BTK
Los inhibidores de la tirosina quinasa de Bruton (BTK) son compuestos que específicamente se dirigen e inhiben la BTK, una enzima crucial involucrada en la señalización del receptor de células B y en la regulación de la angiogénesis. La BTK desempeña un papel significativo en la proliferación y supervivencia de las células cancerosas, particularmente en las malignidades hematológicas. Al inhibir la BTK, estos compuestos pueden interrumpir la angiogénesis y el crecimiento tumoral, lo que los convierte en valiosos en la terapia contra el cáncer. En CymitQuimica, ofrecemos una gama de inhibidores de BTK de alta calidad para apoyar su investigación en oncología, inmunología y angiogénesis.
Se han encontrado 146 productos de "BTK"
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BMS-986142
CAS:<p>BMS-986142 is a potent and highly selective reversible BTK inhibitor (IC50: 0.5 nM).</p>Fórmula:C32H30F2N4O4Pureza:98.7% - 99.76%Forma y color:SolidPeso molecular:572.6Acalabrutinib
CAS:<p>Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.</p>Fórmula:C26H23N7O2Pureza:98.94% - 99.64%Forma y color:SolidPeso molecular:465.51(Rac)-IBT6A
CAS:<p>(Rac)-IBT6A is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib and can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>Fórmula:C22H22N6OPureza:99.24%Forma y color:SolidPeso molecular:386.45TL-895
CAS:<p>TL-895 is a potent, selective ATP-competitive BTK inhibitor (IC50 = 1.5 nM, Ki = 11.9 nM).</p>Fórmula:C25H26FN5O2Pureza:99.96%Forma y color:SolidPeso molecular:447.5Spebrutinib
CAS:<p>Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic</p>Fórmula:C22H22FN5O3Pureza:97.02% - >99.99%Forma y color:SolidPeso molecular:423.44ONO-4059 analog
CAS:<p>ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.</p>Fórmula:C25H24N6O3Pureza:99.25%Forma y color:SolidPeso molecular:456.5RN486
CAS:<p>RN486 is an effective and specific BTK inhibitor (IC50: 4 nM).</p>Fórmula:C35H35FN6O3Pureza:99.38%Forma y color:SolidPeso molecular:606.69Branebrutinib
CAS:<p>Branebrutinib (BMS986195) is a potent, covalent inhibitor of Bruton's tyrosine kinase (BTK), >5,000-fold selective over all kinases outside of the Tec family.</p>Fórmula:C20H23FN4O2Pureza:95.86% - 99.31%Forma y color:SolidPeso molecular:370.42Larotinib mesylate hydrate
CAS:<p>Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nM</p>Fórmula:C26H36ClFN4O11S2Forma y color:SolidPeso molecular:699.17CNX-774
CAS:<p>CNX-774 is a highly specific, irreversible, and orally active BTK inhibitor (IC50<1 nM).</p>Fórmula:C26H22FN7O3Pureza:97.35% - 99.11%Forma y color:SolidPeso molecular:499.5CGI-1746
CAS:<p>CGI1746 is a potent and highly selective small-molecule Btk inhibitor with IC50 of 1.9 nM.</p>Fórmula:C34H37N5O4Pureza:97.69% - 97.88%Forma y color:SolidPeso molecular:579.69Avitinib
CAS:<p>Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor,</p>Fórmula:C26H26FN7O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:487.53BTK IN-1
CAS:<p>BTK IN-1 (SNS062 analog) (SNS062 analog) is an effective BTK inhibitor (IC50: <100 nM).</p>Fórmula:C19H21ClN6OPureza:97.38%Forma y color:SolidPeso molecular:384.86BTK Protein, Human, Recombinant (His)
<p>Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.</p>Pureza:90%Forma y color:Lyophilized PowderPeso molecular:78.3 kDa (predicted)Ibrutinib-d5
CAS:<p>Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.</p>Fórmula:C25H24N6O2Pureza:98%Forma y color:SolidPeso molecular:445.53SJF620
CAS:<p>SJF620 is a potent degrader of PROTAC BTK(DC50 : 7.9 nM).</p>Fórmula:C41H44N8O7Pureza:98%Forma y color:SolidPeso molecular:760.84JAK3/BTK-IN-5
CAS:<p>JAK3/BTK-IN-5 is a potent dual inhibitor targeting JAK3 and BTK with synergistic effects, valuable for related autoimmune disease research.</p>Fórmula:C19H22ClN7O2Forma y color:SolidPeso molecular:415.88JS25
CAS:<p>JS25, a selective BTK inhibitor, inactivates it with a 5.8 nM IC50, halts cancer cell growth, induces death, and aids against lymphoma.</p>Fórmula:C29H24N4O4SForma y color:SolidPeso molecular:524.59BLK-IN-2
CAS:<p>BLK-IN-2为一种高效、选择性且不可逆的B-淋巴酪氨酸激酶(BLK)抑制剂，具有5.9 nM的IC50值。该化合物亦能抑制BTK，其IC50值为202.0 nM。BLK-IN-2在多种淋巴瘤细胞中展现出显著的抗增殖作用。</p>Fórmula:C39H41N9O3Forma y color:SolidPeso molecular:683.8GDC-0834 Racemate
CAS:<p>GDC-0834 Racemate is the racemate form of GDC-0834, which is an effective and selective BTK inhibitor</p>Fórmula:C33H36N6O3SForma y color:SolidPeso molecular:596.74
