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Survivin

Survivin

Los inhibidores de survivina se dirigen a la proteína survivina, un miembro de la familia de inhibidores de la apoptosis (IAP) que se expresa en altos niveles en las células cancerosas y las ayuda a evadir la apoptosis. Survivina juega un papel clave en la regulación del ciclo celular y la inhibición de la apoptosis, lo que la convierte en un objetivo crítico en la terapia contra el cáncer. Al inhibir la survivina, estos compuestos pueden promover la apoptosis en las células cancerosas, ofreciendo potenciales beneficios terapéuticos. En CymitQuimica, ofrecemos una selección de inhibidores de survivina de alta calidad para apoyar su investigación en oncología, apoptosis y desarrollo terapéutico.

Se han encontrado 14 productos de "Survivin"

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  • MNK8 

    CAS:
    MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.
    Fórmula:C15H12N2O2
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:252.27
  • ZLDI-8

    CAS:
    <p>ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.</p>
    Fórmula:C24H23N3O3S
    Pureza:98.09%
    Forma y color:Solid
    Peso molecular:433.52
  • MX106-4C


    <p>MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.</p>
    Fórmula:C23H25BrN2O2
    Peso molecular:440.10994
  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)


    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Forma y color:Lyophilized Powder
    Peso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.
  • NSC 80467

    CAS:
    NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.
    Fórmula:C24H22BrN3O5
    Pureza:99.25%
    Forma y color:Solid
    Peso molecular:512.35
  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated


    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Forma y color:Lyophilized Powder
    Peso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.
  • HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)


    Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.
    Forma y color:Lyophilized Powder
    Peso molecular:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
  • LQZ-7I

    CAS:
    LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors
    Fórmula:C20H14F2N4
    Pureza:99.81% - 99.87%
    Forma y color:Solid
    Peso molecular:348.35
  • Cucurbitacin IIA

    CAS:
    1.
    Fórmula:C32H50O8
    Pureza:98.62% - 99.87%
    Forma y color:Solid
    Peso molecular:562.73
  • Isolinderalactone

    CAS:
    Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
    Fórmula:C15H16O3
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:244.29
  • 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea

    CAS:
    <p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>
    Fórmula:C21H13ClF3N3O2
    Pureza:99.41%
    Forma y color:Solid
    Peso molecular:431.8
  • Sepantronium bromide

    CAS:
    <p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>
    Fórmula:C20H19BrN4O3
    Pureza:99.68% - 99.85%
    Forma y color:Solid
    Peso molecular:443.26
  • GDP366

    CAS:
    <p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>
    Fórmula:C20H17N5OS
    Pureza:98.78% - 99.84%
    Forma y color:Solid
    Peso molecular:375.45
  • AQIM-I

    CAS:
    <p>AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].</p>
    Fórmula:C17H13IN2O2
    Forma y color:Solid
    Peso molecular:404.20