EGFR
Los inhibidores del receptor del factor de crecimiento epidérmico (EGFR) son compuestos que bloquean la señalización del EGFR, un receptor que a menudo está sobreexpresado en varios tipos de cáncer y que juega un papel crucial en la angiogénesis. Los inhibidores del EGFR se utilizan para prevenir el crecimiento tumoral y las metástasis al interrumpir las vías que promueven la formación de vasos sanguíneos en los tumores. Estos inhibidores son ampliamente utilizados en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia selección de inhibidores de EGFR de alta calidad para apoyar su investigación en oncología y angiogénesis.
Se han encontrado 593 productos de "EGFR"
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β-Hydroxyisovalerylshikonin
CAS:<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Fórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C23H20N6OPureza:99.71%Forma y color:SolidPeso molecular:396.44PD153035 hydrochloride
CAS:<p>PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.</p>Fórmula:C16H15BrClN3O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:396.67EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Fórmula:C19H14FN3O3SPureza:98.00% - 99.12%Forma y color:SolidPeso molecular:383.4AZ7550
CAS:AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H31N7O2Pureza:97.07% - 99.75%Forma y color:SolidPeso molecular:485.58Epidermal Growth Factor
CAS:EGF binds EGFR, promotes cell growth & heals diabetic foot ulcers.Fórmula:C270H401N73O83S7Pureza:97.17%Forma y color:SolidPeso molecular:6222CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Fórmula:C14H18N2O5Pureza:99.68%Forma y color:White To Off-White SolidPeso molecular:294.3Tyrphostin 23
CAS:Tyrphostin 23 (AG18) inhibits EGFR with IC50 of 35 μM.Fórmula:C10H6N2O2Pureza:99.7% - 99.86%Forma y color:Yellow-Tan SolidPeso molecular:186.17EGFR-IN-12
CAS:EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Forma y color:SolidPeso molecular:413.4Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Fórmula:C22H23ClFN5O3Pureza:98.20% - 99.36%Forma y color:White To Off-White SolidPeso molecular:459.9MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Fórmula:C20H14Cl2FN5O2SPureza:97.6% - >99.99%Forma y color:SolidPeso molecular:478.33Desmethyl Erlotinib hydrochloride
CAS:<p>Desmethyl Erlotinib hydrochloride (OSI 420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor.</p>Fórmula:C21H21N3O4·HClPureza:99.49%Forma y color:SolidPeso molecular:415.87AG 555
CAS:AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Fórmula:C19H18N2O3Pureza:98.02% - 99.94%Forma y color:SolidPeso molecular:322.36WHI-P258
CAS:WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Fórmula:C16H15N3O2Pureza:99.66% - 99.92%Forma y color:SolidPeso molecular:281.31AG-1478
CAS:<p>AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.</p>Fórmula:C16H14ClN3O2Pureza:99.03% - 99.71%Forma y color:SolidPeso molecular:315.75Tesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 98.66%Forma y color:SolidPeso molecular:491.39EBE-A22
CAS:EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Fórmula:C17H16BrN3O2Pureza:99.087% - 99.88%Forma y color:SolidPeso molecular:374.23Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.84%Forma y color:Off-White SolidPeso molecular:467.92WZ-3146
CAS:WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Fórmula:C24H25ClN6O2Pureza:97.15%Forma y color:SolidPeso molecular:464.95CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Fórmula:C17H16FN5Pureza:99.29%Forma y color:SolidPeso molecular:309.34
