Syk
Los inhibidores de Syk (tirosina quinasa del bazo) son compuestos que se dirigen a Syk, una quinasa involucrada en la señalización de células inmunitarias y la regulación de la angiogénesis. Syk desempeña un papel en las respuestas inflamatorias que pueden contribuir a la angiogénesis tumoral. Inhibir Syk puede reducir la formación de vasos sanguíneos inducida por la inflamación en los tumores, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer y la investigación sobre inflamación. En CymitQuimica, ofrecemos una amplia gama de inhibidores de Syk de alta calidad para apoyar su investigación en inmunología, oncología y angiogénesis.
Se han encontrado 37 productos de "Syk"
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Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Forma y color:SolidPeso molecular:445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€1mL*10mM (DMSO)81,00€MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Forma y color:SolidPeso molecular:312.3Ref: TM-T3185
1mg39,00€2mg51,00€5mg84,00€10mg124,00€25mg219,00€50mg329,00€100mg487,00€500mg1.026,00€1mL*10mM (DMSO)92,00€Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Forma y color:SolidPeso molecular:624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€1mL*10mM (DMSO)110,00€Entospletinib
CAS:Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Fórmula:C23H21N7OPureza:98.54% - 99.74%Forma y color:SolidPeso molecular:411.46Ref: TM-T6101
1mg38,00€2mg49,00€5mg81,00€10mg97,00€25mg170,00€50mg259,00€100mg416,00€200mg617,00€1mL*10mM (DMSO)88,00€R406
CAS:R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Forma y color:SolidPeso molecular:628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€1mL*10mM (DMSO)120,00€R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Forma y color:SolidPeso molecular:470.45Ref: TM-T2467
1mg47,00€5mg70,00€10mg97,00€25mg187,00€50mg338,00€100mg535,00€500mg1.121,00€1mL*10mM (DMSO)72,00€Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.85%Forma y color:SolidPeso molecular:482Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Fórmula:C14H15F3N6OPureza:97.63%Forma y color:SolidPeso molecular:340.3ER-27319
CAS:ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFórmula:C20H22N2O5Pureza:98%Forma y color:SolidPeso molecular:370.4Sovleplenib
CAS:Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Fórmula:C24H30N6O3SPureza:99.71%Forma y color:SolidPeso molecular:482.6Ref: TM-T32088
1mg127,00€5mg305,00€10mg459,00€25mg777,00€50mg1.216,00€100mg1.890,00€200mg2.547,00€1mL*10mM (DMSO)324,00€RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Fórmula:C18H25N7OPureza:99.90%Forma y color:SolidPeso molecular:355.44Syk-IN-3
CAS:Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.
Fórmula:C24H28N4O3SPureza:97.29% - >99.99%Forma y color:SolidPeso molecular:452.57OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Fórmula:C18H15N3O3SPureza:98%Forma y color:Dark Orange SolidPeso molecular:353.39Lanraplenib monosuccinate
CAS:Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Fórmula:C27H31N9O5Pureza:98%Forma y color:SolidPeso molecular:561.59MK-8457
CAS:MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Fórmula:C24H25F3N4O3SForma y color:SolidPeso molecular:506.54Syk-IN-8
CAS:Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.
Fórmula:C23H26N10Pureza:98%Forma y color:SolidPeso molecular:442.52
