Caspasa
Los inhibidores de caspasas son compuestos que bloquean la actividad de las caspasas, una familia de proteasas que son ejecutores centrales de la apoptosis. Las caspasas escinden sustratos específicos dentro de la célula para desencadenar el proceso apoptótico, lo que conduce a la muerte celular programada. Los inhibidores de caspasas se utilizan para estudiar los mecanismos de la apoptosis, así como para prevenir la muerte celular no deseada en varios modelos de investigación. Estos inhibidores también se exploran en contextos terapéuticos para proteger las células de la apoptosis en enfermedades como la neurodegeneración. En CymitQuimica, ofrecemos una amplia gama de inhibidores de caspasas de alta calidad para apoyar su investigación en apoptosis, muerte celular y campos relacionados.
Se han encontrado 163 productos para "Caspasa".
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Roxatidine
CAS:Roxatidine, a metabolite of Roxatidine acetate, is a H2-receptor antagonist that prevents ulcers and has anti-inflammatory properties.Fórmula:C17H26N2O3Forma y color:SolidPeso molecular:306.4Protease Inhibitor Library
A unique collection of xnum protease and proteasome inhibitors for research in chemical genomics, and drug screening;Forma y color:Odour SolidRef: TM-L1100
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarBiotin-DEVD-CHO TFA
Biotin-DEVD-CHO (TFA) is the biotin-conjugated form of the caspase-3 and caspase-7 inhibitor Ac-DEVD-CHO. It can be utilized for affinity purification of active caspase-3, -6, -7, and -8 and is also applicable for in vitro detection of active caspase-3.Forma y color:Odour SolidPerfluorodecanoic acid
CAS:Perfluorodecanoic acid is a biochemical.Fórmula:C10HF19O2Forma y color:SolidPeso molecular:514.08Ac-AAVALLPAVLLALLAP-LEVD-CHO
CAS:Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1].Fórmula:C96H164N20O25Pureza:98%Forma y color:SolidPeso molecular:1998.45Ac-AAVALLPAVLLALLAPVAD-CHO TFA
Ac-AAVALLPAVLLALLAPVAD-CHO (TFA) is a complex of Ac-VAD-CHO. It acts as a non-selective caspase inhibitor and features a hydrophobic sequence derived from K-FGF that enables cell penetration.VCP/p97 IN-3
VCP/p97 IN-3 is an allosteric inhibitor of VCP/p97. It exhibits inhibitory activity against VCP, with an IC50 of 9 nM, and shows IC50 values of 12 nM (N660K) and 19 nM (V474A/D649A) for mutant VCP proteins. VCP/p97 IN-3 increases the levels of K48 ubiquitination and caspase-3. It activates endoplasmic reticulum stress and the unfolded protein response (UPR). In a subcutaneous xenograft mouse model with RPMI-8226 cells, VCP/p97 IN-3 suppresses tumor growth. This compound is applicable for research in multiple myeloma.Forma y color:Odour SolidBOC-D-FMK
CAS:Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).Fórmula:C11H18FNO5Pureza:97.02%Forma y color:SolidPeso molecular:263.26Ref: TM-T10580
1mg50,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg167,00€25mg326,00€50mg462,00€100mg640,00€200mg884,00€TNF-α-IN-11
TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor exhibiting a dissociation constant (K D) of 12.06 μM.Fórmula:C24H26N2O5Forma y color:SolidPeso molecular:422.47PQ401
CAS:PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).Fórmula:C18H16ClN3O2Pureza:99.77%Forma y color:SolidPeso molecular:341.79Ac-LEHD-AMC
CAS:Ac-LEHD-AMC, a fluorogenic caspase-9 substrate, releases fluorescent AMC upon cleavage, aiding caspase-9 activity measurement.Fórmula:C33H41N7O11Forma y color:SolidPeso molecular:711.729Ac-VDVAD-CHO TFA
Ac-VDVAD-CHO (TFA) is a caspase-2/3 inhibitor with IC50 values of 46 nM and 15 nM, respectively.Forma y color:Odour SolidDiethylnorspermine HCl
CAS:Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) potently induces SSAT (spermidine/spermine N1-acetyltransferase) mRNA and effectivelyFórmula:C13H36Cl4N4Pureza:99.79% - 99.86%Forma y color:SolidPeso molecular:390.26Pralnacasan
CAS:Pralnacasan blocks IL-18, IL-1β, IFN-γ. It’s a potent oral enzyme inhibitor with use in arthritis therapy (Ki: 1.4 nM).Fórmula:C26H29N5O7Pureza:98%Forma y color:SolidPeso molecular:523.54Ac-IEPD-AFC
CAS:Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.Fórmula:C32H38F3N5O11Pureza:99.16%Forma y color:White SolidPeso molecular:725.67Ac-LEVD-CHO
CAS:Ac-LEVD-CHO, a caspase-4 inhibitor, is a peptide with the sequence Ac-Leu-Glu-Val-Asp-al [1].Fórmula:C22H36N4O9Forma y color:SolidPeso molecular:500.54Z-VDVA-(DL-Asp)-FMK
CAS:Z-VDVA-(DL-Asp)-FMK is a derivative compound of Z-VDVAD-FMK specifically designed as an inhibitor targeting caspase-2.Fórmula:C32H46FN5O11Forma y color:SolidPeso molecular:695.742Boc-Asp(OBzl)-CMK
CAS:Boc-Asp(OBzl)-CMK, an inhibitor of IL-1 converting enzyme (ICE, caspase1), prevents the death of CHP100 neuroblastoma cells and inhibits IL-1β release induced by the viral coat protein [1].Fórmula:C17H22ClNO5Forma y color:SolidPeso molecular:355.81Z-WEHD-FMK
CAS:Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).Fórmula:C37H42FN7O10Pureza:98%Forma y color:SolidPeso molecular:763.78IRF1-IN-2
CAS:IRF1-IN-2 is a small molecule IRF1 inhibitor that suppresses pyroptosis, protecting against radiation-induced skin damage.Fórmula:C18H20N2O4SPureza:99.85%Forma y color:SolidPeso molecular:360.43
