EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 581 productos de "EGFR"
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PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Fórmula:C26H35Cl2N7OPureza:99.92%Forma y color:SolidPeso molecular:532.51Ref: TM-T23127
1mg34,00€5mg96,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€1mL*10mM (DMSO)118,00€Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Fórmula:C30H34N8O3Pureza:98.7% - 99.90%Forma y color:SolidPeso molecular:554.64Ref: TM-T4485
1mg46,00€2mg59,00€5mg96,00€10mg130,00€25mg215,00€50mg309,00€100mg444,00€200mg655,00€1mL*10mM (DMSO)104,00€Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Fórmula:C11H8N2OPureza:98.32%Forma y color:SolidPeso molecular:184.19WZ4002
CAS:WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Fórmula:C25H27ClN6O3Pureza:97.51%Forma y color:SolidPeso molecular:494.97Ref: TM-T6238
2mg34,00€5mg49,00€10mg70,00€25mg111,00€50mg177,00€100mg313,00€200mg464,00€1mL*10mM (DMSO)50,00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Forma y color:SolidPeso molecular:314.38Gefitinib-based PROTAC 3
CAS:Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Fórmula:C47H57ClFN7O8SPureza:97.29% - 98.25%Forma y color:SolidPeso molecular:934.51Dacomitinib hydrate
CAS:Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFórmula:C24H27ClFN5O3Pureza:99.52%Forma y color:SolidPeso molecular:487.96Ref: TM-T19965
5mg48,00€10mg75,00€25mg100,00€50mg133,00€100mg200,00€200mg295,00€1mL*10mM (DMSO)57,00€Almonertinib
CAS:Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Fórmula:C30H35N7O2Pureza:99.99%Forma y color:SolidPeso molecular:525.64Ref: TM-T5462
1mg94,00€5mg187,00€10mg295,00€25mg497,00€50mg717,00€100mg982,00€500mg1.998,00€1mL*10mM (DMSO)235,00€G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Ref: TM-T8742
1mg35,00€5mg71,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€1mL*10mM (DMSO)78,00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Fórmula:C16H12N2O3Pureza:98.69%Forma y color:SolidPeso molecular:280.28Neratinib
CAS:Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Fórmula:C30H29ClN6O3Pureza:96.17% - 99.85%Forma y color:SolidPeso molecular:557.04Osimertinib mesylate
CAS:Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor. Osimertinib mesylate has antitumor activity. Cost-effective and quality-assured.
Fórmula:C29H37N7O5SPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:595.71RG13022
CAS:RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).Fórmula:C16H14N2O2Pureza:98.38%Forma y color:SolidPeso molecular:266.29RG14620
CAS:RG14620 (Tyrphostin RG14620) is an epidermal growth factor receptor (EGFR) inhibitor.Fórmula:C14H8Cl2N2Pureza:99.82% - 99.87%Forma y color:SolidPeso molecular:275.13Allitinib tosylate
CAS:Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.Fórmula:C31H26ClFN4O5SPureza:98.46% - 98.68%Forma y color:SolidPeso molecular:621.08(S)-Sunvozertinib
CAS:(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.Fórmula:C29H35ClFN7O3Pureza:99.64%Forma y color:SolidPeso molecular:584.08BI-4020
CAS:BI-4020 is a fourth-generation, orally active, and non-covalent inhibitor of EGFR tyrosine kinase.Fórmula:C30H38N8O2Pureza:97.21% - >99.99%Forma y color:SolidPeso molecular:542.68Ref: TM-T10534
1mg161,00€5mg376,00€10mg538,00€25mg803,00€50mg1.071,00€100mg1.431,00€200mg1.953,00€1mL*10mM (DMSO)447,00€Avitinib
CAS:Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:487.53Avitinib maleate
CAS:Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.Fórmula:C30H30FN7O6Pureza:98% - 99.74%Forma y color:SolidPeso molecular:603.61Alflutinib mesylate
CAS:Alflutinib mesylate (AST2818 mesylate) ,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.Fórmula:C29H35F3N8O5SPureza:97.94% - 99.63%Forma y color:SolidPeso molecular:664.70(E)-AG 556
CAS:AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
Fórmula:C20H20N2O3Pureza:99.93%Forma y color:Light Yellow PowderPeso molecular:336.38NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Fórmula:C11H6N4O4SPureza:99.84%Forma y color:SolidPeso molecular:290.25Ref: TM-T6908
2mg34,00€5mg48,00€10mg63,00€25mg117,00€50mg178,00€100mg334,00€200mg469,00€1mL*10mM (DMSO)50,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:718.08AZ-5104
CAS:AZ5104 is a potent EGFR inhibitor.Fórmula:C27H31N7O2Pureza:98.40% - 99.59%Forma y color:Solid PowderPeso molecular:485.58Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Forma y color:SolidPeso molecular:469.94Ref: TM-T2483
1mg35,00€2mg50,00€5mg74,00€10mg120,00€25mg170,00€50mg215,00€100mg334,00€200mg421,00€500mg692,00€1mL*10mM (DMSO)74,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Forma y color:Yellow SolidPeso molecular:282.38Poziotinib hydrochloride
CAS:Oral poziotinib HCl targets EGFR/HER mutants, inhibiting cancer cell growth.Fórmula:C23H22Cl3FN4O3Pureza:99.69% - 99.81%Forma y color:SolidPeso molecular:527.8PP 3
CAS:PP 3 is a Negative control for the Src kinase inhibitor PP 2Fórmula:C11H9N5Pureza:98.61%Forma y color:Whit To Off-White SolidPeso molecular:211.22Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Fórmula:C28H33N7O2Pureza:99.32% - >99.99%Forma y color:SolidPeso molecular:499.61Ref: TM-T2490
1g138,00€2g197,00€5g329,00€2mg34,00€5mg52,00€10mg55,00€25mg67,00€50mg80,00€100mg94,00€500mg114,00€1mL*10mM (DMSO)52,00€Olmutinib hydrochloride
CAS:Olmutinib is a third-gen EGFR inhibitor for T790M-positive lung cancer, blocking phosphorylation and tumor pathways. Approved in Korea (2016).Fórmula:C26H28Cl2N6O2SForma y color:SolidPeso molecular:559.51Butein
CAS:Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Fórmula:C15H12O5Pureza:98.76% - >99.99%Forma y color:SolidPeso molecular:272.25Ref: TM-T6427
1mg40,00€2mg52,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)82,00€PD158780
CAS:PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Fórmula:C14H12BrN5Pureza:98.81%Forma y color:SolidPeso molecular:330.18Ref: TM-T5410
1mg38,00€5mg80,00€10mg113,00€25mg205,00€50mg358,00€100mg523,00€200mg750,00€1mL*10mM (DMSO)93,00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C23H20N6OPureza:99.71%Forma y color:SolidPeso molecular:396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€1mL*10mM (DMSO)203,00€PD153035 hydrochloride
CAS:PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Fórmula:C16H15BrClN3O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:396.67EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Fórmula:C19H14FN3O3SPureza:98.00% - 99.12%Forma y color:SolidPeso molecular:383.4AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H31N7O2Pureza:97.07% - 99.75%Forma y color:SolidPeso molecular:485.58Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Fórmula:C270H401N73O83S7Pureza:97.17%Forma y color:SolidPeso molecular:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Fórmula:C14H18N2O5Pureza:99.68%Forma y color:White To Off-White SolidPeso molecular:294.3Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Fórmula:C10H6N2O2Pureza:99.7% - 99.86%Forma y color:Yellow-Tan SolidPeso molecular:186.17EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4Ref: TM-T5168
1mg82,00€5mg159,00€10mg259,00€25mg520,00€50mg740,00€100mg1.008,00€500mg2.015,00€1mL*10mM (DMSO)168,00€Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Fórmula:C22H23ClFN5O3Pureza:98.20% - 99.36%Forma y color:White To Off-White SolidPeso molecular:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Fórmula:C20H14Cl2FN5O2SPureza:97.6% - >99.99%Forma y color:SolidPeso molecular:478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)170,00€AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Fórmula:C19H18N2O3Pureza:98.02% - 99.94%Forma y color:SolidPeso molecular:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Fórmula:C16H15N3O2Pureza:99.66% - 99.92%Forma y color:SolidPeso molecular:281.31AG-1478
CAS:AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Fórmula:C16H14ClN3O2Pureza:99.03% - 99.71%Forma y color:SolidPeso molecular:315.75Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Forma y color:SolidPeso molecular:491.39EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Fórmula:C17H16BrN3O2Pureza:99.087% - 99.88%Forma y color:SolidPeso molecular:374.23Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.84%Forma y color:Off-White SolidPeso molecular:467.92WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Fórmula:C24H25ClN6O2Pureza:97.15%Forma y color:SolidPeso molecular:464.95Ref: TM-T6733
1mg50,00€2mg71,00€5mg92,00€10mg170,00€25mg301,00€50mg484,00€100mg692,00€1mL*10mM (DMSO)101,00€
