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Kinesina

Kinesina

Los inhibidores de cinesina se dirigen a las proteínas motoras cinesinas, responsables del transporte de carga celular a lo largo de los microtúbulos y que desempeñan un papel clave en la división celular, especialmente durante la mitosis. Las cinesinas están involucradas en el movimiento de cromosomas y otros orgánulos durante la división celular. Inhibir las cinesinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y a la posible muerte celular, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer. En CymitQuimica, ofrecemos una gama diversa de inhibidores de cinesina de alta calidad para apoyar su investigación en biología celular, mitosis y terapia contra el cáncer.

Se han encontrado 66 productos de "Kinesina"

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  • EMD534085

    CAS:
    <p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>
    Fórmula:C25H31F3N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:476.53
  • HR22C16

    CAS:
    <p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>
    Fórmula:C23H23N3O3
    Forma y color:Solid
    Peso molecular:389.45
  • Mps1-IN-4

    CAS:
    <p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>
    Fórmula:C26H31F3N6O2
    Forma y color:Solid
    Peso molecular:516.56
  • KIF18A-IN-3

    CAS:
    <p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>
    Fórmula:C28H38N4O5S2
    Pureza:98.45%
    Forma y color:Solid
    Peso molecular:574.76
  • (R)-Filanesib

    CAS:
    <p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>
    Fórmula:C20H22F2N4O2S
    Forma y color:Solid
    Peso molecular:420.48
  • TC-Mps1-12

    CAS:
    <p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>
    Fórmula:C17H20N6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:324.38
  • Kif15-IN-1

    CAS:
    <p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>
    Fórmula:C20H22N4O5S
    Pureza:99.39% - 99.39%
    Forma y color:Solid
    Peso molecular:430.48
  • Mps-BAY2b

    CAS:
    <p>Mps-BAY2b is a novel MPS1 inhibitor.</p>
    Fórmula:C20H23N5O
    Forma y color:Solid
    Peso molecular:349.43
  • PF-2771

    CAS:
    <p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>
    Fórmula:C29H36ClN5O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:554.08
  • UMK57

    CAS:
    <p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>
    Fórmula:C17H17N3S
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:295.4
  • KSP-IA

    CAS:
    <p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>
    Fórmula:C21H22F2N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:356.41
  • Luvixasertib hydrochloride

    CAS:
    <p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>
    Fórmula:C28H31ClN6O3
    Forma y color:Solid
    Peso molecular:535.04
  • MC-Val-Cit-PAB-Ispinesib

    CAS:
    <p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>
    Fórmula:C59H71ClN10O10
    Forma y color:Solid
    Peso molecular:1115.71
  • CCT251455

    CAS:
    <p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>
    Fórmula:C26H26ClN7O2
    Pureza:99.1% - 99.1%
    Forma y color:Solid
    Peso molecular:503.98
  • Kif15-IN-2

    CAS:
    <p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>
    Fórmula:C20H20N6O4S
    Pureza:98.17%
    Forma y color:Solid
    Peso molecular:440.48
  • NTRC 0066-0

    CAS:
    <p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>
    Fórmula:C33H39N7O2
    Pureza:98.30%
    Forma y color:Solid
    Peso molecular:565.71
  • Litronesib

    CAS:
    <p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>
    Fórmula:C23H37N5O4S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:511.7
  • PVZB1194

    CAS:
    <p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>
    Fórmula:C13H9F4NO2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.28
  • SB-743921 free base

    CAS:
    <p>SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).</p>
    Fórmula:C31H33ClN2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:517.06
  • CCT-271850

    CAS:
    <p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>
    Fórmula:C24H29N7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:431.53