Survivin
Los inhibidores de survivina se dirigen a la proteína survivina, un miembro de la familia de inhibidores de la apoptosis (IAP) que se expresa en altos niveles en las células cancerosas y las ayuda a evadir la apoptosis. Survivina juega un papel clave en la regulación del ciclo celular y la inhibición de la apoptosis, lo que la convierte en un objetivo crítico en la terapia contra el cáncer. Al inhibir la survivina, estos compuestos pueden promover la apoptosis en las células cancerosas, ofreciendo potenciales beneficios terapéuticos. En CymitQuimica, ofrecemos una selección de inhibidores de survivina de alta calidad para apoyar su investigación en oncología, apoptosis y desarrollo terapéutico.
Se han encontrado 14 productos de "Survivin"
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MNK8
CAS:MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.Fórmula:C15H12N2O2Pureza:99.74%Forma y color:SolidPeso molecular:252.27ZLDI-8
CAS:<p>ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein.</p>Fórmula:C24H23N3O3SPureza:98.09%Forma y color:SolidPeso molecular:433.52MX106-4C
<p>MX106-4C is a survivin inhibitor that selectively targets ABCB1-positive colorectal cancer cells. It can work synergistically with Doxorubicin for enhanced anticancer effects or restore Doxorubicin sensitivity in drug-resistant ABCB1 cells.</p>Fórmula:C23H25BrN2O2Peso molecular:440.10994HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Forma y color:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.NSC 80467
CAS:NSC 80467 inhibits survivin, targets DNA synthesis, induces γH2AX, and pKAP1 markers of DNA damage.Fórmula:C24H22BrN3O5Pureza:99.25%Forma y color:SolidPeso molecular:512.35HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Forma y color:Lyophilized PowderPeso molecular:The protein has a predicted MW of 50.5 kDa. Due to glycosylation, the protein migrates to 55-63 kDa based on Tris-Bis PAGE result.HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Tetramer Protein, Human, MHC (His & Avi)
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death.Forma y color:Lyophilized PowderPeso molecular:The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.LQZ-7I
CAS:LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFórmula:C20H14F2N4Pureza:99.81% - 99.87%Forma y color:SolidPeso molecular:348.35Cucurbitacin IIA
CAS:1.Fórmula:C32H50O8Pureza:98.62% - 99.87%Forma y color:SolidPeso molecular:562.73Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Forma y color:SolidPeso molecular:244.291-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
CAS:<p>SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib.</p>Fórmula:C21H13ClF3N3O2Pureza:99.41%Forma y color:SolidPeso molecular:431.8Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Forma y color:SolidPeso molecular:443.26GDP366
CAS:<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Fórmula:C20H17N5OSPureza:98.78% - 99.84%Forma y color:SolidPeso molecular:375.45AQIM-I
CAS:<p>AQIM-I is a survivin inhibitor that reduces survivin expression and colony formation. It promotes reactive oxygen species (ROS) production, apoptosis, cell cycle arrest, DNA damage, and autophagy. Moreover, AQIM-I effectively inhibits nonsmall cell lung cancer cells A549, with an IC 50 value of 9 nM [1].</p>Fórmula:C17H13IN2O2Forma y color:SolidPeso molecular:404.20
