Integrin
Los inhibidores de integrinas se dirigen a las integrinas, una familia de receptores en la superficie celular que desempeñan un papel crucial en la adhesión celular, la migración y la transducción de señales. Las integrinas están involucradas en la regulación del ciclo celular, particularmente en procesos como la división y la diferenciación celular. Inhibir las integrinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y la apoptosis, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer y el estudio de la metástasis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de integrinas de alta calidad para apoyar su investigación en la regulación del ciclo celular, la biología del cáncer y el desarrollo terapéutico.
Se han encontrado 224 productos de "Integrin"
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Natalizumab
CAS:<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Pureza:98.00%Forma y color:LiquidPeso molecular:N/ALifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Fórmula:C29H24Cl2N2O7SPureza:99.39% - 99.66%Forma y color:SolidPeso molecular:615.48Irigenin
CAS:<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Fórmula:C18H16O8Pureza:99.50% - 99.85%Forma y color:SolidPeso molecular:360.31Carotegrast methyl
CAS:<p>Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.</p>Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Forma y color:SolidPeso molecular:569.44Tirofiban hydrochloride monohydrate
CAS:<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Forma y color:White SolidPeso molecular:495.07E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37ILK-IN-3
CAS:<p>ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.</p>Fórmula:C10H12N6OPureza:99.69%Forma y color:SolidPeso molecular:232.24Cyclo(RGDyK) trifluoroacetate
CAS:<p>Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.</p>Fórmula:C31H43F6N9O12Pureza:95.28% - ≥95%Forma y color:SolidPeso molecular:847.72TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Forma y color:SolidPeso molecular:474.33BIO-1211
CAS:<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Fórmula:C36H48N6O9Pureza:99.33%Forma y color:SolidPeso molecular:708.8Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Forma y color:SolidPeso molecular:831.96 (free base)GPRP acetate (67869-62-9 free base)
CAS:<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Fórmula:C20H35N7O7Pureza:>99.99%Forma y color:SolidPeso molecular:485.53Bexotegrast
CAS:<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.61Etaracizumab
CAS:<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Pureza:96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.3 (kDa)Muromonab
CAS:<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Pureza:95% - 97.51% (SEC-HPLC)Forma y color:LiquidRO0270608
CAS:<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Fórmula:C24H19Cl3N2O4Pureza:98.26%Forma y color:SolidPeso molecular:505.78Voxalatamab
CAS:<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Forma y color:LiquidRovelizumab
CAS:<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Forma y color:LiquidVepsitamab
CAS:<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Forma y color:LiquidCevostamab
CAS:<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Forma y color:Liquid
