IAP
Los inhibidores de las proteínas inhibidoras de la apoptosis (IAP) son compuestos que bloquean la actividad de las IAP, una familia de proteínas que previenen la apoptosis al inhibir caspasas y otros componentes de la maquinaria apoptótica. Los inhibidores de IAP promueven la apoptosis en células cancerosas al neutralizar estas señales de supervivencia, lo que los convierte en herramientas importantes en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia gama de inhibidores de IAP de alta calidad para apoyar su investigación en oncología, apoptosis y desarrollo terapéutico.
Se han encontrado 71 productos para "IAP".
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MV1
CAS:MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Fórmula:C33H44N4O5Pureza:99.86%Forma y color:SolidPeso molecular:576.73Ref: TM-T16163
2mg44,00€5mg67,00€1mL*10mM (DMSO)86,00€10mg112,00€25mg187,00€50mg280,00€100mg396,00€200mg522,00€XIAP BIR2/BIR2-3 inhibitor-2
CAS:XIAP BIR2/BIR2-3 Inhibitor-2 is a dual inhibitor of BIR2 and BIR2-3 with IC50 values less than 1 nM. It can be used in the study of cancers [1].Fórmula:C80H96N20O12Peso molecular:1529.75S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Fórmula:C52H75Cl2FN6O6SForma y color:SolidPeso molecular:1000.48299XIAP BIR2/BIR2-3 inhibitor-3
CAS:XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Fórmula:C86H106N18O16S2Forma y color:SolidPeso molecular:1712XIAP BIR2/BIR2-3 inhibitor-1
CAS:XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].Fórmula:C72H96N16O14Forma y color:SolidPeso molecular:1409.63SBP-0636457
CAS:SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Fórmula:C25H36N4O4Forma y color:SolidPeso molecular:456.587SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Fórmula:C62H85ClN14O6Pureza:98%Forma y color:SolidPeso molecular:1157.88Dasminapant
CAS:APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.Fórmula:C60H72N10O10S2Forma y color:White SolidPeso molecular:1157.41PROTAC KRAS G12C degrader-2
CAS:PROTAC KRAS G12C degrader-2 (compound 432) is a targeted modulator of K-Ras protein hydrolysis that functions as a bifunctional PROTAC molecule, incorporating a cereblon inhibitor of apoptosis proteins (IAP) ligand on one terminus and a KRAS-binding moiety on the opposite end, thereby enabling selective recruitment of mutant KRAS G12C to the ubiquitin–proteasome system for controlled degradation and mechanistic investigation of KRAS-driven oncogenic signaling pathways.Fórmula:C51H53ClFN9O7Forma y color:SolidPeso molecular:958.47MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potentialForma y color:Odour SolidCST626
CAS:CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.Fórmula:C61H82N8O9SPureza:95.87%Forma y color:SolidPeso molecular:1103.42Anti-CD47 Antibody (4E249)
Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.Forma y color:Odour LiquidAnti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Forma y color:Odour LiquidAnti-CD47 Antibody (5K435)
Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.Forma y color:Odour LiquidCD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Forma y color:Lyophilized PowderPeso molecular:39.9 kDa (predicted)Anti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Forma y color:Odour LiquidAnti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Forma y color:Odour LiquidAnti-CD47 Antibody-FITC (9X161)
Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.Forma y color:Odour LiquidAnti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Forma y color:Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Forma y color:Odour LiquidAnti-CD47 Antibody (5E321)
Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.Forma y color:Odour LiquidAnti-CD47 Antibody (1F304)
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.Forma y color:Odour LiquidAnti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Forma y color:Odour LiquidAnti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Forma y color:Odour LiquidAnti-CD47 Antibody (8K78)
Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.Forma y color:Odour LiquidAZD5582
CAS:AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Fórmula:C58H78N8O8Pureza:98.75% - >99.99%Forma y color:SolidPeso molecular:1015.29CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Forma y color:Lyophilized PowderPeso molecular:15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and isPureza:92.7%Forma y color:Lyophilized PowderPeso molecular:54.1 kDa (predicted); 66 kDa (reducing conditions)Ref: TM-TMPY-00570
5µg78,00€10µg110,00€20µg177,00€50µg348,00€100µg613,00€200µg1.080,00€500µg2.277,00€CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.Forma y color:White Lyophilized PowderPeso molecular:30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Pureza:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCForma y color:White Lyophilized PowderPeso molecular:40.5 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-03883
5µg50,00€10µg80,00€20µg114,00€50µg219,00€100µg421,00€200µg622,00€500µg1.324,00€1mg2.673,00€CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Forma y color:Lyophilized PowderPeso molecular:48-65 KDa (reducing condition)Ref: TM-TMPJ-00212
5µg56,00€10µg88,00€20µg118,00€50µg200,00€100µg358,00€200µg643,00€500µg1.414,00€1mg2.457,00€CD47 Protein, Human, Recombinant (aa 19-139, His)
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:14.5 kDa (predicted); 40-55 kDa (reducing conditions)Ref: TM-TMPY-06367
5µg77,00€10µg112,00€20µg177,00€50µg351,00€100µg680,00€200µg1.018,00€500µg2.152,00€1mg4.393,00€Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalForma y color:Lyophilized PowderPeso molecular:54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalForma y color:Lyophilized PowderPeso molecular:53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Forma y color:Lyophilized PowderPeso molecular:17.1 kDa (predicted); 38.8 kDa (reducing conditions)Alkaline phosphatase/ALPI Protein, Human, Recombinant (hFc)
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Forma y color:Lyophilized PowderPeso molecular:15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Pureza:Greater than 95% as determined by reducing SDS-PAGE. - SDS-PAGE: 100%; SEC-HPLC: 97%Forma y color:White Lyophilized PowderPeso molecular:30-45 KDa (reducing condition)CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.Pureza:97.6%Forma y color:Lyophilized PowderPeso molecular:14.5 kDa (predicted)CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Forma y color:Lyophilized PowderPeso molecular:13.8 kDa (predicted)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Forma y color:Lyophilized PowderPeso molecular:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:White Lyophilized PowderPeso molecular:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Pureza:97.8%Forma y color:Lyophilized PowderPeso molecular:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.4%Forma y color:White Lyophilized PowderPeso molecular:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-02650
5µg78,00€10µg110,00€20µg177,00€50µg348,00€100µg595,00€200µg1.009,00€500µg2.043,00€ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Forma y color:White SolidPeso molecular:539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFórmula:C57H92O27Pureza:98.95% - ≥98%Forma y color:SolidPeso molecular:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Forma y color:SolidPeso molecular:498.64Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Forma y color:SolidPeso molecular:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€4-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Fórmula:C8H8O3Pureza:99.64%Forma y color:White SolidPeso molecular:152.15SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Forma y color:SolidPeso molecular:1121.42
