAS:<p>BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.</p>Fórmula:C30H38N8O2Pureza:97.21% - >99.99%Forma y color:SolidPeso molecular:542.68Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:487.53
