Kinesina

NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).

Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a …

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).

Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).

GW108X is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW837331X …

Betamethasone 17-benzoate is a representative steroid. It also can be used in the treatment of …

BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase …

Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used …

Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

SB-743921 is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).

Ispinesib, a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from …

GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).

Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.

ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.

Empesertib is an orally bioavailable and selective inhibitor Mps1(IC50 < 1 nM), with potential antineoplastic activity.

AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.

Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.

MPI-0479605 is an ATP competitive and selective inhibitor.

BRD9876 is a selective inhibitor of MM1S growth.

S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5

CW069( IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity …

Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in …

K858 is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.

GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 …

PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor. PF-2771 inhibits CENP-E motor …

CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).

TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .

EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).

CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = …

Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.