Kinesina
Los inhibidores de cinesina se dirigen a las proteínas motoras cinesinas, responsables del transporte de carga celular a lo largo de los microtúbulos y que desempeñan un papel clave en la división celular, especialmente durante la mitosis. Las cinesinas están involucradas en el movimiento de cromosomas y otros orgánulos durante la división celular. Inhibir las cinesinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y a la posible muerte celular, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer. En CymitQuimica, ofrecemos una gama diversa de inhibidores de cinesina de alta calidad para apoyar su investigación en biología celular, mitosis y terapia contra el cáncer.
Se han encontrado 89 productos para "Kinesina".
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Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Forma y color:SolidPeso molecular:292.35Ref: TM-T4048
1mg46,00€5mg73,00€1mL*10mM (DMSO)81,00€10mg92,00€25mg178,00€50mg295,00€100mg477,00€500mg1.018,00€Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Fórmula:C16H18N2O2SPureza:97.81%Forma y color:SolidPeso molecular:302.39Ref: TM-T3118
1mg34,00€2mg46,00€5mg58,00€1mL*10mM (DMSO)64,00€10mg93,00€25mg147,00€50mg222,00€100mg334,00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Fórmula:C28H24Cl2FN5O2Pureza:97.93% - 98.38%Forma y color:Yellow SolidPeso molecular:552.43Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:Yellow SolidPeso molecular:480.6Mps1-IN-1
CAS:Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )Fórmula:C28H33N5O4SPureza:99.55%Forma y color:Yellow SolidPeso molecular:535.66BAY1217389
CAS:BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Forma y color:White SolidPeso molecular:561.5EMD534085
CAS:EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).Fórmula:C25H31F3N4O2Pureza:98%Forma y color:SolidPeso molecular:476.53CK0106023
CAS:CK0106023, a KSP inhibitor, shows strong antitumor effects in mice, outperforming paclitaxel, and induces monopolar spindles.Fórmula:C30H32BrClN4O2Forma y color:SolidPeso molecular:595.96PF-2771
CAS:PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.Fórmula:C29H36ClN5O4Pureza:98%Forma y color:SolidPeso molecular:554.08TC-Mps1-12
CAS:TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .Fórmula:C17H20N6OPureza:98%Forma y color:SolidPeso molecular:324.38KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Fórmula:C28H38N4O5S2Pureza:98.45%Forma y color:Yellow SolidPeso molecular:574.76Kif15-IN-1
CAS:Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Forma y color:SolidPeso molecular:430.48Litronesib Racemate
CAS:Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.Fórmula:C23H37N5O4S2Forma y color:SolidPeso molecular:511.7SR31527
CAS:SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.Fórmula:C15H14ClN3OSPureza:98.52%Forma y color:Yellow SolidPeso molecular:319.81Ref: TM-T28848
1mg63,00€5mg137,00€1mL*10mM (DMSO)145,00€10mg215,00€25mg439,00€50mg708,00€100mg1.144,00€Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Fórmula:C26H21N3O3Pureza:99.75%Forma y color:SolidPeso molecular:423.46Ref: TM-T11155
1mg80,00€5mg164,00€1mL*10mM (DMSO)178,00€10mg236,00€25mg388,00€50mg560,00€100mg790,00€AM-5308
CAS:AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.Fórmula:C26H35N5O5SPureza:98.95% - 99.58%Forma y color:SolidPeso molecular:529.65Ref: TM-T63726
1mL*10mM (DMSO)A consultar1mg93,00€5mg200,00€10mg304,00€25mg605,00€50mg954,00€100mg1.549,00€Syntelin
CAS:Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.Fórmula:C21H20N6O2S3Forma y color:SolidPeso molecular:484.62CFI-400936
CAS:CFI-400936: potent TTK inhibitor (IC50=3.6nM), potential anticancer, active in cell assays, selective vs. human kinases.Fórmula:C25H27N5O3SForma y color:SolidPeso molecular:477.58Mps-BAY2b
CAS:Mps-BAY2b is a novel MPS1 inhibitor.Fórmula:C20H23N5OForma y color:SolidPeso molecular:349.43HR22C16
CAS:HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.Fórmula:C23H23N3O3Forma y color:SolidPeso molecular:389.45
